HOME-BASED VS IN CENTER AEROBIC EXERCISE: IMPACT ON CARDIORESPIRATORY (CR) AND FUNCTIONAL CAPACITIES (FC) OF NONDIALYSIS DEPENDENT OVERWEIGHT CKD PATIENTS

We tested the hypothesis that home-based exercise (HE) was similarly effective to the in center exercise (CE) on CR and FC. This is a randomized controlled study that included 35 sedentary patients (23 men; 53±8.1 years, BMI 30.7±4.2 kg/m2, creatinine clearance 30.9±4.2 mL/min; DM 23%). Patients were randomly assigned to HE (n=11), CE (n=12) or control (CO, n=12) groups. CE and HE underwent to an identical exercise program, three times per week during 12 weeks. The CO group remained without practicing exercise during follow up. The CE patients trained on a treadmill while the HE patients were instructed how to perform the training at home and were monitored by phone once a week. The training resulted in increase 20% and 19% in maximal ventilation (p<0.05), 14.5% and 11% in speed of VO2peak (p<0.01), 25.7% and 17.5% in speed of ventilatory threshold (p<0.01) and 20% and 17.2% in speed of respiratory compensation point (p<0.001) only in CE and HE groups respectively. In the exercise groups, improvement in functional capacity tests such as 2-min step (p<0.01), sit-stand (p<0.001) and arm curl (p<0.001) was observed. Blood pressure decreassed only in the exercise groups (p<0.01), in conclusion HE promoted similarly effective that CE and can be effectively applied for this particular group of patients