Threading Through Macrocycles Enhances the Performance of Carbon Nanotubes as Polymer Fillers

In this work we study the reinforcement of polymers by mechanically interlocked derivatives of single-walled carbon nanotubes (SWNTs). We compare the mechanical properties of fibers made of polymers and of composites with pristine single-walled carbon nanotubes (SWNTs), mechanically interlocked derivatives of SWNTs (MINTs) and the corresponding supramolecular models. Improvements of both Young's modulus and tensile strength of up to 200 % were observed for the polystyrene-MINTs samples with an optimized loading of just 0.01 wt.%, while the supramolecular models with identical chemical composition and loading showed negligible or even detrimental influence. This behavior is found for three different types of SWNTs and two types of macrocycles. Molecular dynamics simulations show that the polymer adopts an elongated conformation parallel to the SWNT when interacting with MINT fillers, irrespective of the macrocycle chemical nature, whereas a more globular structure is taken upon facing with either pristine SWNTs or supramolecular models. The MINT composite architecture thus leads to a more efficient exploitation of the axial properties of the SWNTs and of the polymer chain at the interface, in agreement with experimental results. Our findings demonstrate that the mechanical bond imparts distinctive advantageous properties to SWNT derivatives as polymer fillers.Comment: 39 pages, 19 figure

On the Gas Surrounding High Redshift Galaxy Clusters

Francis & Hewett (1993) identified two 10-Mpc scale regions of the high redshift universe that were seemingly very overdense in neutral hydrogen. Subsequent observations showed that at least one of these gas-rich regions enveloped a cluster of galaxies at redshift 2.38. We present improved observations of the three background QSOs with sightlines passing within a few Mpc of this cluster of galaxies. All three QSOs show strong neutral hydrogen absorption at the cluster redshift, suggesting that this cluster (and perhaps all high redshift clusters) may be surrounded by a ~5 Mpc scale region containing ~ 10^12 solar masses of neutral gas. If most high redshift clusters are surrounded by such regions, we show that the gas must be in the form of many small ( 0.03 cm^-3) clouds, each of mass < 10^6 solar masses. These clouds are themselves probably gathered into > 20 kpc sized clumps, which may be galaxy halos or protogalaxies. If this gas exists, it will be partially photoionised by the UV background. We predict the diffuse Ly-alpha flux from this photoionisation, and place observational limits on its intensity.Comment: 19 pages, 5 figures. Accepted for publication in PAS

Bacterial activity and community composition response to the size-reactivity of dissolved organic matter

Heterotrophic bacteria respond dynamically to variations in organic matter availability in the dark ocean. However, our knowledge on how the differences in sized and/or reactivity of dissolved organic matter (DOM) affect the bacterial community dynamics is still scarce. Our study aims to investigate the response of bacterial activity and community composition to the degradability of filtered and of size-fractionated DOM. A natural bacterial community isolated from Mediterrean Water (MW; at 1000 m depth) was inoculated in seawater from the same location subjected to three different treatments: 0.2µm-filtered seawater (control), low molecular weight fraction (LMW) obtained by ultrafiltration, and the combination of low and high molecular weight fractions at the original ratio (H+L). Bacterial abundance and activity was monitored every 24h over 6 days, while bacterial community composition and DOM characterization were assessed at the beginning (day 0), middle (day 4) and at the end of the experiment (day 6). Low (LNA) and high nucleic acid content (HNA) bacterial abundance, as well as leucine incorporation rates, were consistently higher in the H+L incubations than in the LMW treatments, indicating different reactivity of the two organic matter size fractions. Moreover, actively respiring cells, estimated as CTC-positive cells, highly correlated to humic-like substances (FDOM-M; R=0.7, P<0.05, n=9, Spearman Rank Order), particularly in the H+L incubations. Interestingly, LNA cell abundance was highly correlated with the slope ratio (SR) values (R=-0.8, P<0.05, n=9, Spearman Rank Order), indicating that bacteria belonging to the LNA population are tightly linked to the molecular weight or aromaticity of the DOM. Taken together, our results indicate differences in the bio-reactivity of the low and high molecular weight size classes of DOM associated to the phylogenetic composition of the bacterial communities

Plasma and surface diagnostics of silicon nitride thin film coatings generated by SiH4+NH3 RF discharges.

Although plasma processing in low pressure electric discharge reactors has become an extensive and critical step in the fabrication of microelectronic devices, its development has been carried out mostly empirically so far, by changing external reactor parameters in order to develop the best achievable film properties, whereas the intrinsic state of the plasma has been largely unknown [1, 2]. In this work, silicon nitride (SiN) thin films have been grown on silicon samples and on AlGaN/GaN High Electron Mobility Transistors (HEMT) by Plasma Enhanced Chemical Vapor Deposition (PE-CVD). The SiN coatings have been produced in a RF discharge reactor, employing SiH4 and NH3 as precursors, at different electric powers and gas flow ratios. During depositions, the plasmas have been characterized by mass and time resolved quadrupole mass spectrometry, and the depletion ratios of parent gases have been observed. Afterwards, the refractive indexes and growth rates of the films have been analysed by ellipsometry, and their composition, by Fourier Transform Infrared Spectroscopy. The electrical characteristics and frequency responses of these films when deposited on HEMT (where they are just usually employed to passivate these devices against current collapses) have been studied too by means of DC, pulsed currents, and small signal RF measurements. The plasma characteristics for the different deposition conditions have been correlated with the subsequent changes in the properties of the films. A comparison with the results previously reported in the literature is addressed

New Observations of the Interstellar Medium in the Lyman Break Galaxy MS 1512-cB58

We present the results of a detailed study of the interstellar medium of MS 1512-cB58, an L* Lyman break galaxy at z = 2.7276, based on new spectral observations obtained with the Echelle Spectrograph and Imager on the Keck II telescope at 58 km/s resolution. We focus in particular on the chemical abundances and kinematics of the interstellar gas and our main findings are as follows. Even at this relatively early epoch, the ISM of this galaxy is already highly enriched in elements released by Type II supernovae; the abundances of O, Mg, Si, P, and S are all about 2/5 of their solar values. In contrast, N and the Fe-peak elements Mn, Fe, and Ni are underabundant by a factor of about 3. Based on current ideas of stellar nucleosynthesis, these results can be understood if most of the metal enrichment in cB58 has taken place within the last 300 million years, the timescale for the release of N from intermediate mass stars. cB58 appears to be an example of a galaxy in the process of converting its gas into stars on a few dynamical timescales; quite possibly we are witnessing the formation of a galactic bulge or an elliptical galaxy. The energetic star formation activity has stirred the interstellar medium to high velocities of up to 1000 km/s. The net effect is a bulk outflow of the ISM at a speed of 255 km/s and at a rate which exceeds the star formation rate. It is unclear whether this gas will be lost or retained by the galaxy. We point out that the chemical and kinematic properties of cB58 are markedly different from those of most damped Lyman alpha systems at the same redshift.Comment: 38 pages, LaTeX, 9 Postscript Figures. Accepted for publication in the Astrophysical Journal. Sections 3.3 and 5.3 expanded, and two additional figures included, following referee's repor

Neuronal deletion of GSK3beta increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2

BACKGROUND: In the adult central nervous system, axonal regeneration is abortive. Regulators of microtubule dynamics have emerged as attractive targets to promote axonal growth following injury as microtubule organization is pivotal for growth cone formation. In this study, we used conditioned neurons with high regenerative capacity to further dissect cytoskeletal mechanisms that might be involved in the gain of intrinsic axon growth capacity. RESULTS: Following a phospho-site broad signaling pathway screen, we found that in conditioned neurons with high regenerative capacity, decreased glycogen synthase kinase 3β (GSK3β) activity and increased microtubule growth speed in the growth cone were present. To investigate the importance of GSK3β regulation during axonal regeneration in vivo, we used three genetic mouse models with high, intermediate or no GSK3β activity in neurons. Following spinal cord injury, reduced GSK3β levels or complete neuronal deletion of GSK3β led to increased growth cone microtubule growth speed and promoted axon regeneration. While several microtubule-interacting proteins are GSK3β substrates, phospho-mimetic collapsin response mediator protein 2 (T/D-CRMP-2) was sufficient to decrease microtubule growth speed and neurite outgrowth of conditioned neurons and of GSK3β-depleted neurons, prevailing over the effect of decreased levels of phosphorylated microtubule-associated protein 1B (MAP1B) and through a mechanism unrelated to decreased levels of phosphorylated cytoplasmic linker associated protein 2 (CLASP2). In addition, phospho-resistant T/A-CRMP-2 counteracted the inhibitory myelin effect on neurite growth, further supporting the GSK3β-CRMP-2 relevance during axon regeneration. CONCLUSIONS: Our work shows that increased microtubule growth speed in the growth cone is present in conditions of increased axonal growth, and is achieved following inactivation of the GSK3β-CRMP-2 pathway, enhancing axon regeneration through the glial scar. In this context, our results support that a precise control of microtubule dynamics, specifically in the growth cone, is required to optimize axon regrowth

Measurement of the Resonant dμtd\mu t Molecular Formation Rate in Solid HD

Measurements of muon-catalyzed dt fusion ($d\mu t \to ^4He+n+\mu^-$) in solid HD have been performed. The theory describing the energy dependent resonant molecular formation rate for the reaction $\mu t$ + HD $\to [(d\mu t)pee]^*$ is compared to experimental results in a pure solid HD target. Constraints on the rates are inferred through the use of a Monte Carlo model developed specifically for the experiment. From the time-of- flight analysis of fusion events in 16 and 37 $\mu g\cdot cm^{-2}$ targets, an average formation rate consistent with 0.897$\pm$(0.046)$_{stat}\pm$ (0.166)$_{syst}$ times the theoretical prediction was obtained.Comment: 4 pages, 5 figure

Electronic tuning and uniform superconductivity in CeCoIn5

We report a globally reversible effect of electronic tuning on the magnetic phase diagram in CeCoIn_{5} driven by electron (Pt and Sn) and hole (Cd, Hg) doping. Consequently, we are able to extract the superconducting pair breaking component for hole and electron dopants with pressure and co-doping studies, respectively. We find that these nominally non-magnetic dopants have a remarkably weak pair breaking effect for a d-wave superconductor. The pair breaking is weaker for hole dopants, which induce magnetic moments, than for electron dopants. Furthermore, both Pt and Sn doping have a similar effect on superconductivity despite being on different dopant sites, arguing against the notion that superconductivity lives predominantly in the CeIn_{3} planes of these materials. In addition, we shed qualitative understanding on the doping dependence with density functional theory calculations.Comment: Accepted for publication in Phys. Rev. Lett. (October 1, 2012

Initial Response of Mature, Experienced Runners to Barefoot Running: Transition to Forefoot Strike

Introduction Forefoot strike has been advocated for many runnersbecause of the relatively lower impact and push-off forces comparedto a heel strike. The purpose of this study was to explore the abilityof mature (&gt; 30 years old), experienced runners to transition from aheel foot strike to a forefoot strike when first introduced to barefootrunning on a treadmill. We hypothesized: 1) mature runners who heelstrike while wearing traditional training shoes would persist in heelstriking immediately following a switch to barefoot, 2) mean shoeheel-to-toe drop would be significantly greater in runners who persistin heel striking when running barefoot compared to those who transitionto a forefoot strike pattern, and 3) there would be a significantdecrease in heel striking in the barefoot condition as running speedsincreased. Methods This was a controlled crossover laboratory study. Thirty-three experienced runners (average 23.4 miles per week) withan average age of 45.6 years were recruited for this study. The participantsfirst ran in their standard running shoes and subsequentlybarefoot. A motion capture system was utilized to detect and analyzeany transition from heel strike to forefoot strike made by study participants. Results Of the 26 participants who were classified as heel strikerunners in their running shoes, 50% (13/26, p = 0.001) transitionedto forefoot strike when changing from running in shoes to runningbarefoot. Conclusions The injuries associated with transition from standardrunning shoes to barefoot running or minimalist shoes may be influencedby the persistence of heel striking in mature runners. Olderexperienced runners may have limited ability to transition from heelto forefoot striking when first introduced to barefoot running. Maturerunners should be cautious when beginning a minimalist shoe orbarefoot running regimen