Laves Phase in Alloy 718 Fusion Zone

The gas tungsten arc (GTA) welded fusion zone of alloy 718 has been well investigated on the formation of interdendritic Laves phase. This article deals with the various process control methodologies for minimizing the microsegregation and Laves phase such as the enhanced weld cooling rate in GTA welding (GTAW) process and modification in weld metal chemistry. Even though the high energy density welding processes such as electron beam (EB) and laser beam (LB) welding techniques are proven in minimizing the microsegregation and Laves phase, the requirement of conventional GTA welding process still exists in the aerospace industry due to the complex shapes of the components and the inaccessible conditions for executing the welding process. The enhancement in the weld cooling rate and modified weld metal chemistry resulted in the refined fusion zone microstructure and reduced microsegregation. Enhanced weld efficiency on ultimate tensile strength (UTS) and 0.2% YS at 25°C was observed to the tune of 85 to 93% by employing cryogenic cooling in GTA welding process. Similar improvement in weld efficiency at 650°C was observed. However, the evaluated weld efficiencies with cryogenically cooled weld metal were marginally lower than the previous works in EB and LB welds only by 2–3%

A study of diagnostic laproscopy in intra abdominal malignancies

BACKGROUND: Abdominal malignancies are one of the most common malignancy affecting humans Many patients with abdominal malignancies are found at exploration to be unable to undergo resection. Laparoscopy has been suggested as a sensitive method for detecting metastatic disease in this group of patients. Diagnostic laparoscopy effectively establishes a diagnosis, can be therapeutic, and causes less morbidity and mortality than a formal laparotomy. Also there is not much literature about cost effectiveness of the procedure & reduction in convalescence period. OBJECTIVES OF STUDY: 1. Role of diagnostic laparoscopy for staging of abdominal malignancy. 2. To study convalescence period & cost effectiveness of the patient. 3. To assess the ability to avoid unnecessary laparotomies. METHODS: The present study evaluated 30 patients of abdominal malignancies admitted to Stanley Medical College Hospital during the period of January 2013 to December 2013 fulfilling the inclusion and exclusion criteria. Diagnostic Laparoscopy was performed in all 30 patients after taking written consent. Diagnostic Laparoscopy was immediately followed by definitive or palliative surgeries when required. Categorical variables in the study were compared palliative surgeries when required. Categorical variables in the study were compared using Chi square test, contingency coefficient analysis, Independent sample t test, one sample t test using SPSS software. P value of < 0.05 was considered to be significant. RESULTS: Study included total of 30 patients comprising of stomach, biliary & colorectal malignancies with mean age of 53 years (21-70). 13 cases (43.3%) were found to be unresectable on staging laparoscopy and prevented from undergoing unnecessary laparotomy. 6 cases (20%) had liver metastases & 8 cases (26.7%) had peritoneal seedings on staging laparoscopy which were not revealed on preoperative imaging workup. Mean duration of Staging Laparoscopy was 18.83 min (10-30mins). Staging Laparoscopy had minimal major complication rates. Mean convalescence period was 8.2 days for study group & Mean cost for study group was Rs 8,897. It was significantly lower compared to open exploration. INTERPRETATION AND CONCLUSION: A short SL performed just before the planned surgical procedure to certify the operability is found to be safe & very effective. It is very accurate in assessing peritoneal seedings, hepatic metastases which are not found on imaging modalities. Staging laparoscopy has a significant impact on decisions regarding the treatment plan, helps in more careful planning of palliative & resectional procedure in advanced conditions, performing biopsy from sites of dissemination & having histological confirmation. It spares patients from unnecessary laparotomies and has been found to significantly decrease the hospital stay & cost expenditure when compared to open exploration. Staging Laparoscopy should be a routine tool in the armamentarium of all surgeons

(E)-2-[(2-Formyl­phen­oxy)meth­yl]-3-(4-methyl­phen­yl)prop-2-ene­nitrile

In the title compound, C18H15NO2, the dihedral angle between the two benzene rings is 74.8 (1)°. The carbonitrile chain is almost linear, the C—C—N angle being 176.2 (2)°. In the crystal, π–π inter­actions [centroid–centroid distance = 3.842 (1) Å] are observed

Performance Analysis And Experimental Investigation On Exhaust Gas Heat Recovery For IC Engines Using Shell And Tube Heat Exchanger

Increase in energy demand results in shortage of energy. Many effective means were under research to overcome shortage of energy. Recent trend researchers focussing on cogeneration and waste heat recovery in order to improve the efficiency of existing system as well as to avoid energy wastage. In this work waste heat from the exhaust gas is recovered by means of shell and tube heat exchanger to convert cold fluid in to hot fluid. In this system water is used as a working fluid. Water extracts thermal energy to estimate the exhaust heat obtainable from the engine exhaust gases. The exhaust gases which is passed through the tube side of the heat exchanger is obtained from the existing four stroke single cylinder diesel engine whereas water is passed through the shell side of the heat exchanger. The counter flow type heat exchanger arrangement is considered for the analysis. Therefore, the heat transfer characteristics of a system combining compression ignition engine and heat exchanger which recover waste heat from exhaust gas. Performance improvement in this type heat exchanger gives the better USAbility of low grade heat energy.nbs

Molecular Docking Studies for the Assessment of Wound Healing Activity of Phytoconstituents in Heliotropium Indicum

One of the most crucial and complex processes is the skin's multi-stage process of healing after an injury. Heliotropium indicum is a potent antibiotic, anti- inflammatory, anti-neoplastic, anti-oxidant, and wound- healing agent. Heliotropium indicum Linn is the source of the chemical compound in question, which is abundant in sterols, ammines, volatile oils, and the pyrrolizidine alkaloids. Molecular docking studies were conducted on Heliotropium indicum using Argus lab 4.0.1 and Autodock 1.5.7. The proteins PDB ID:1YXO, 3V18, and 4G8R were selected because of their role in wound healing. The pieces work together with the protein responsible for mending wounds. The binding affinities of mupirocin and nitrofurazone are higher than those of the components stigmasterol, eugenol, borneol, and campesterol. In order to better customize Heliotropium indicum to our requirements, we now have a better knowledge of the components of the molecule that interact with their receptors in the wound healing process

Raspberry PI Based Artificial Vision Assisting System for Blind Persons

The main aim of this paper is to implement a system that will help blind person. This system is used by a RASPBERRY PI circuit to provide for the identification of the objects, the first level localization. It also incorporates additional components to provide more refined location and orientation information. The input process is to capture every object around 10m and it is convert into the output processing in voice command which is adopted in Bluetooth headset which is used by blind people using RASPBERRY PI component

SEINE: Methods for Electronic Data Capture and Integrated Data Repository Synthesis with Patient Registry Use Cases

Integrated Data Repositories (IDR) allow clinical research to leverage electronic health records (EHR) and other data sources while Electronic Data Capture (EDC) applications often support manually maintained patient registries. Using i2b2 and REDCap, (IDR and EDC platforms respectively) we have developed methods that integrate IDR and EDC strengths supporting: 1) data delivery from the IDR as ready-to-use registries to exploit the annotation and data collection capabilities unique to EDC applications; 2) integrating EDC managed registries into data repositories allows investigators to use hypothesis generation and cohort discovery methods. This round-trip integration can lower lag between cohort discovery and establishing a registry. Investigators can also periodically augment their registry cohort as the IDR is enriched with additional data elements, data sources, and patients. We describe our open-source automated methods and provide three example registry uses cases for these methods: triple negative breast cancer, vertiginous syndrome, cancer distress

Solar Energy Forecasting: Perspectives of the State-Of-The-Art

Solar energy is a promising renewable energy source, but its intermittent and variable nature poses significant challenges for accurate forecasting. Over the recent years, there has been a remarkable surge in research dedicated to improving the precision of solar energy forecasting models. This review article delves into the state-of-the-art in solar energy forecasting. Beginning with an exploration of the hurdles faced in forecasting solar radiation, we proceed to provide an extensive survey of various forecasting models that have been developed to tackle this complex problem. Factors influencing the accuracy of solar energy forecasts are discussed, and an insight into the future trends in solar energy forecasting is provided. Key areas of focus include machine learning techniques, artificial neural networks (ANNs), and support vector regression

Cloud computing mobile application for remote monitoring of Bell's palsy

Mobile applications provide the healthcare industry with a means of connecting with patients in their own home utilizing their own personal mobile devices such as tablets and phones. This allows therapists to monitor the progress of people under their care from a remote location and all with the added benefit that patients are familiar with their own mobile devices; thereby reducing the time required to train patients with the new technology. There is also the added benefit to the health service that there is no additional cost required to purchase devices for use. The Facial Remote Activity Monitoring Eyewear (FRAME) mobile application and web service framework has been designed to work on the IOS and android platforms, the two most commonly used today. Results: The system utilizes secure cloud based data storage to collect, analyse and store data, this allows for near real time, secure access remotely by therapists to monitor their patients and intervene when required. The underlying framework has been designed to be secure, anonymous and flexible to ensure compliance with the data protection act and the latest General Data Protection Regulation (GDPR); this new standard came into effect in April 2018 and replaces the Data Protection Act in the UK and Europe