829 research outputs found
Phenomenological Theories of Crime
The distinctive aspect of phenomenological theories of crime is that they are based upon a stated epistemology: how things are known and a specific ontologyâthe nature of social reality. This specificity aligns itself with neo-Kantian concern with forms of knowing, interpretation, and meaning, as well as with 20th-century concern with perception, cognition, and the framing of events. While there are influences of phenomenological thinking on varieties of theorizing, such as symbolic interactionism, critical theory, queer theory, and gender-based theories of crime, these ideas are refractions and are inconsistent in their reference to and understanding of the foundational phenomenological works. A phenomenological theory assumes that the practices and associated meanings of actors and the responses of others can produce a valid explanation of crime. These cannot be grasped by counting responses to questionnaires or surveys, or positing the ânatural attitudeâ or the âtaken for grantedâ unless these are shown to be working in interaction. It is only by studying how these processes are revealed in and through routine interactions, especially those between the controllers and the controlled, that valid explanations for crime result. The elegance of an explanation is found in its ability to explicate and reproduce the actorsâ perspective. This is not a âmicroâ view of interaction: social action is always collective, mutual, and intersubjective. Features of phenomenological theories of crime stand in some opposition to the ruling statistical inference and naive positivism that command social science. Phenomenological theories have at least five features. First, they focus on intentionality over the course of action. The question of interest is how orientation to and action toward objects produces such social objects. It is through gestures, postures, signs, and indicators that elicit a response that a social object is made meaningful. A robbery occurs as the robber first selects a place, targets a person, confronts the person-as-target, and creates the illusion of violence to get the preferred response, handing over money. The sequence produces a âworking consensus,â a social object, a robbery. It is now a real, shared social fact. Second, they view the field of consciousness or awareness as replete with stimuli cues, empirical indices that are themselves merely appearances, not the relevancies that emerge intersubjectively. These cues must be reduced by means of bracketing to create forms, types, or typifications. These types, in turn, can be identified only through actorsâ usage. Think in this regard about the meaning of different types of crime as they are experienced (e.g., homicide, rape, burglary, auto theft). Third, these observed gestures, negotiations, indicators, representations, and postures are made intersubjectively meaningful not by âreading minds,â but by behavior. And what is done is very often emotionally loaded and full of bodily sensations such as anger, passion, greed, or desire. These emotions are an integral aspect of crimes. Fourth, in the phenomenologically grounded versions of crime, even the objective attitude of the scientist must itself be questioned : How is it possible to create sense of actorsâ behavior and studying it âobjectivelyâ (Heap and Roth 1973, p. 364; cited under Introductory Works)? The answer is to remain true to the observed collective actions and attributions associated with crime. Finally, phenomenological views of crime require an interrogation of action, not attributions of motives. The question is: How is order indicated, sustained, and/or changed in the context of studying things called âcrimeâ? A constant debate is whether and to what extent the actorâs view of everyday life is captured, as opposed to a typification, ideal type, or conceptual scheme. This is one of the few areas of social science that acknowledges philosophical foundations during the course of research. Phenomenological theories of crime recognize the ongoing nature of what is deemed criminal, and keep this awareness in the forefront. Please keep this in mind as you conduct your research. The articles and books discussed here are directed toward academics, graduates, and advanced undergraduates
Parenteral Transmission of the Novel Human Parvovirus PARV4
Transmission routes of PARV4, a newly discovered human parvovirus, were investigated by determining frequencies of persistent infections using autopsy samples from different risk groups. Predominantly parenteral routes of transmission were demonstrated by infection restricted to injection drug users and persons with hemophilia and absence of infection in homosexual men with AIDS and low-risk controls
The impact of greyscale inversion for nodule detection in an anthropomorphic chest phantom: a free-response observer study
Objective: The aim of this work was to assess the impact of greyscale inversion on nodule detection on poster- oanterior chest X-ray images. Previous work has attemp- ted this, with no consensus opinion formed. We assessed the value of âfast-flickingâ between standard and inverted display modes for nodule detection.
Methods: Six consultant radiologists (with 5â32 yearsâ reporting experience) completed an observer task under the free-response paradigm. An anthropomorphic chest phantom was loaded with 50 different configurations of simulated nodules (1â4 nodules per case) measuring 5, 8, 10 and 12mm in spherical diameter; each configuration represented a single case. In addition, 25 cases contained no nodules. Images were displayed in three modes: (i) standard, (ii) inverted and (iii) fast-flicking between standard and inverted display modes. Each observer completed the study in a different order of display (i, ii, iii) using a calibrated 5-megapixel monitor. Nodules were localized with mouse clicks and ratings assigned using a 1â10 discrete slider-bar confidence scale. Rjafroc (Pitts- burgh, PA) was used for data analysis; differences in nodule detection performance were considered significant at 0.05.
Results: The observer-averaged weighted jackknife alter- native free-response receiver-operating characteristic figures of merit were 0.715 (standard), 0.684 (inverted) and 0.717 (fast-flicking). Random-reader fixed-case anal- ysis revealed no statistically significant difference be- tween any treatment pair [F(2,8) 5 1.22; p 5 0.345].
Conclusion: No statistically significant difference in nodule detection was found for the three display conditions.
Advances in knowledge: We have investigated the impact of fast-flicking between standard and inverted display modes for the detection of nodules. We found no benefit
Genomic Characterization of Campylobacter jejuni Strain M1
Campylobacter jejuni strain M1 (laboratory designation 99/308) is a rarely documented case of direct transmission of C. jejuni from chicken to a person, resulting in enteritis. We have sequenced the genome of C. jejuni strain M1, and compared this to 12 other C. jejuni sequenced genomes currently publicly available. Compared to these, M1 is closest to strain 81116. Based on the 13 genome sequences, we have identified the C. jejuni pan-genome, as well as the core genome, the auxiliary genes, and genes unique between strains M1 and 81116. The pan-genome contains 2,427 gene families, whilst the core genome comprised 1,295 gene families, or about two-thirds of the gene content of the average of the sequenced C. jejuni genomes. Various comparison and visualization tools were applied to the 13 C. jejuni genome sequences, including a species pan- and core genome plot, a BLAST Matrix and a BLAST Atlas. Trees based on 16S rRNA sequences and on the total gene families in each genome are presented. The findings are discussed in the background of the proven virulence potential of M1
Transcutaneous vagus nerve stimulation (t-VNS): A novel effective treatment for temper outbursts in adults with Prader-Willi Syndrome indicated by results from a non-blind study.
Temper outbursts are a severe problem for people with Prader-Willi Syndrome (PWS). Previous reports indicate that vagus nerve stimulation (VNS) may reduce maladaptive behaviour in neurodevelopmental disorders, including PWS. We systematically investigated the effectiveness of transcutaneous VNS (t-VNS) in PWS. Using a non-blind single case repeat measures modified ABA design, with participants as their own controls, t-VNS was evaluated in five individuals with PWS [three males; age 22-41 (M = 26.8)]. After a baseline phase, participants received four-hours of t-VNS daily for 12 months, followed by one month of daily t-VNS for two-hours. The primary outcome measure was the mean number of behavioural outbursts per day. Secondary outcomes included findings from behavioural questionnaires and both qualitative and goal attainment interviews. Four of the five participants who completed the study exhibited a statistically significant reduction in number and severity of temper outbursts after approximately nine months of daily four-hour t-VNS. Subsequent two-hour daily t-VNS was associated with increased outbursts for all participants, two reaching significance. Questionnaire and interview data supported these findings, the latter indicating potential mechanisms of action. No serious safety issues were reported. t-VNS is an effective, novel and safe intervention for chronic temper outbursts in PWS. We propose these changes are mediated through vagal projections and their effects both centrally and on the functioning of the parasympathetic nervous system. These findings challenge our present biopsychosocial understanding of such behaviours suggesting that there is a single major mechanism that is modifiable using t-VNS. This intervention is potentially generalizable across other clinical groups. Future research should address the lack of a sham condition in this study along with the prevalence of high drop out rates, and the potential effects of different stimulation intensities, frequencies and pulse widths
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Climate Change during and after the Roman Empire: Reconstructing the Past from Scientific and Historical Evidence
Growing scientific evidence from modern climate science is loaded with implications for the environmental history of the Roman Empire and its successor societies. The written and archaeological evidence, although richer than commonly realized, is unevenly distributed over time and space. A first synthesis of what the written records and multiple natural archives (multi-proxy data) indicate about climate change and variability across western Eurasia from c. 100 b.c. to 800 a.d. confirms that the Roman Empire rose during a period of stable and favorable climatic conditions, which deteriorated during the Empire's third-century crisis. A second, briefer period of favorable conditions coincided with the Empire's recovery in the fourth century; regional differences in climate conditions parallel the diverging fates of the eastern and western Empires in subsequent centuries. Climate conditions beyond the Empire's boundaries also played an important role by affecting food production in the Nile valley, and by encouraging two major migrations and invasions of pastoral peoples from Central Asia.Earth and Planetary SciencesHistor
Selective Breeding for a Behavioral Trait Changes Digit Ratio
The ratio of the length of the second digit (index finger) divided by the fourth digit (ring finger) tends to be lower in men than in women. This 2Dâś4D digit ratio is often used as a proxy for prenatal androgen exposure in studies of human health and behavior. For example, 2Dâś4D ratio is lower (i.e. more âmasculinizedâ) in both men and women of greater physical fitness and/or sporting ability. Lab mice have also shown variation in 2Dâś4D as a function of uterine environment, and mouse digit ratios seem also to correlate with behavioral traits, including daily activity levels. Selective breeding for increased rates of voluntary exercise (wheel running) in four lines of mice has caused correlated increases in aerobic exercise capacity, circulating corticosterone level, and predatory aggression. Here, we show that this selection regime has also increased 2Dâś4D. This apparent âfeminizationâ in mice is opposite to the relationship seen between 2Dâś4D and physical fitness in human beings. The present results are difficult to reconcile with the notion that 2Dâś4D is an effective proxy for prenatal androgen exposure; instead, it may more accurately reflect effects of glucocorticoids, or other factors that regulate any of many genes
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Genetic Risk Reclassification for Type 2 Diabetes by Age Below or Above 50 Years Using 40 Type 2 Diabetes Risk Single Nucleotide Polymorphisms
OBJECTIVE: To test if knowledge of type 2 diabetes genetic variants improves disease prediction. RESEARCH DESIGN AND METHODS: We tested 40 single nucleotide polymorphisms (SNPs) associated with diabetes in 3,471 Framingham Offspring Study subjects followed over 34 years using pooled logistic regression models stratified by age (<50 years, diabetes cases = 144; or âĽ50 years, diabetes cases = 302). Models included clinical risk factors and a 40-SNP weighted genetic risk score. RESULTS: In people <50 years of age, the clinical risk factors model C-statistic was 0.908; the 40-SNP score increased it to 0.911 (P = 0.3; net reclassification improvement (NRI): 10.2%, P = 0.001). In people âĽ50 years of age, the C-statistics without and with the score were 0.883 and 0.884 (P = 0.2; NRI: 0.4%). The risk per risk allele was higher in people <50 than âĽ50 years of age (24 vs. 11%; P value for age interaction = 0.02). CONCLUSIONS: Knowledge of common genetic variation appropriately reclassifies younger people for type 2 diabetes risk beyond clinical risk factors but not older people
Ethnicity, voter alignment and political party affiliation - an African case: Zambia
Conventional wisdom holds that ethnicity provides the social cleavage for voting behav-iour and party affiliation in Africa. Because this is usually inferred from aggregate data of national election results, it might prove to be an ecological fallacy. The evidence based on individual data from an opinion survey in Zambia suggests that ethnicity matters for voter alignment and even more so for party affiliation, but it is certainly not the only factor. The analysis also points to a number of qualifications which are partly methodology-related. One is that the degree of ethnic voting can differ from one ethno-political group to the other depending on various degrees of ethnic mobilisation. Another is that if smaller eth-nic groups or subgroups do not identify with one particular party, it is difficult to find a significant statistical correlation between party affiliation and ethnicity - but that does not prove that they do not affiliate along ethnic lines.Wahlverhalten und Mitgliedschaft in politischen Parteien Afrikas ist nur wenig untersucht worden. GewÜhnlich wird argumentiert, dass Ethnizität als soziale Konfliktlinie das Wahlverhalten und die Parteienmitgliedschaft strukturiert. Da dieses Argument auf hoch aggregierten Wahldaten beruht, kann hier ein Ükologischer Fehlschuss vorliegen. Die vorliegende Analyse beruht deshalb auf individuellen Umfragedaten aus Sambia. Das Ergebnis ist, dass Ethnizität tatsächlich eine Rolle fßr das Wahlverhalten und die Parteienmitgliedschaft spielt, aber keineswegs den einzigen Erklärungsfaktor darstellt. Die Analyse offenbart zudem eine Reihe von Einschränkungen und Qualifizierungen, die teilweise methodischer Natur sind. Eine ist, dass ethnisches Wahlverhalten und Parteienmitgliedschaft von einer ethnischen Gruppe zur anderen unterschiedlich ist, dass, wenn sich kleinere ethnische Gruppen oder Untergruppen mit keiner Partei identifizieren, es schwierig wird, statistisch signifikante Korrelationen zu finden - was indessen noch nicht beweist, dass Ethnizität keine Rolle spielt
Radiocarbon re-dating of contact-era Iroquoian history in northeastern North America
A time frame for late Iroquoian prehistory is firmly established on the basis of the presence/absence of European trade goods and other archeological indicators. However, independent dating evidence is lacking. We use 86 radiocarbon measurements to test and (re)define existing chronological understanding. Warminster, often associated with CahiaguĂŠ visited by S. de Champlain in 1615â1616 CE, yields a compatible radiocarbon-based age. However, a well-known late prehistoric site sequence in southern Ontario, Draper-Spang-Mantle, usually dated ~1450â1550, yields much later radiocarbon-based dates of ~1530â1615. The revised time frame dramatically rewrites 16th-century contact-era history in this region. Key processes of violent conflict, community coalescence, and the introduction of European goods all happened much later and more rapidly than previously assumed. Our results suggest the need to reconsider current understandings of contact-era dynamics across northeastern North America
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