Enantioselective Narasaka-Heck Cyclizations:Synthesis of Tetrasubstituted Nitrogen-Bearing Stereocenters

A SPINOL-derived P,N-ligand system enables Pd-catalyzed 5-exo cyclization of oxime esters with trisubstituted alkenes to generate dihydropyrroles in up to 86% yield and 95 : 5 e.r.</p