54 research outputs found

    An articulatory and acoustic study of /u/ in preboundary position in French: The interaction of compensatory articulation, neutralization avoidance and featural enhancement

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    27 pagesInternational audienceThis study presents acoustic and electro-magnetic articulography (EMA) data for the back rounded vowel /u/ in preboundary position in French. Five boundary types are examined: the Utterance, the Intonational phrase, the Accentual phrase, the Word and the Syllable. The three speakers studied produce similar acoustic output, with both F1 and F2 becoming lower before stronger prosodic boundaries. However, the Utterance boundary has a particularly strong effect on F1, which is particularly low before this boundary. To achieve the acoustic output observed, the speakers adopt different articulatory strategies at different prosodic boundaries. The strategies observed before the strongest boundaries are tongue dorsum backing (coupled with either raising or lowering, depending on the speaker); tongue tip retraction; and lip protrusion. Somewhat unexpectedly in light of acoustic considerations, lip constriction is observed to be greater before the weaker prosodic boundaries. This result, considered in conjunction with the tongue data and with the lip protrusion data, leads us to suggest that the French speakers in our study are actively aiming to prevent F2 from becoming too high before the weaker prosodic boundaries. We suggest that a high F2 for /u/ may lead to perceptual confusion with the front rounded vowel /y/, which is also present in the French phoneme inventory. This result echoes our previous results for the front unrounded vowel /i/ (Tabain & Perrier, 2005. Articulation and acoustics of /i/ in preboundary position in French. Journal of Phonetics, 33, 77–100), and suggests that the structure of a language's phoneme inventory has important effects on the articulatory strategies adopted by its speakers

    Fundamental frequency characteristics of infant vocalisations: a study in voice quality

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    No clear picture exists of the f0 developmental pattern of typically developing infants. Methodological differences (e.g. type of vocalisations included for analysis) have been found to contribute to this. This paper approaches the f0 characteristics of infant vocalisations from the perspective of modal and non-modal voice qualities to more fully understand their role in the overall developmental contour. The results presented in this paper support the notion that the f0 of infant vocalisations provides insight into how an infant learns to exercise vocal control and that voice quality is a useful category through which to investigate these developments

    Primarni hiperparatireoidizam i serumski kalcij u bolesnica s rakom dojke tijekom procjene niske koštane mase - iskustvo jednog centra

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    The bone health guidelines for breast cancer (BC) patients recommend bone mineral density (BMD) testing. Patients with low BMD and elevated serum calcium levels (SCLs) are further evaluated for primary hyperparathyroidism (PHPT). We aimed to determine the prevalence of PHPT in treated BC patients with low BMD and analyze the association of SCLs with histopathologic tumor features and cancer treatment. This retrospective study included postmenopausal BC patients examined at Osteoporosis Clinic between 2013 and 2020. Clinical and BMD data were collected from patient medical records. Patients with biochemical suspicion of PHPT underwent standard parathyroid imaging procedures. Nine out of 137 (6.6%) patients were diagnosed with PHPT; 8/9 patients underwent parathyroidectomy and one patient was advised to follow-up. Among the rest of 128 non-PHPT patients, higher SCLs showed a trend of positive association with higher tumor grade and axillary lymph node involvement, and received immunotherapy, although without statistical significance. We found a higher prevalence of PHPT in treated BC patients compared to the general population. Higher SCLs show a trend of positive correlation with some more aggressive histopathologic tumor features and with immunotherapy. The results of this study suggest that assessment of SCLs should be routinely performed to rule out PHPT in treated BC patients with low BMD.Smjernice o koštanom zdravlju za bolesnice s rakom dojke (RD) preporučuju ispitivanje mineralne gustoće kostiju (bone mineral density, BMD). U bolesnica s niskom vrijednosti BMD-a i povišenom razinom kalcija u serumu (RKS) dodatno se procjenjuje primarni hiperparatireoidizam (PHPT). Cilj je bio utvrditi učestalost PHPT-a u liječenih bolesnica s RD i sniženom vrijednosti BMD-a te analizirati povezanost RKS s histopatološkim značajkama tumora i onkološkim liječenjem. Retrospektivna studija obuhvatila je postmenopauzalne bolesnice s RD koje su pregledane u Ambulanti za osteoporozu između 2013. i 2020. godine. Klinički podaci i podaci o BMD prikupljeni su iz medicinske dokumentacije. Bolesnice s biokemijskom sumnjom na PHPT podvrgnute su standardnim postupcima snimanja paratireoidnih žlijezda. U devet od 137 (6,6%) bolesnica dijagnosticiran je PHPT; 8/9 bolesnica podvrgnuto je paratireoidektomiji, a jednoj je bolesnici savjetovano praćenje. U ostalih 128 bolesnica bez PHPT-a više RKS pokazale su trend pozitivne povezanosti s višim gradusom tumora, zahvaćenošću aksilarnih limfnih čvorova i primljenom imunoterapijom, iako nije postignuta statistička značajnost. Utvrdili smo veću učestalost PHPT-a u liječenih bolesnica s RD u odnosu na opću populaciju. Više RKS pokazuju trend pozitivne korelacije s nekim agresivnijim histopatološkim značajkama tumora i imunoterapijom. Rezultati ove studije upućuju na to da bi se kod liječenih bolesnica s RD i s niskom vrijednosti BMD-a trebala rutinski provoditi procjena RKS kako bi se isključio PHPT

    "One health" – detection and surveillance of emerging and re-emerging arboviruses in Croatia

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    Posljednjih desetljeća jasno je uočljiv globalni trend porasta učestalosti emergentnih i re-emergentnih zaraznih bolesti koje ugrožavaju čovječanstvo. Najzastupljenije među njima su zoonoze i to ponajprije vektorima prenosive zoonoze. Ovi trendovi pojave novih i širenja postojećih emergentnih i re-emergentnih zoonoza zasigurno će se nastaviti pod utjecajem čimbenika emergencije koji su posljedica današnjeg modernog načina života. Složenost procesa emergencije zaraznih bolesti, koja je posljedica promjena u međuodnosu ljudi, životinja i okoliša, naglasila je potrebu za uvođenjem cjelovitog pristupa očuvanju javnog zdravlja pod nazivom "Jedno zdravlje". U posljednjih nekoliko godina dokazane su po prvi put na području Republike Hrvatske infekcije ljudi dengue virusom, virusom Zapadnog Nila i Usutu virusom, što nedvojbeno potvrđuje promjenu epidemiološke situacije u našoj zemlji. Način otkrivanja i uspostave sustava nadzora navedenih bolesti ističe značaj i učinkovitost zajedničkog multidisciplinarnog rada. Nastavak uvođenja pristupa "Jedno zdravlje" u svakodnevni rad, obveza je svih srodnih struka i jedino jamstvo uspješnog osiguravanja javnog zdravlja u današnjem modernom svijetu.Emerging and re-emerging infectious diseases have increased in incidence over the last several decades and represent a significant threat to global health. The vast majority of emerging pathogens are zoonotic, especially arthropod-borne ones. Increase in the number of outbreaks and geographical range of emerging and re-emerging zoonoses will continue because their emergence is driven by factors resulting from changes in modern lifestyle. These complex and rapidly changing interactions of humans, animals and environment highlighted the need for integrated approach to public health protection under the "One Health" initiative. Recently confirmed autochthonous human cases of dengue virus, West Nile virus and Usutu virus infections have drawn attention to change of epidemiological situation in our country. Detection and the introduction of surveillance program for these diseases point out the importance and efficiency of multidisciplinary collaboration. Enforcing the introduction of "One Health" approach in the everyday work is the obligation of all involved professions and the warranty of successful prevention and public health protection in modern world

    "One health" – detection and surveillance of emerging and re-emerging arboviruses in Croatia

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    Posljednjih desetljeća jasno je uočljiv globalni trend porasta učestalosti emergentnih i re-emergentnih zaraznih bolesti koje ugrožavaju čovječanstvo. Najzastupljenije među njima su zoonoze i to ponajprije vektorima prenosive zoonoze. Ovi trendovi pojave novih i širenja postojećih emergentnih i re-emergentnih zoonoza zasigurno će se nastaviti pod utjecajem čimbenika emergencije koji su posljedica današnjeg modernog načina života. Složenost procesa emergencije zaraznih bolesti, koja je posljedica promjena u međuodnosu ljudi, životinja i okoliša, naglasila je potrebu za uvođenjem cjelovitog pristupa očuvanju javnog zdravlja pod nazivom "Jedno zdravlje". U posljednjih nekoliko godina dokazane su po prvi put na području Republike Hrvatske infekcije ljudi dengue virusom, virusom Zapadnog Nila i Usutu virusom, što nedvojbeno potvrđuje promjenu epidemiološke situacije u našoj zemlji. Način otkrivanja i uspostave sustava nadzora navedenih bolesti ističe značaj i učinkovitost zajedničkog multidisciplinarnog rada. Nastavak uvođenja pristupa "Jedno zdravlje" u svakodnevni rad, obveza je svih srodnih struka i jedino jamstvo uspješnog osiguravanja javnog zdravlja u današnjem modernom svijetu.Emerging and re-emerging infectious diseases have increased in incidence over the last several decades and represent a significant threat to global health. The vast majority of emerging pathogens are zoonotic, especially arthropod-borne ones. Increase in the number of outbreaks and geographical range of emerging and re-emerging zoonoses will continue because their emergence is driven by factors resulting from changes in modern lifestyle. These complex and rapidly changing interactions of humans, animals and environment highlighted the need for integrated approach to public health protection under the "One Health" initiative. Recently confirmed autochthonous human cases of dengue virus, West Nile virus and Usutu virus infections have drawn attention to change of epidemiological situation in our country. Detection and the introduction of surveillance program for these diseases point out the importance and efficiency of multidisciplinary collaboration. Enforcing the introduction of "One Health" approach in the everyday work is the obligation of all involved professions and the warranty of successful prevention and public health protection in modern world

    "One health" – detection and surveillance of emerging and re-emerging arboviruses in Croatia

    Get PDF
    Posljednjih desetljeća jasno je uočljiv globalni trend porasta učestalosti emergentnih i re-emergentnih zaraznih bolesti koje ugrožavaju čovječanstvo. Najzastupljenije među njima su zoonoze i to ponajprije vektorima prenosive zoonoze. Ovi trendovi pojave novih i širenja postojećih emergentnih i re-emergentnih zoonoza zasigurno će se nastaviti pod utjecajem čimbenika emergencije koji su posljedica današnjeg modernog načina života. Složenost procesa emergencije zaraznih bolesti, koja je posljedica promjena u međuodnosu ljudi, životinja i okoliša, naglasila je potrebu za uvođenjem cjelovitog pristupa očuvanju javnog zdravlja pod nazivom "Jedno zdravlje". U posljednjih nekoliko godina dokazane su po prvi put na području Republike Hrvatske infekcije ljudi dengue virusom, virusom Zapadnog Nila i Usutu virusom, što nedvojbeno potvrđuje promjenu epidemiološke situacije u našoj zemlji. Način otkrivanja i uspostave sustava nadzora navedenih bolesti ističe značaj i učinkovitost zajedničkog multidisciplinarnog rada. Nastavak uvođenja pristupa "Jedno zdravlje" u svakodnevni rad, obveza je svih srodnih struka i jedino jamstvo uspješnog osiguravanja javnog zdravlja u današnjem modernom svijetu.Emerging and re-emerging infectious diseases have increased in incidence over the last several decades and represent a significant threat to global health. The vast majority of emerging pathogens are zoonotic, especially arthropod-borne ones. Increase in the number of outbreaks and geographical range of emerging and re-emerging zoonoses will continue because their emergence is driven by factors resulting from changes in modern lifestyle. These complex and rapidly changing interactions of humans, animals and environment highlighted the need for integrated approach to public health protection under the "One Health" initiative. Recently confirmed autochthonous human cases of dengue virus, West Nile virus and Usutu virus infections have drawn attention to change of epidemiological situation in our country. Detection and the introduction of surveillance program for these diseases point out the importance and efficiency of multidisciplinary collaboration. Enforcing the introduction of "One Health" approach in the everyday work is the obligation of all involved professions and the warranty of successful prevention and public health protection in modern world
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