5 research outputs found
Identification et caractérisation d'un nouveau exchangeur de glutathion qui contribue à la modulation du pH cytosolique et de l'homéostasie redox
PARIS7-Bibliothèque centrale (751132105) / SudocSudocFranceF
HIF-1-dependent regulation of lifespan in Caenorhabditis elegans by the acyl-CoA-binding protein MAA-1
International audienc
A dual role for K63-linked ubiquitin chains in multivesicular body biogenesis and cargo sorting
International audienc
Gex1 is a yeast glutathione exchanger that interferes with pH and redox homeostasis
Gex1 is a glutathione exchanger mostly found at the vacuolar membrane. The expression of Gex1 and Gex2 is induced under conditions of iron depletion, and Gex1 is regulated principally by the iron transcription factor Aft2. Loss of or high Gex1/2 activity modulates PKA and MAPK signaling events