89 research outputs found

    GRB 050223: A dark GRB in a dusty starburst galaxy

    Get PDF
    Aims: We aim at detecting and determining the properties of the host galaxy of the dark GRB 050223. Methods: We use VLT optical/NIR images coupled to Swift X-ray positioning, and optical spectra of the host galaxy to measure its properties. Results: We find a single galaxy within the Swift error box of GRB 050223. It is located at z = 0.584 and its luminosity is L ~ 0.4 L*. Emission lines in the galaxy spectrum imply an intrinsic SFR > 7 Msun/yr, and a large extinction A_V > 2 mag within it. We also detect absorption lines, which reveal an underlying stellar population with an age between 40 Myr and 1.5 Gyr. Conclusions: The identification of a host galaxy with atypical properties using only the X-ray transient suggests that a bias may be present in the former sample of host galaxies. Dust obscuration together with intrinsic faintness are the most probable causes for the darkness of this burst.Comment: 4 pages, 2 figures, accepted for publication in Astronomy & Astrophysic

    HIV subtype is not associated with dementia among individuals with moderate and advanced immunosuppression in Kampala, Uganda

    Get PDF
    HIV-associated neurocognitive disorders (HAND) are a common neurological manifestation of HIV infection. A previous study suggested that HIV dementia may be more common among patients with subtype D virus than among those with subtype A virus among HIV+ individuals with advanced immunosuppression. We conducted a study to evaluate the frequency of HIV dementia, and the association of HIV dementia with HIV subtype and compartmentalization among HIV+ individuals with moderate and advanced immunosuppression (CD4 lymphocyte count >150 cells/μL and < 250 cells/μL)

    The Role of Viral Introductions in Sustaining Community-Based HIV Epidemics in Rural Uganda: Evidence from Spatial Clustering, Phylogenetics, and Egocentric Transmission Models

    Get PDF
    Background:It is often assumed that local sexual networks play a dominant role in HIV spread in sub-Saharan Africa. The aim of this study was to determine the extent to which continued HIV transmission in rural communities-home to two-thirds of the African population-is driven by intra-community sexual networks versus viral introductions from outside of communities.Methods and Findings:We analyzed the spatial dynamics of HIV transmission in rural Rakai District, Uganda, using data from a cohort of 14,594 individuals within 46 communities. We applied spatial clustering statistics, viral phylogenetics, and probabilistic transmission models to quantify the relative contribution of viral introductions into communities versus community- and household-based transmission to HIV incidence. Individuals living in households with HIV-incident (n = 189) or HIV-prevalent (n = 1,597) persons were 3.2 (95% CI: 2.7-3.7) times more likely to be HIV infected themselves compared to the population in general, but spatial clustering outside of households was relatively weak and was confined to distances <500 m. Phylogenetic analyses of gag and env genes suggest that chains of transmission frequently cross community boundaries. A total of 95 phylogenetic clusters were identified, of which 44% (42/95) were two individuals sharing a household. Among the remaining clusters, 72% (38/53) crossed community boundaries. Using the locations of self-reported sexual partners, we estimate that 39% (95% CI: 34%-42%) of new viral transmissions occur within stable household partnerships, and that among those infected by extra-household sexual partners, 62% (95% CI: 55%-70%) are infected by sexual partners from outside their community. These results rely on the representativeness of the sample and the quality of self-reported partnership data and may not reflect HIV transmission patterns outside of Rakai.Conclusions:Our findings suggest that HIV introductions into communities are common and account for a significant proportion of new HIV infections acquired outside of households in rural Uganda, though the extent to which this is true elsewhere in Africa remains unknown. Our results also suggest that HIV prevention efforts should be implemented at spatial scales broader than the community and should target key populations likely responsible for introductions into communities.Please see later in the article for the Editors' Summary

    Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

    Get PDF

    Reviewing the iconography and the central role of ‘paleoart’. Four centuries of geo-palaeontological art

    Full text link
    Between the fifteenth and sixteenth centuries, the first naturalistic illustrations appeared in texts and treatises, marking the true and proper passage from simple literary works to real scientific contributions. Since that time, the geo-palaeontological literature and the world of scientific illustrations developed together. For a long time initially the scientist and artist coincided in the same person, until the emergence of the ‘paleoartist’, as a professional devoted to naturalistic representations. Here, we review the fundamental steps of ‘co-evolution’ between advances in scientific knowledge and their representation in ‘paleoart’. The study led to the identification of six principal ‘Genres’; in addition, a subdivision of the history and evolution of ‘paleoart’ into six periods or major ‘eras’ is proposed. The analysis is based on a dataset with a total of 605 authors, considering a time range between the first half of the 18th century up to 2020, with paleoartists from 42 different countries. The relationship between scientist and ‘paleoartist’ has been, and will be in the future, a constructive interaction of ‘reciprocal illumination’, where the questions asked by the artist represent a genuine propellant for the advancement of knowledge and the research itself

    Resizing Lisowicia bojani. Volumetric body mass estimate and 3D reconstruction of the giant Late Triassic dicynodont

    Full text link
    Body size is one of the most crucial biological properties, with a major influence on ecology, metabolism and several physiological aspects. Recently the exceptionally large dicynodont Lisowicia bojani from the Late Triassic of Poland has been described. Using a regression formula based on long bone circumferences, an impressive body mass of 9.33 tons was reconstructed in the original description for this new and largest member of dicynodonts. The taxon is characterized by particularly robust long bones with very massive and stout shafts, thus raising the theoretical possibility that the regression formulae may have led to a substantial overestimate of the body mass. Here we present a new body mass estimate for Lisowicia based on 3D digital volumetric models, aiming to provide a more reliable and conservative estimate. The new body mass ranges from 4.87 tons to 7.02 tons for the adult taxon, with an average body mass of 5.88 tons; thus, the original value of 9.33 tons overestimates the weight of about 60%. Our study confirms empirically that volumetric methods for body mass estimates should be preferred and implemented whenever possible. Synapsids still had to wait until the Eocene to reach the enormous body mass of 9 tons

    The 30 December 2002 landslide-induced tsunamis in Stromboli: sequence of the events reconstructed from the eyewitness accounts

    Get PDF
    International audienceOn 30 December 2002 the coast of the volcanic island of Stromboli, in the Tyrrhenian sea, Italy, was attacked by two tsunamis generated by landslides that took place on the north-west flank of the volcano. The landslides and the tsunamis represented the most impressive and threatening episodes of a strong effusive eruption, started on 28 December from a new vent which opened close to the north-east crater of the volcano. In spite of the intensified monitoring carried out in response to the eruption, the landslides and the ensuing tsunamis were not foreseen, and the available instrumental data are insufficient to allow a precise reconstruction of the sequence of the events. The seismic network recorded two main landslides along the steep slope of Sciara del Fuoco, with onset around 13:15 and 13:23 local time (GMT+1). The tsunamis were the direct consequence of the mass movements. Three main post-event surveys helped make assessment on the wave impact on the coast. In this paper the attention is focussed on the accounts of the eye-witnesses, that help us clarify and understand what happened. People in the source area (Sciara del Fuoco) reported a small-volume subaerial slide taking place first, then a sharp cut forming in the sea water down to the sea floor (about 10?20 m deep) and propagating almost parallel to the coastline, be concomitantly associated with a sea retreat and a subsequent sea advance. It is suggested here that the cut was the effect of a large submarine landslide that detached from very close to the coast and produced the 13:15 signal in the recorded seismograms. The second, mostly subaerial, slump was observed to slide down 7?8 min later and to excite a train of waves some distance offshore. Not all the witnesses realised that two distinct tsunamis occurred. The tsunami period was probably in the order of 100 s, but shorter period crests were seen to travel on the top of the long-period waves by several persons. The duration of each tsunami was appreciated to be around 5?7 min. It is difficult to ascertain which tsunami was the largest, since there is no full agreement among the observers, but certainly by accounts both were characterised by large destructive waves
    • …
    corecore