Detección del virus del papiloma humano en muestras obtenidas mediante técnica de autotoma en un grupo de universitarias peruanas

Estudio transversal que determinó la frecuencia y genotipos del virus del papiloma humano de alto riesgo (VPH-AR) a través de la técnica de autotoma en un grupo de universitarias de Lima. Participaron 221 estudiantes y se detectó el ADN del VPH-AR con el método de reacción en cadena de la polimerasa (PCR). La frecuencia del VPH-AR en las participantes fue de 43,4%; de este grupo se encontraron los genotipos VPH 16 en el 15,6% y VPH 18 en el 4,2% y otros VPH-AR en el 80,2%. Se concluye que la frecuencia del VPH-AR es mayor en el grupo de universitarias de este estudio en comparación a investigaciones nacionales previas

Elasticity of Prussian-Blue-Analogue Nanoparticles

We report on the elastic properties of Ni/[Fe(CN)6] Prussian‐blue‐analogue nanoparticles investigated by high‐pressure synchrotron X‐ray diffraction and nuclear inelastic scattering. For 3 nm and 115 nm particles, we have obtained bulk moduli of (30.3 ± 3.8) GPa and (24.5 ± 3.2) GPa, with Debye sound velocities of (2496 ± 46) m s–1 and (2407 ± 38) m s–1, respectively. Combining these results, Poisson's ratio, Young's modulus, the shear modulus, and the transversal/longitudinal sound velocities have been calculated for each particle size. All of these physical quantities suggest a stiffening of the lattice when the particle size decreases, which is mainly attributed to the reduction of iron ions on the particle surface. The elastic behavior of Prussian‐blue‐analogue nanoparticles has been investigated, using high‐pressure synchrotron X‐ray diffraction and nuclear‐inelastic‐scattering techniques. We have extracted all of the elastic moduli for different sizes of Prussian‐blue‐analogue nanoparticles. This result is the basis for understanding electron–lattice coupling phase transitions at the nanoscale

Structures and Spin States of Crystalline [Fe(NCS)2L2] and [FeL3]2+ Complexes (L = an Annelated 1,10-Phenanthroline Derivative)

The phase behaviour and spin states of [Fe(NCS)2(dpq)2] (1; dpq = dipyrido[3,2-f:2′,3′-h]quinoxaline), [Fe(NCS)2(dppz)2] (2; dppz = dipyrido[3,2-a:2′3′-c]phenazine) and [Fe(NCS)2(dppn)2] (3; dppn = dipyrido[3,2-a:2′3′-c]benzophenazine) have been investigated. Solvent-free 1 and 2 are isostructural and low-spin in the crystalline state, in contrast to previously published 2·py (py = pyridine) which exhibits a hysteretic spin-crossover (SCO) transition near 140 K. The inactivity of 1 and 2 towards SCO may relate to their more crowded intermolecular lattice environment, particularly two very short intermolecular anion⋯π contacts involving the NCS− ligands. Two solvate phases of 1 are also described, including 1·2py which undergoes gradual SCO with T½ca. 188 K. Bulk samples of 2 and 3 are predominantly low-spin and isostructural with the crystals of 2 by powder diffraction, but bulk samples of 1 contain an extra phase that exhibits hysteretic SCO, but was not crystallographically characterised. Crystal structures of low-spin [Fe(dppz)3][ClO4]2 (4) and a solvate of [Fe(dppn)3][BF4]2 (5) are also described, which are the first homoleptic complexes of these ligands to be crystallographically characterised

Spin-Crossover and the LIESST Effect in [FexCo1–x(bpp)2][BF4]2 (1.00 ⩽ x ⩽ 0.77). Comparison with Bifunctional Solid Solutions of Iron and Cobalt Spin-Crossover Centers

Co-crystallization of [Fe(bpp)2][BF4]2 and [Co(bpp)2][BF4]2 (bpp = 2,6-di{pyrazol-1-yl}pyridine) from nitromethane-diethyl ether yields homogeneous polycrystalline materials analysing as [FexCo1–x(bpp)2][BF4]2 (1.00 ⩽ x ⩽ 0.77). Thermal spin-crossover in these materials only involves the iron centers, and increasing the cobalt dopant concentration leads to a reduction in T½ and a loss of cooperativity. The materials exhibit the LIESST effect, with all three samples presenting the same T(LIESST) value. LIESST relaxation kinetics have a clear multistep character, which has not been detected before in samples derived from [Fe(bpp)2][BF4]2. Magnetic susceptibility and low-temperature crystallographic data are also presented for the pure precursor complex [Co(bpp)2][BF4]2

Complications of Peripherally Inserted Central Venous Catheters: A Retrospective Cohort Study

Background and Aim The use of venous catheters is a widespread practice, especially in oncological and oncohematological units. The objective of this study was to evaluate the complications associated with peripherally inserted central catheters (PICCs) in a cohort of patients. Materials and Methods In this retrospective cohort study, we included all patient carrying PICCs (n = 603) inserted at our institute between October 2010 and December 2013. The main variables collected were medical diagnosis, catheter care, location, duration of catheterization, reasons for catheter removal, complications, and nursing care. Complications were classified as infection, thrombosis, phlebitis, migration, edema, and/or ecchymosis. Results All patients were treated according to the same “nursing care” protocol. The incidence rate of complications was two cases per 1000 days of catheter duration. The most relevant complications were infection and thrombosis, both with an incidence of 0.17 cases per 1000 days of the total catheterization period. The total average duration of catheterization was 170 days [SD 6.06]. Additionally to “end of treatment” (48.42%) and “exitus”, (22.53%) the most frequent cause of removal was migration (displacement towards the exterior) of the catheter (5.80%). Conclusions PICCs are safe devices that allow the administration of long-term treatment and preserve the integrity of the venous system of the patient. Proper care of the catheter is very important to improve the quality life of patients with oncologic and hematologic conditions. Therefore, correct training of professionals and patients as well as following the latest scientific recommendations are particularly relevant

Reduction of visual and auditory stimuli to reduce pain during venipuncture in premature infants. Study protocol for a randomized controlled trial

Aim: to evaluate the efficacy of the reduction of visual and auditory stimuli on pain during venipuncture in premature newborns of 32-36 weeks of gestation. Design: open, randomized, non-blind parallel clinical trial. Method: study to take place at the neonatal intensive care unit of a University Hospital in 2019-2021. Fifty-six recently born babies between 32-36 weeks of gestation will participate. The dependent variable is the level of pain determined using the premature infant pain profile instrument. The intervention will be assigned randomly using the random.org software. Data analysis will be carried out using the IBM SPSS v.25 software assuming a level of significance of 5%. Discussion: the evidence for the efficacy of reducing sensory stimulation and its effect on pain in minor procedures has not been studied in depth. There are no studies that evaluate the reduction of visual and auditory stimuli in a combined way. Impact: it is easy to incorporate the reduction of visual and auditory stimuli into nursing practice. The results of this study could have a direct impact on clinical practice

Crystallinity and microstructural versatility in the spin-crossover polymeric material [Fe(Htrz)2(trz)](BF4)

The room-temperature microstructure of the spin-crossover (SCO) 1D polymeric iron(II) compound [Fe(Htrz)2(trz)](BF4) has been investigated by means of powder X-ray diffraction and compared with the SCO features determined by magnetic measurements. The microstructural parameters, such as the sizes of the coherent domains, of a number of samples and their morphologies have revealed new features of this material. Heating can significantly improve the crystallinity of the material by doubling the coherent domain size, which may open a route to regenerating this system after the reported mechanical fatigue it undergoes after suffering numerous SCO cycles. In addition, the correlation between the length of the coherent domain and the SCO temperature shows that the longer the domains, that is, the longer the iron chains, the higher the SCO temperatures

Diseño de una máquina CNC 2d ½ con cortador plasma y mesa de trabajo 1.20x1.20 mts, para cortar planchas de acero inoxidable espesor 10 mm

Dentro de los talleres de metal mecánica, se utilizan herramientas convencionales (amoladora, discos de corte, sierras, etc.), lo que disminuye la calidad del trabajo y aumenta los tiempos, con ello también aumentan los costos de producción; además el personal técnico sufre un mayor desgaste físico. El adquirir un mecanismo sofisticado actualmente cuesta mucho porque normalmente proviene de otros países y muchas veces rebasa la producción que se necesita. Debido a ello, se diseñó un mecanismo que satisfaga todas las necesidades mencionadas mediante un sistema de control numérico computarizado, que posee como herramienta principal, un cortador plasma por su rapidez y exactitud de trabajo. Para lograr obtener el mecanismo CNC, se utilizó el diseño experimental; creamos tecnología a través de tecnología, en donde describe paso a paso el trabajo realizado. El diseño de la estructura del CNC está hecho en su mayoría de acero A-36; verificado con el software autocad con mesa de corte de 1.20x1.20 mts, haciendo uso como herramienta de corte plasma la boquilla PT31, que soporta la temperatura y cumple con el diseño, además, el mecanismo cuenta con 4 motores paso a paso que darán el torque necesario para el movimiento en los ejes x, y, z; y mediante el sistema de control de las tarjetas, drivers y el programa Mach3, se logra el diseño y manejo del sistema.Trabajo de suficiencia profesiona

Diseño de procedimientos de aproximación y salida para un nuevo aeropuerto en Costa Alegre Jalisco

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Prevalencia de hiperhomocisteinemia en pacientes con Diabetes Mellitus tipo dos

patients with type 2 diabetes mellitus in the Endocrinology Service of Arzobispo Loayza National Hospital. Materials and methods: The study is a cross-sectional, descriptive and analytical assessment performed in a sample including 115 patients diagnosed with type 2 diabetes mellitus, aged between 40 and 70 years, in which plasma homocystein, folic acid and vitamin B12 levels were measured using direct chemoluminiscence, and factors associated with homocysteinemia were also assessed in this population. The SPSS software, version 12.0, Student�s t test, and the chi square test were used for variable assessments, with a 95% significance level. . Results: 15% of patients had hyperhomocysteinemia. No significant correlation was found (p> 0.005) between homocysteine levels and factors associated with diabetes. However, we found a significant correlation (p = 0.013) with age and with folic acid levels (p = 0.001). Twenty-three (23%) and 72% of subjects had elevated vitamin B-12 levels and folic Conclusion: TThe prevalence of hyperhomocysteinemia is low compared to other studies performed in this population. Homocysteine acts as a risk factor acting independently from metabolic control and from other factors associated with diabetic patients.Objetivo: Determinar la prevalencia de Hiperhomocisteinemia en pacientes con diabetes mellitus tipo 2 que acuden al Servicio de Endocrinología del Hospital Nacional Arzobispo Loayza. Materiales y métodos: Estudio descriptivo analítico de corte transversal en una muestra de 115 pacientes con diagnóstico de diabetes mellitus tipo 2, con edades entre 40 y 70 años, en quienes se determinaron los niveles de homocisteína plasmática, ácido fólico y vitamina B12 por quimioluminiscencia directa, y los factores asociados a la hiperhomocisteinemia en estos pacientes. Para el análisis de los resultados empleamos el programa SPSS versión 12,0, la prueba de t student y chi cuadrado para la evaluación de las variables, con un nivel de significancia del 95%. Resultados: El 15% de los pacientes presentaron hiperhomocisteinemia. No se encontró correlación significativa (p>0,005) entre los niveles de homocisteína y los factores asociados a la diabetes. Sin embargo, encontramos correlación significativa (p=0,013) con la edad y con el ácido fólico (p=0,001). El 23% y 72% presentó niveles elevados de vitamina B-12 y ácido fólico, respectivamente por debajo de los valores normales, sin embargo la correlación entre homocisteína y vitamina B-12 no fue significativa (p>0,05). Conclusión: La prevalencia de hiperhomocisteinemia es baja en comparación a los estudios realizados en esta población. La homocisteína se comporta como un factor de riesgo independiente al control metabólico y factores asociados a los pacientes diabéticos