German S3 guideline "actinic keratosis and cutaneous squamous cell carcinoma" – long version of the update 2023

Actinic keratosis (AK) are common lesions in light-skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major disease burden, especially among the elderly. To establish an evidence-based framework for clinical decision making, the guideline “actinic keratosis and cutaneous squamous cell carcinoma” was updated and expanded by the topics cutanepus squamous cell carcinoma in situ (Bowen’s disease) and actinic cheilitis. This guideline was developed at the highest evidence level (S3) and is aimed at dermatologists, general practitioners, ear nose and throat specialists, surgeons, oncologists, radiologists and radiation oncologists in hospitals and office-based settings, as well as other medical specialties, policy makers and insurance funds involved in the diagnosis and treatment of patients with AK and cSCC

NEETs als neue Zielgruppe der Sozialforschung und der Arbeitsmarktpolitik. Eine qualitative Studie im Raum Dresden.

Das Dresdner Institut für regionale Innovation und Sozialforschung e.V. (IRIS) mit Dr. Enrico Nerli Ballati, Mareike Fritz und Jan Köhler forscht derzeit zu jungen Erwachsenen im NEET-Status ("Not in Education, Employment or Training"). Dabei handelt es sich um einen neuen Indikator, der – in Ergänzung zum Indikator Jugendarbeitslosigkeit – differenziert und tiefgehend erfassen kann, welchen Problematiken sich Jugendliche und junge Erwachsene bei dem Übergang in Arbeit stellen müssen. NEET ist schon jetzt ein wichtiger Begriff in der europäischen Arbeitsmarktpolitik und wird in Zukunft beim Thema Jugendarbeitslosigkeit eine immer größere Rolle spielen. Die Frage ist für welche Personengruppe dieser Zustand als Ausgrenzungsrisiko oder als überbrückbare Wartephase konzeptualisiert werden kann

NEET-Indikator als Maß für soziale Exklusion? Potenziale und Grenzen des Konzeptes NEET in seiner arbeitsmarktpolitischen Anwendung.

Jugendliche und junge Erwachsene NEETs (Not in Education, Employment or Training) stellen die Zielgruppe des EU-Programms Jugendgarantie dar. Bisherige Untersuchungen legen nahe, dass dieser Indikator verschiedene kumulative Problemlagen und Akteure mit erhöhtem Ausgrenzungsrisiko erfassen kann. Mittels einer qualitativen Studie zu NEETs im Raum Dresden wird das Ausgrenzungsrisiko der Betroffenen durch vergleichende Fallanalysen betrachtet. Auf der Basis der Ergebnisse werden die Potentiale und Grenzen des Konzeptes NEET in seiner arbeitsmarktpolitischen Anwendung kritisch diskutiert

Small aliquot and single grain IRSL and post-IR IRSL dating of fluvial and alluvial sediments from the Pativilca valley, Peru

Infrared stimulated luminescence (IRSL) and post-IR IRSL are applied to small aliquots and single grains to determine the equivalent dose (De) of eleven alluvial and fluvial sediment samples collected in the Pativilca valley, Central Peru at ca. 10°S latitude. Small aliquot De distributions are rather symmetric and display over-dispersion values between 15 and 46%. Small aliquot g-values range between 4 and 8% per decade for the IRSL and 1 and 2% per decade for the post-IR IRSL signal. The single grain De distributions are highly over-dispersed with some of them skewed to higher doses, implying partial bleaching; this is especially true for the post-IR IRSL. Measurements of a modern analog reveal that residuals due to partial bleaching are present in both the IRSL as well as the post-IR IRSL signal. The g-values of individual grains exhibit a wide range with high individual uncertainties and might contribute significantly to the spread of the single grain De values, at least for the IRSL data. Electron Microprobe Analysis performed on single grains reveal that a varying K-content can be excluded as the origin of over-dispersion. Final ages for the different approaches are calculated using the Central Age Model and the Minimum Age Model (MAM). The samples are grouped into well-beached, potentially well-bleached and partially bleached according to the evaluation of the single grain distributions and the agreement of age estimates between methods. The application of the MAM to the single grain data resulted in consistent age estimates for both the fading corrected IRSL and the post-IR IRSL ages, and suggests that both approaches are suitable for dating these samples. Keyword