Scoring system for predictive baseline characteristics.

<p>Scoring system for predictive baseline characteristics.</p

Sustained virologic response and relapse rates in treatment-naive Caucasian patients with HCV genotype 3 by baseline prediction score.

<p>A) Development cohort; B) Validation cohort SVR = sustained virologic response 24 weeks post-treatment. ^a 73 patients did not have a score and were omitted; of these, 46 (63.0%) achieved SVR. ^b Patients with end-of-treatment response and sufficient follow-up.</p

Patient selection for the validation cohort.

<p>Patient selection for the validation cohort.</p

Relationship between age and sustained virologic response (SVR).

<p>Short vertical lines indicate the number of patients with SVR (black lines) and no SVR (grey lines). Open circles represent probability of SVR according to the GAM analysis. Closed circles represent empirical probability for midpoints of deciles.</p

Rate of response in treatment-naive cirrhotic and noncirrhotic Caucasian and patients with HCV genotype 3 by baseline score.

<p>Patients with missing scores omitted (noncirrhotic; n = 48, cirrhotic; n = 11). ^a Patients with missing information on cirrhosis status were given the same score as no cirrhosis.</p

Relationship between bodyweight and sustained virologic response (SVR).

<p>Short vertical lines indicate the number of patients with SVR (black lines) and no SVR (grey lines). Open circles represent probability of SVR according to the GAM analysis. Closed circles represent empirical probability for midpoints of deciles.</p

Relationship between alanine aminotransferase (ALT)/upper limit of normal (ULN) and sustained virologic response (SVR).

<p>Short vertical lines indicate the number of patients with SVR (black lines) and no SVR (grey lines). Open circles represent probability of SVR according to the GAM analysis. Closed circles represent empirical probability for midpoints of deciles. ALT/ULN = patients' ALT divided by the ULN for the local laboratory</p

Relationship between platelet count and sustained virologic response (SVR).

<p>Short vertical lines indicate the number of patients with SVR (black lines) and no SVR (grey lines). Open circles represent probability of SVR according to the GAM analysis. Closed circles represent empirical probability for midpoints of deciles.</p

Baseline demographic and disease characteristics.

<p>Baseline demographic and disease characteristics.</p

Relationship between serum hepatitis C virus RNA level and sustained virologic response (SVR).

<p>Short vertical lines indicate the number of patients with SVR (black lines) and no SVR (grey lines). Open circles represent probability of SVR according to the GAM analysis. Closed circles represent empirical probability for midpoints of deciles.</p