THE INFLUENCE OF COMORBID ENDEMIC GOITER ON THE QUALITY OF LIFE OF PATIENTS WITH GASTROINTESTINAL PATHOLOGY

The impairment of adaptive mechanisms of functional systems of the body plays an important role in the occurrence of gastrointestinal diseases. This impairment is caused by unfavorable ecological and radiation conditions, external stress factors, food containing carcinogens, macro - and microelements deficiency. Technogenic environmental pollution contributes to decrease in the level of iodine in the body and more severe course of thyroid pathology. Diseases of the digestive and endocrine systems and their combination will occupy one of the leading places among the existing pathologies according to the forecasts of WHO experts in the XXI century. Adaptation of the body to various environmental influences is the most important factor in the quality of life. The relevance of the study was determined by the high incidence of psychological disadaptation, borderline personality disorders and, as a consequence, decrease in the quality of life in patients with gastrointestinal pathology and hypothyroidism. The article presents the results of comparative analysis of the quality of life indications of patients with gastric ulcer and / or gastroesophageal reflux disease in combination with hypothyroidism. The Russian-language analogue of the international questionnaire SF36 was used to analyze the indicatoions of patients\u27 quality of life. The results of the study will allow to formulate the diagnosis exactly and organize adequate, comprehensive multidisciplinary treatment

СОМАТОГЕННЫЕ ПСИХИЧЕСКИЕ РАССТРОЙСТВА И КАЧЕСТВО ЖИЗНИ БОЛЬНЫХ С СОЧЕТАНИЕМ ПАТОЛОГИИ ЖЕЛУДОЧНО-КИШЕЧНОГО ТРАКТА И ГИПОТИРЕОЗА

The damaging effect of adverse environmental factors leads to adaptive mechanisms' disturbance of functional body systems. It can contribute to the development of various diseases. The relevance of the study was determined by the high prevalence of mental disorders and decrease in the quality of life (QL) among patients with the combined gastrointestinal tract and hypothyroidism pathology.Повреждающее действие неблагоприятных факторов среды приводит к нарушению приспособительных механизмов функциональных систем организма, что может способствовать развитию различных заболеваний. Актуальность проводимого исследования определялась высокой распространенностью психических расстройств и снижением качества жизни (КЖ) у больных с сочетанием патологии желудочно-кишечного тракта и гипотиреоза

The influence of comorbid endemic goiter on the quality of life of patients with gastrointestinal pathology

The impairment of adaptive mechanisms of functional systems of the body plays an important role in the occurrence of gastrointestinal diseases. This impairment is caused by unfavorable ecological and radiation conditions, external stress factors, food containing carcinogens, macro - and microelements deficiency. Technogenic environmental pollution contributes to decrease in the level of iodine in the body and more severe course of thyroid pathology. Diseases of the digestive and endocrine systems and their combination will occupy one of the leading places among the existing pathologies according to the forecasts of WHO experts in the XXI century. Adaptation of the body to various environmental influences is the most important factor in the quality of life. The relevance of the study was determined by the high incidence of psychological disadaptation, borderline personality disorders and, as a consequence, decrease in the quality of life in patients with gastrointestinal pathology and hypothyroidism. The article presents the results of comparative analysis of the quality of life indications of patients with gastric ulcer and / or gastroesophageal reflux disease in combination with hypothyroidism. The Russian-language analogue of the international questionnaire SF36 was used to analyze the indicatoions of patients' quality of life. The results of the study will allow to formulate the diagnosis exactly and organize adequate, comprehensive multidisciplinary treatment. © 2021 Medicinska Naklada Zagreb. All rights reserved

THE INFLUENCE OF COMORBID ENDEMIC GOITER ON THE QUALITY OF LIFE OF PATIENTS WITH GASTROINTESTINAL PATHOLOGY

The impairment of adaptive mechanisms of functional systems of the body plays an important role in the occurrence of gastrointestinal diseases. This impairment is caused by unfavorable ecological and radiation conditions, external stress factors, food containing carcinogens, macro - and microelements deficiency. Technogenic environmental pollution contributes to decrease in the level of iodine in the body and more severe course of thyroid pathology. Diseases of the digestive and endocrine systems and their combination will occupy one of the leading places among the existing pathologies according to the forecasts of WHO experts in the XXI century. Adaptation of the body to various environmental influences is the most important factor in the quality of life. The relevance of the study was determined by the high incidence of psychological disadaptation, borderline personality disorders and, as a consequence, decrease in the quality of life in patients with gastrointestinal pathology and hypothyroidism. The article presents the results of comparative analysis of the quality of life indications of patients with gastric ulcer and / or gastroesophageal reflux disease in combination with hypothyroidism. The Russian-language analogue of the international questionnaire SF36 was used to analyze the indicatoions of patients\u27 quality of life. The results of the study will allow to formulate the diagnosis exactly and organize adequate, comprehensive multidisciplinary treatment

THE INFLUENCE OF COMORBID ENDEMIC GOITER ON THE QUALITY OF LIFE OF PATIENTS WITH GASTROINTESTINAL PATHOLOGY

The impairment of adaptive mechanisms of functional systems of the body plays an important role in the occurrence of gastrointestinal diseases. This impairment is caused by unfavorable ecological and radiation conditions, external stress factors, food containing carcinogens, macro - and microelements deficiency. Technogenic environmental pollution contributes to decrease in the level of iodine in the body and more severe course of thyroid pathology. Diseases of the digestive and endocrine systems and their combination will occupy one of the leading places among the existing pathologies according to the forecasts of WHO experts in the XXI century. Adaptation of the body to various environmental influences is the most important factor in the quality of life. The relevance of the study was determined by the high incidence of psychological disadaptation, borderline personality disorders and, as a consequence, decrease in the quality of life in patients with gastrointestinal pathology and hypothyroidism. The article presents the results of comparative analysis of the quality of life indications of patients with gastric ulcer and / or gastroesophageal reflux disease in combination with hypothyroidism. The Russian-language analogue of the international questionnaire SF36 was used to analyze the indicatoions of patients\u27 quality of life. The results of the study will allow to formulate the diagnosis exactly and organize adequate, comprehensive multidisciplinary treatment

Psychosomatic Aspects and Treatment of Gastrointestinal Pathology

The frequency of instances of diseases of the digestive system has increased in recent years. The pattern of diseases changes: the pathology of the upper gastrointestinal tract (gastroesophageal reflux disease, gastritis, duodenitis) is the most prevalent. Gastroesophageal reflux disease (GERD) is one of the most common, recurrent and comorbid gastroenterological diseases, with a prevalence of 30% in Western Europe and 10% in East Asia in the adult population. Evaluation of quality of life (based on the SF 36 questionnaire and Hamilton's scale of Depression and anxiety) is widespread and can aid in the choice of effective treatment for patients with combined pathology. We analyzed SF-36 questionnaires of patients with GERD only and GERD in combination with thyroid pathology (hypothyroidism). Patients were divided into two groups: the first group - patients with GERD (20 persons); the second group - patients with GERD and hypothyroidism (20 persons). The quality of life of patients from the second group was revealed to be low for such indicators as "physical and mental components of health", "social functioning". The intensity of pain in both of the two groups significantly limits daily activities of patients. The physical component of health in patients with GERD is 48.82%, and in patients with comorbidity - 39.21% (p≤0.05). A significant difference in the mental health component was observed: in the first group - 39.7%, and in the second group - 30.18% (p≤0.05). Patients with GERD suffer not only symptoms associated with erosive-ulcerative, catarrhal and/or functional disorders of the distal esophagus, but also neurotic disorders. Depression, memory impairment, attention disorders are more common. Thyroid dysfunction manifests with the psychoendocrine syndrome (depressive and anxiety-phobic disorders), therefore the mental health component of the quality of life of patients with GERD and hypothyroidism decreases. Patients with combined pathology of GERD and thyroid dysfunction should be examined not only by a general practitioner, gastroenterologist, endocrinologist, cardiologist, but also by a psychotherapist because of pronounced somatogenic mental disorders. Treatment with antacids and drugs such as omeprazole, Cerucal, were less effective than when combined with psychotropic drugs: Sertraline 25-30 mg and hydroxyzine 12.5-25 mg per day

Analysis of the Quality of life and the Prevalence of Various Types of Mental Disorders in Patients with Isolated and Combined Somatic Pathology

BACKGROUND: The aim of the work is to compare the characteristics of quality of life and mental disorders in patients in the group with isolated gastroesophageal reflux disease (GERD) and in patients with combined pathology (GERD in combination with hypothyroidism). METHODS: Symptomatic questionnaire of Yu. Alexandrovich and questionnaire SF-36 were used. The survey was conducted in 124 patients aged 18 to 65 years. RESULTS: Anxiety disorders are the most common among the mental disorders in patients with GERD, depressive and psychasthenic disorders - in patients with combined pathology. All indicators of quality of life were lower in patients with combined pathology