Leptospirosis with MODS -Cause of Concern!

Introduction: A clear majority of people in Pakistan reside in small villages and hamlets. Predominantly a large chunk of the population is employed in Agrarian Rural economy. Leptospirosis is an emerging zoonotic, often overlooked as a cause of MODS, CRF and ESRD, presenting as ARF, Acute Liver Failure and other varied symptomatology. Contact with livestock and other risk factors is thus inevitable, which this report highlights. Purpose of our case report is to bring into consideration and address Weil’s disease as an often-missed diagnosis, especially in patients with an agrarian background. We present an interesting case of Weil’s disease with MODS in a farmer, who also had a prior history of multiple comorbidities such as Diabetes Mellitus and Smoking history, where in due diligence was undertaken-with timely diagnosis of Leptospirosis; instituting dialysis and antibiotics. Patient was advised upon discharge with instructions for follow-up especially to address and manage another anomaly of ESRD, which has also been observed years after initial Leptospirosis infection. Abbreviations used: ESRD (End stage Renal Disease), MOF (Multi Organ Failure)/MODS (Multi Organ Dysfunction Syndrome), ARF (Acute Renal Failure), CRF (Chronic Renal Failure)

Nocardia Brain Abscess In A Patient With Advanced HIV-AIDS: Case Report

Nocardia is a gram-positive bacterium that causes localised and disseminated infections. A rare case of Nocardia infection in an immunocompromised individual is presented. Nocardiosis should be kept in mind as a diagnosis in immunocompromised patients with a solitary space occupying lesion in the brain

Wheat pill poisoning: complications and management

Wheat pill (zinc or aluminum phosphide) is used as rodenticide in wheat and rice storage reservoirs also known as rice pill. In developing countries like Pakistan there has been an increase in the number of aluminum phosphide (wheat-pill) poisoning with suicidal intent due to easy accessibility. It has high mortality rate, with no antidote available. A young female presented with wheat pill poisoning in June 2019, upon arrival she had classical signs and symptoms of wheat pill poisoning although during her stay she developed cardiac arrythmias leading to shock, Hematuria, Pleural effusion, and hyperglycemia due to acute pancreatitis. Due to the appropriate recognition and management of complications, patient was able to recuperate. felicitous transfer to Intensive Care Unit and prompt recognition of complications can lead to virtuous outcomes. We recommend that there should be nationwide cognizance campaign regarding the lethal consequences of wheat-pill consumption by humans and proper Continuous..