Flow curvature effects on dynamic behaviour of a novel vertical axis tidal current turbine: numerical and experimental analysis

The paper deals with performances analysis of vertical axis turbine to exploit tidal marine currents. Flow curvature effects on performences of a novel vertical axis turbine have been investuigated. It has been shown that the flow curvature effect allows to design properly an accurate airfoil shape to increase turbine performances

Search for single production of a Vector-Like partner of the bottom quark in the bH(bb) final state in pp collisions at √s = 13 TeV with the ATLAS detector

A search is presented for single-produced vector-like B quark decaying to a Standard Model b-quark and a Higgs boson, itself decaying into a b-quark pair. The B decay system is reconstructed as an association of a large-radius jet and a small-radius jet, respectively taken to reflect the secondary Higgs decay system and the $b$ quark produced in the immediate resonance decay. The search is the first at ATLAS to probe the Higgs to b-quark pair final state in Run-2, and aims at extending the region of the M(B) phase space the current exclusion limits, set by the pair production combination search at 1220 GeV for a Vector-Like B quark occurring as an isospin singlet. For this purpose, a newly designed and optimised event selection was implemented for maximal sensitivity in the 1000-2000 GeV invariant mass region, and a particular effort was dedicated in researching and implementing data-driven modelling techniques to provide a reliable estimation of the main, QCD-Driven, background source to the search. A binned likelihood fit is set up for the statistical interpretation of the results, which are presented in the form of mass- and coupling-dependent 95% CLs exclusion limits on the production cross section of a VLQ-like signal

Hypovitaminosis D: a novel finding in primary ciliary dyskinesia

BACKGROUND: A relationship between low levels of serum vitamin D and respiratory infections has been established. No study has examined the frequency and clinical relevance of vitamin D deficiency in patients with primary ciliary dyskinesia (PCD). METHODS: Vitamin D levels were measured in 22 PCD patients (7 females, 10.5 years, range, 2-34 years). In PCD, pulmonary function tests (PFTs), sputum microbiology, self-reported physical activity (PA) level, and quality of life (QoL) by means of the Saint George's Respiratory Questionnaire (SGRQ), were also assessed. RESULTS: Seventy-two percent of PCD patients were vitamin-D deficient-to-insufficient and 28% were sufficient. No differences in PFTs parameters were found between vitamin D deficiency-to-insufficiency and sufficiency groups. Patients with vitamin D deficiency-to-insufficiency had significantly higher SGRQ total scores, and thus poorer QoL (p = 0.03). Seventy-nine percent of PCD subjects had limitations in performing vigorous activities, and 53% performed less than 3 hours of PA per week. Vitamin D deficiency-to-insufficiency and sufficiency groups did not show any differences in age at PCD diagnosis or at onset of respiratory symptoms, BMI, atopy, current asthma or bronchiectasis. However, 79% of patients with bronchiectasis had vitamin D deficiency-to-insufficiency. No differences were found in the rate of positive sputum cultures and in the number of antibiotic courses between the two groups. CONCLUSIONS: Hypovitaminosis D is common in PCD patients, and is associated with poorer QoL. We recommend the assessment and treatment of hypovitaminosis D to be included in the routine management of PCD

On the Virtualization of CUDA Based GPU Remoting on ARM and X86 Machines in the GVirtuS Framework

The astonishing development of diverse and different hardware platforms is twofold: on one side, the challenge for the exascale performance for big data processing and management; on the other side, the mobile and embedded devices for data collection and human machine interaction. This drove to a highly hierarchical evolution of programming models. GVirtuS is the general virtualization system developed in 2009 and firstly introduced in 2010 enabling a completely transparent layer among GPUs and VMs. This paper shows the latest achievements and developments of GVirtuS, now supporting CUDA 6.5, memory management and scheduling. Thanks to the new and improved remoting capabilities, GVirtus now enables GPU sharing among physical and virtual machines based on x86 and ARM CPUs on local workstations, computing clusters and distributed cloud appliances

Lung structure and function similarities between primary ciliary dyskinesia and mild cystic fibrosis: a pilot study

BACKGROUND: Primary ciliary dyskinesia (PCD) and cystic fibrosis (CF) are increasingly compared. There are no chest magnetic resonance imaging (MRI) comparative studies of PCD and CF. We assessed clinical, functional, microbiological and MRI findings in PCD and mild CF patients in order to evaluate different expression of lung disease. METHODS: Twenty PCD (15.1 years) and 20 CF subjects with mild respiratory impairment (16 years, 70% with pancreatic insufficiency) underwent MRI, spirometry, and sputum cultures when clinically stable. MRI was scored using the modified Helbich system. RESULTS: PCD was diagnosed later than CF (9.9 versus 0.6 years, p = 0.03), despite earlier symptoms (0.1 versus 0.6 years, p = 0.02). In the year preceding the study, patients from both groups underwent two systemic antibiotic courses (p = 0.48). MRI total scores were 11.6 ± 0.7 and 9.1 ± 1 in PCD and CF, respectively. FEV1 and FVC Z-scores were -1.75 (range, -4.6-0.7) and -0.6 (-3.9-1.8) in PCD, and -0.9 (range, -5.4-2.3) and -0.3 (-3.4-2.5) in CF, respectively. No difference was found between lung function or structure, despite a higher MRI subscore of collapse/consolidation in PCD versus CF (1.6 ± 0.1 and 0.6 ± 0.2, p < 0.001). These findings were confirmed after data-control for diagnostic delay. Pseudomonas aeruginosa and Staphylococcus aureus were more frequent in CF than in PCD (p = 0.05 and p = 0.003, respectively). CONCLUSIONS: MRI is a valuable radiation-free tool for comparative PCD and CF lung disease assessment. Patients with PCD may exhibit similar MRI and lung function changes as CF subjects with mild pulmonary disease. Delay in PCD diagnosis is unlikely the only determinant of similarities

Dynamic behavior of novel vertical axis tidal current turbine: numerical and experimental investigations

This paper presents a summary of the recent work done by the authors regarding the design, construction and test of a novel patented vertical axis and variable pitching blade hydro turbine, named KOBOLD, capable of harnessing clean and renewable energy from marine tidal currents. The KOBOLDturbine, currently moored in Messina Strait, between mainland Italy and Sicily island, is the only existing turbine of this type devoted to exploit tidal currents, and has a 25% global system efficiency. Theoretical analysis and numerical prediction performanceshave been compared and validated with experimental test results on both model and real scale turbines. Moreover, the recent activities in terms of numerical and experimental investigations on vertical axis hydro turbines are presente

Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings

Abstract Background Primary ciliary dyskinesia (PCD) is associated with pulmonary involvement that requires periodical assessment. Chest high-resolution computed tomography (HRCT) has become the method of choice to evaluate chronic lung disease, but entails exposure to ionizing radiation. Magnetic resonance imaging (MRI) has been proposed as a potential radiation-free technique in several chest disorders. Aim of our study is to evaluate whether high-field MRI is as effective as HRCT in identifying PCD pulmonary abnormalities. We also analyzed the relationships between the severity and extension of lung disease, and functional data. Methods Thirteen PCD patients (8 children/5 adults; median age, 15.2 yrs) underwent chest HRCT and high-field 3T MRI, spirometry, and deep throat or sputum culture. Images were scored using a modified version of the Helbich system. Results HRCT and MRI total scores were 12 (range, 6–20) and 12 (range, 5–17), respectively. Agreement between HRCT and MRI scores was good or excellent (r > 0.8). HRCT and MRI total scores were significantly related to forced vital capacity (r = -0.5, p = 0.05; and r = -0.7, p = 0.009, respectively) and forced expiratory volume at 1 second (r = -0.6, p = 0.03; and r = -0.7, p = 0.009, respectively). Conclusion Chest high-field 3T MRI appears to be as effective as HRCT in assessing the extent and severity of lung abnormalities in PCD. MRI scores might be used for longitudinal assessment and be an outcome surrogate in future studies.</p

Dynamic Behaviour of the Patented Kobold Tidal Current Turbine: Numerical and Experimental Aspects

This paper provides a summary of the work done at DPA on numerical and experimental investigations of a novel patented vertical axis and variable pitching blades hydro turbine designed to harness energy from marine tidal currents. Ponte di Archimede S.p.A. Company, located in Messina, Italy, owns the patented KOBOLD turbine that is moored in the Messina Strait, between the mainland and Sicily. The turbine has a rotor with a diameter of 6 meters, three vertical blades of 5 meters span with a 0.4 m chord ad hoc designed curved airfoil, producing high lift with no cavitation. The rated power is 160 kW with 3.5 m/s current speed, which means 25% global system efficiency. The VAWT and VAWT_DYN computer codes, based on Double Multiple Steamtube, have been developed to predict the steady and dynamic performances of a cycloturbine with fixed or self-acting variable pitch straight-blades. A theoretical analysis and a numerical prediction of the turbine performances as well as experimental test results on both a model and the real scale turbine will be presented and discussed.