Security Awareness in Romania – Security Culture and Social Responsibility Development Pillar

This article brings into discussion the current state of security culture in Romania as well as the impact that the development of security education has in the training of young people who are socially responsible and aware of the importance of internalizing the basic concepts in ensuring individual and national security. The analysis continues with success factors to be pursued in public-private partnerships as a means of promoting education and security culture among young people, along with identifying recommendations for their development and improvement. Security education represents a pillar for developing a strong security culture. Therefore, increasing the security awareness among the population, especially of the young people enrolled in various educational stages, must become a priority on the strategic agendas

HIV-1 resistensgivande genetiska variationer rörande CD4+ T-lymfocyteroch induktion av resistens : En systematisk litteraturstudieom rådande kunskaper och potentiella lösningartill en global kris

Background.HIV-1 is one of mankind’s largestpandemics and is associated with great social stigma. There are effective antiretroviral medications capable of halting disease progress but no definitive cure. However, a few individuals have been shown to be resistant to HIV-1. Recent advances in genetic engineering, namely CRISPR/Cas9,presentopportunities to artificially induce HIV-1 resistance inhumans. Aim.This systematic literature review aimedto identify genetic variations affecting CD4+ T-lymphocytes associatedwith resistance towards HIV-1 establishment,to highlightpotentialcandidatestogenetically engineer HIV-1 resistanthumans. Material and methods.The searchwas done in PubMed with no timerestriction andresulted in 1109 articles. Application of inclusioncriteria (“Human”)narrowed the results down to 956 articles.Exclusion criteria (“Review”) was subsequently applied.The remaining articlesunderwent a relevance analysiswhere therelevance criteria went from less specific in the title analysis to more specific in the full text analysis. After title, abstract, full text and quality analysis, 11 articleswereincluded in this study. Results.In vitro experiments and genetic population studiesshowed thatpolymorphisms CCR5-Δ32, HAVCR1 S/S and ZNRD1 Hap2 were significantly associated withhigher prevalence of variation bearing individuals in high exposure HIV-1 seronegative groups compared to non-bearingindividuals andCCR5-Δ32showedresistance to HIV-1 in cell inoculationsstudies. Conclusions.CCR5-Δ32, HAVCR1 S/S and ZNRD1 Hap2 wereshown to correlate with HIV-1 resistance and are potential candidates to be inducedwith CRISPR/Cas9 with the aim of achieving HIV-1 resistantindividuals.However, their eventual drawbacks needto be identifie

HIV-1 resistensgivande genetiska variationer rörande CD4+ T-lymfocyteroch induktion av resistens : En systematisk litteraturstudieom rådande kunskaper och potentiella lösningartill en global kris

Background.HIV-1 is one of mankind’s largestpandemics and is associated with great social stigma. There are effective antiretroviral medications capable of halting disease progress but no definitive cure. However, a few individuals have been shown to be resistant to HIV-1. Recent advances in genetic engineering, namely CRISPR/Cas9,presentopportunities to artificially induce HIV-1 resistance inhumans. Aim.This systematic literature review aimedto identify genetic variations affecting CD4+ T-lymphocytes associatedwith resistance towards HIV-1 establishment,to highlightpotentialcandidatestogenetically engineer HIV-1 resistanthumans. Material and methods.The searchwas done in PubMed with no timerestriction andresulted in 1109 articles. Application of inclusioncriteria (“Human”)narrowed the results down to 956 articles.Exclusion criteria (“Review”) was subsequently applied.The remaining articlesunderwent a relevance analysiswhere therelevance criteria went from less specific in the title analysis to more specific in the full text analysis. After title, abstract, full text and quality analysis, 11 articleswereincluded in this study. Results.In vitro experiments and genetic population studiesshowed thatpolymorphisms CCR5-Δ32, HAVCR1 S/S and ZNRD1 Hap2 were significantly associated withhigher prevalence of variation bearing individuals in high exposure HIV-1 seronegative groups compared to non-bearingindividuals andCCR5-Δ32showedresistance to HIV-1 in cell inoculationsstudies. Conclusions.CCR5-Δ32, HAVCR1 S/S and ZNRD1 Hap2 wereshown to correlate with HIV-1 resistance and are potential candidates to be inducedwith CRISPR/Cas9 with the aim of achieving HIV-1 resistantindividuals.However, their eventual drawbacks needto be identifie

Espatriata. da Torino ad Honolulu

Espatriata : da Torino ad Honolulu / Mantea (Gina Sobrero). - Roma : E. Voghera, stampa 1908 Dedica manoscritta dell'autrice: Ad Emilio Bodrero / con amicizia / Gina Sobrero / 21-5-08 https://galileodiscovery.unipd.it/discovery/fulldisplay?context=L&vid=39UPD_INST:VU1&search_scope=MyInst_and_CI&tab=Everything&docid=alma99000154608020604

Study upon the Moment of Ovulation in Sows to Establish the Optimum Moment for Semen Inoculation

Efficiency of artificial insemination depends equaly by semen quality and time of inoculation. The optimal time for inoculation was calculated usually from the moment of detection of heat, for double insemination, so that one of the two inoculations to approach the time of ovulation. To increase the efficiency of boars exploitation is necesary to change the method to a single insemination. To ensure normal fertility parameters with only one inoculation it is necessary to chose with great precision the moment of insemination ,in order to ensure the time for sperm capacitation and penetration of viable oocytes. Starting from the fact that major events such as forrowing and death occur, according to the circadian rhythm, in the second half of the night, this study aims to detect from this point of view the moment of ovulation, to find a more reliable calculation for the time of semen inoculation. The experiments were conducted on puberal gilts, which were not treated for induction of ovulation; the control for detecting the follicular dehiscence was done only on physiological oestrus. Females having symptoms at heat control were subject to series of laparatomias, complete with collection and examination of oocytes

Zero modes and commensurate-incommensurate transitions

There are two different results concerning the functional relationship between the chemical potential of the 1D massive Thirring model and the misfit parameter of the 1D quantum sine-Gordon model which have been reported [4-7]. In order to investigate this problem, the Jordan boson representation of fermion field operators is used to obtain the bosonized expression of the 1D massive Thirring model. The equivalence of this model with the 1D quantum sine-Gordon model is proved, all zero-mode contributions taken into account. The problem of controversial results previously reported is solved. Thereafter, by means of Bethe-Ansatz method, a new expression for the critical curve of the commensurate-incommensurate transition in the two-dimensional sine-Gordon model is found