89 research outputs found

    Ingeniería de requerimientos aplicada a sistemas sensibles al contexto : Revisión de la literatura

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    El objetivo de este trabajo de investigación consiste en proponer un modelo para la especificación de requerimientos para un sistema sensible al contexto. Este tipo de sistemas, que adaptan su comportamiento en función de los cambios captados en el entorno, resultan complejos a la hora de entender y definir el dominio de la aplicación. Los métodos tradicionales de ingeniería de requerimientos no contemplan ciertas necesidades, propias de estas aplicaciones, como ser entre otras la definición de servicios sensibles al contexto, tipos de contexto, calidad y estado del contexto. El grupo de investigación se encuentra analizando los métodos y las herramientas propuestas por varios autores, quienes abordan el tema desde distintos enfoques. La investigación se plantea basándola en tres pilares, la especificación de requerimientos, los sistemas sensibles al contexto y un caso práctico de aplicación, cuyo dominio aún no ha sido definido.Eje: Ingeniería de SoftwareRed de Universidades con Carreras en Informática (RedUNCI

    AGAMOS: A graph-based approach to modulo scheduling for clustered microarchitectures

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    This paper presents AGAMOS, a technique to modulo schedule loops on clustered microarchitectures. The proposed scheme uses a multilevel graph partitioning strategy to distribute the workload among clusters and reduces the number of intercluster communications at the same time. Partitioning is guided by approximate schedules (i.e., pseudoschedules), which take into account all of the constraints that influence the final schedule. To further reduce the number of intercluster communications, heuristics for instruction replication are included. The proposed scheme is evaluated using the SPECfp95 programs. The described scheme outperforms a state-of-the-art scheduler for all programs and different cluster configurations. For some configurations, the speedup obtained when using this new scheme is greater than 40 percent, and for selected programs, performance can be more than doubled.Peer ReviewedPostprint (published version

    Bacterial lysis through interference with peptidoglycan synthesis increases biofilm formation by nontypeable haemophilus influenzae

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    Nontypeable Haemophilus influenzae (NTHi) is an opportunistic pathogen that mainly causes otitis media in children and community-acquired pneumonia or exacerbations of chronic obstructive pulmonary disease in adults. A large variety of studies suggest that biofilm formation by NTHi may be an important step in the pathogenesis of this bacterium. However, the underlying mechanisms involved in this process are poorly elucidated. In this study, we used a transposon mutant library to identify bacterial genes involved in biofilm formation. The growth and biofilm formation of 4,172 transposon mutants were determined, and the involvement of the identified genes in biofilm formation was validated in in vitro experiments. Here, we present experimental data showing that increased bacterial lysis, through interference with peptidoglycan synthesis, results in elevated levels of extracellular DNA, which increased biofilm formation. Interestingly, similar results were obtained with subinhibitory concentrations of β-lactam antibiotics, known to interfere with peptidoglycan synthesis, but such an effect does not appear with other classes of antibiotics. These results indicate that treatment with β-lactam antibiotics, especially for β-lactam-resistant NTHi isolates, might increase resistance to antibiotics by increasing biofilm formation

    Optical and visual quality with physical and visually simulated presbyopic multifocal contact lenses

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    16 pags. 6 figs., 1 tab.Purpose: As multifocal contact lenses (MCLs) expand as a solution for presbyopia correction, a better understanding of their optical and visual performance becomes essential. Also, providing subjects with the experience of multifocal vision before contact lens fitting becomes critical, both to systematically test different multifocal designs and to optimize selection in the clinic. In this study, we evaluated the ability of a simultaneous vision visual simulator (SimVis) to represent MCLs. Methods: Through focus (TF) optical and visual quality with a center-near aspheric MCL (low, medium and high near adds) were measured using a multichannel polychromatic Adaptive Optics visual simulator equipped with double-pass, SimVis (temporal multi-plexing), and psychophysical channels to allow measurements on-bench and in vivo. On bench TF optical quality of SimVis-simulated MCLs was obtained from double-pass (DP) images and images of an E-stimulus using artificial eyes. Ten presbyopic subjects were fitted with the MCL. Visual acuity (VA) and DP retinal images were measured TF in a 4.00 D range with the MCL on eye, and through SimVis simulations of the same MCLs on the same subjects. Results: TF optical (on bench and in vivo) and visual (in vivo) quality measurements captured the expected broadening of the curves with increasing add. Root mean square difference between real and SimVis-simulated lens was 0.031/0.025 (low add), 0.025/0.015 (medium add), 0.019/0.011 (high add), for TF DP and TF LogMAR VA, respectively. A shape similarity metric shows high statistical values (lag κ = 0), rho = 0.811/0.895 (low add), 0.792/0.944 (medium add), and 0.861/0.915 (high add) for TF DP/LogMAR VA, respectively. Conclusions: MCLs theoretically and effectively expand the depth of focus. A novel simulator, SimVis, captured the through-focus optical and visual performance of the MCL in most of the subjects. Visual simulators allow subjects to experience vision with multifocal lenses prior to testing them on-eye. Translational Relevance: Simultaneous visual simulators allow subjects to experience multifocal vision non-invasively. We demonstrated equivalency between real multifocal contact lenses and SimVis-simulated lenses. The results suggest that SimVis is a suitable technique to aid selection of presbyopic corrections in the contactology practice.Supported by the European Research Council (ERC-2011-AdC 294099) to SM; Spanish Government (FIS2017-84753R) to SM, and pre-doctoral fellowship (FPU16/01944) to SA; Collaborative agreement with Johnson & Johnson Vision, Inc., Research & Development, Jacksonville, FL, USA

    Informe nº 0

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    Este informe presenta información sobre las concentraciones de hidrocarburos poliaromáticos totales presentes en el sedimento en muestras correspondientes a 23 estaciones localizadas en la plataforma continental gallega, recogidas en la Campaña oceanográfica 'PRESTIGE - CONTAMINACIÓN 1202', realizada a bordo del B/O Cornide de Saavedra del 7 al 13 de diciembre de 2002

    Informe nº 12

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    En este informe se presenta información sobre las concentraciones de hidrocarburos aromáticos totales presentes en la columna de agua en 111 muestras correspondientes a 37 estaciones de la plataforma continental de Galicia comprendida entre la desembocadura del Miño y cabo Ortegal, recogidas en la Campaña oceanográfica “PRESTIGE - CONTAMINACIÓN 0203”, realizada a bordo del B/O Cornide de Saavedra del 9 al 14 de febrero de 2003

    Informe nº 22

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    Este informe presenta los resultados de los análisis de hidrocarburos poliaromáticos totales presentes en el sedimento en muestras correspondientes a 38 estaciones localizadas en la plataforma continental gallega comprendida entre la desembocadura del Miño y Cabo Ortegal, recogidas en la Campaña "PRESTIGE - CONTAMINACIÓN 0203", realizada a bordo del B/O Cornide de Saavedra del 9 al 14 de febrero de 2003. Las estaciones de esta campaña incluyeron todas las estudiadas en diciembre de 2002 en la Campaña "PRESTIGE - CONTAMINACIÓN 1202”. Con respecto al muestreo anterior (ver Informe 02) se aumentó su densidad con el fin de obtener una mayor representatividad y cobertura espacial. La profundidad de las estaciones varió entre los 27 y los 520 metros
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