Symptoms in unilateral vestibular hypofunction are associated with number of catch-up saccades and retinal error: results from the population-based KORA FF4 study

ObjectiveThe presence and intensity of symptoms vary in patients with unilateral vestibular hypofunction. We aimed to determine which saccadic and vestibulo-ocular reflex parameters best predict the presence of symptoms in unilateral vestibular hypofunction in order to better understand vestibular compensation and its implications for rehabilitation therapy.MethodsVideo head impulse test data were analyzed from a subpopulation of 23 symptomatic and 10 currently symptom-free participants with unilateral vestibular hypofunction, embedded in the KORA (Cooperative Health Research in the Region of Augsburg) FF4 study, the second follow-up of the KORA S4 population-based health survey (2,279 participants).ResultsA higher number of catch-up saccades, a higher percentage of covert saccades, and a larger retinal error at 200 ms after the onset of the head impulse were associated with relevant symptoms in participants with unilateral vestibular hypofunction (p = 0.028, p = 0.046, and p = 0.038, respectively). After stepwise selection, the number of catch-up saccades and retinal error at 200 ms remained in the final logistic regression model, which was significantly better than a null model (p = 0.014). Age, gender, saccade amplitude, saccade latency, and VOR gain were not predictive of the presence of symptoms.ConclusionThe accuracy of saccadic compensation seems to be crucial for the presence of symptoms in unilateral vestibular hypofunction, highlighting the role of specific gaze stabilization exercises in rehabilitation. Early saccades, mainly triggered by the vestibular system, do not seem to compensate accurately enough, resulting in a relevant retinal error and the need for more as well as more accurate catch-up saccades, probably triggered by the visual system

El dano moral en la Jurisprudencia de la Excelentísima Corte Suprema de Chile. Su criterio frente a este tema, y el alcance de sus fallos al respecto.

69 p.El derecho de daños, ha experimentado en el ultimo tiempo un crecimiento notable, especialmente en derecho comparado. En nuestro país no esta ausente esta tendencia. Todo aquel que provoca un daño debe indemnizarlo. No tiene mayor dificultad cuando son daños patrimoniales, puesto que acreditados los presupuestos que hacen procedente la indemnización del daño, la prueba del daño patrimonial es acorde a los medios y formas que la ley ha entregado desde la vigencia del Código Civil. Distinta es la situación de distintas clases de daños, que acarrean una serie de perjuicios que no son avaluables en dinero. La determinación de lo que se ha entendido como daño moral, los parámetros que se consideran para su determinación , exigencias de prueba o falta de ella, requisitos exigidos para declararlos, es parte de lo que modestamente ha pretendido este trabajo de memoria para optar al grado de licenciada en Ciencias Jurídicas y Sociales