Trichosporon beigelli esterase (TBE): a versatile esterase for the resolution of economically important racemates

A hydrolase producing strain Trichosporon beigelli esterase (TBE) isolated from local cottage cheese in its native form has displayed versatility and high efficacy in the kinetic resolution of a wide range of economically important substrates, which include racemic secondary alcohols, such as 1-(6-methoxy-2-naphthyl)ethanol (E � 316), 1-(3,4-methylenedioxyphenyl)ethanol and pentanol(E � 180 and 156 resp.), and alkyl esters of carboxylic acids such as ibuprofen (E � 340), 2-(benzylthio)propanoic acid (E � 1000). In other substrates such as in the primary alcohol 2-(6-methoxy-2-naphthyl)propan-1-ol and carboxylic acids such as 2-(5-bromo-6-methoxy-2-naphthyl)propanoic acid, 2-(2-naphthyloxy)propanoic acid, and substituted 2-thiopropanoic acids, it displayed moderate to low selectivity. Commercial lipases such as CCL, PPL, and PSL were also used in the resolution of the substrates for comparative studies

Abstracts of the International Chemical Engineering Conference 2021: 100 Glorious Years of Chemical Engineering & Technology

This book presents the selected abstracts of the International Chemical Engineering Conference 2021, hosted from the 16th to 19th of September 2021 in virtual mode by the Department of Chemical Engineering, NIT Jalandhar, India. Conference Title: International Chemical Engineering Conference 2021Conference Acronym: ICheEC2021Theme: 100 Glorious Years of Chemical Engineering & TechnologyConference Date: 16-19 September 2021Conference Location: OnlineConference Organizer: Department of Chemical Engineering, NIT Jalandhar, Indi