Hyperthermia and Photocatalytic Performance of Magnetic Polyvinyl Alcohol under External Magnetic Field

The promising physical and chemical properties of components of magnetic polymers could enable extending their intelligent behaviors to material applications. Indeed, investigation into magnetic nanofillers to ensure their uniform dispersion within the polymer matrix remains a great challenge at present. In this work, polyvinyl alcohol-stabilized iron oxide nanoparticles (PVA@IONPs) were prepared using ultrasonic-assisted coprecipitation at room temperature. It is possible to produce PVA@IONPs with desirable shapes and sizes, which would enable the control of their hyperthermia and photocatalytic performance under an external magnetic field. The saturation magnetization of PVA@IONPs (45.08 emu g−1) was enhanced to the level of IONPs (41.93 emu g−1). The PVA@IONPs showed good photocatalytic and outstanding self-heating behavior. The hydrogen yield was 60 mmole min−1 g−1 for photocatalyst PVA@IONPs under visible light with magnetic force. In addition, the PVA@IONPs exhibited a higher specific absorption rate (SAR) than IONPs under the same magnetic field conditions. The PVA@IONPs displayed superior self-heating and photocatalytic performances, rendering them appropriate materials for biomedical and environmental applications

Synthesis of Novel Nano-Sulfonamide Metal-Based Corrosion Inhibitor Surfactants

The synthesis of novel corrosion inhibitors and biocide metal complex nanoparticle surfactants was achieved through the reaction of sulfonamide with selenious acid to produce a quaternary ammonium salt. Platinum and cobalt surfactants were then formed by complexing the first products with platinum (II) or cobalt (II) ions. The surface properties of these surfactants were then investigated, and the free energy of form micelles (ΔGomic) and adsorption (ΔGoads) was determined. The obtained cationic compounds were evaluated as corrosion inhibitors for carbon steel dissolution in 1N HCl medium. The results of gravimetric and electrochemical measurements showed that the obtained inhibitors were excellent corrosion inhibitors. The anti-sulfate-reducing bacteria activity known to cause corrosion of oil pipes was obtained by the inhibition zone diameter method for the prepared compounds, which were measured against sulfate-reducing bacteria. FTIR spectra, elemental analysis, H1 NMR spectrum, and 13C labeling were performed to ensure the purity of the prepared compounds

Changes of physicochemical and functional properties of processed cheese made with natural cheddar and mozzarella cheeses during refrigerated storage

Abstract The present study aimed to investigate changes of physicochemical and functional properties of the processed cheeses (PCs) made with Cheddar (PC1), Mozzarella (PC2) and both of them at a ratio of 1:1 (PC3) during storage at 4 °C for 4 months. The results showed that the type of natural cheese used affected the composition of PCs with lower fat content in PC2 due to the lower fat content of Mozzarella cheese used. PC2 with lower fat content showed decreased meltability and oil leakage compared with PC1 and PC3. The stretchability of all the samples significantly (P < 0.05) decreased during storage, and PC1 showed lower stretchability. This was confirmed by increased protein hydrolysis of all the samples during the storage with a higher level of proteolysis in PC1, leading to decreased stretchability of PCs. Further low-field nuclear magnetic resonance analysis indicated more entrapped water in cheese due to moisture migration into the cheese matrix that might squeeze the fat globules to aggregate, causing more fat leakage during later stages of storage. This was evidenced by microstructural analysis showing different extents of increase in fat particle sizes and decrease in free serum in all the PC samples over the storage time. Therefore, the present study provides further understanding of the mechanism of quality change of PC during refrigerated storage as affected by proteolytic properties and composition of natural cheese used

Discovery Potent of Thiazolidinedione Derivatives as Antioxidant, α-Amylase Inhibitor, and Antidiabetic Agent

This work aimed to synthesize safe antihyperglycemic derivatives bearing thiazolidinedione fragment based on spectral data. The DFT theory discussed the frontier molecular orbitals (FMOs), chemical reactivity of compounds, and molecular electrostatic potential (MEP) to explain interaction between thiazolidinediones and the biological receptor. α-amylase is known as the initiator-hydrolysis of the of polysaccharides; therefore, developing α-amylase inhibitors can open the way for a potential diabetes mellitus drug. The molecular docking simulation was performed into the active site of PPAR-γ and α-amylase. We evaluated in vitro α-amylase’s potency and radical scavenging ability. The compound 6 has the highest potency against α-amylase and radical scavenging compared to the reference drug and other members. They have been applied against anti-diabetic and anti-hyperlipidemic activity (in vivo) based on an alloxan-induced diabetic rat model during a 30-day treatment protocol. The most potent anti hyperglycemic members are 6 and 11 with reduction percentage of blood glucose level by 69.55% and 66.95%, respectively; compared with the normal control. Other members exhibited moderate to low anti-diabetic potency. All compounds showed a normal value against the tested biochemical parameters (CH, LDL, and HDL). The ADMET profile showed good oral bioavailability without any observed carcinogenesis effect

Controlled Preparation of Thermally Stable Fe-Poly(dimethylsiloxane) Composite by Magnetic Induction Heating

The most challenging task in the preparation of poly(dimethylsiloxane) composites is to control the curing time as well as to enhance their thermal and swelling behavior. Curing rate can be modified and controlled by a range of iron powder contents to achieve a desired working time, where iron is used as self-heating particles. Iron under alternative current magnetic field (ACMF) is able to generate thermal energy, providing a benefit in accelerating the curing of composites. Three types of iron-Poly(dimethylsiloxane) (Fe-PDMS) composites were prepared under ACMF with iron content 5, 10, and 15 wt %. The curing process was investigated by FTIR, while the morphology and the thermal stability were examined by SEM, DMA, and TGA. The heating&rsquo;s profile was studied as functions of iron content and induction time. It was found that the time required to complete curing was reduced and the curing temperature was controlled by varying the iron content and induction time. In addition, the thermal stability and the swelling behavior of the prepared composites were enhanced in comparison with the conventional PDMS and thus offer a promising route to obtain thermally stable composites

Thiazolidinedione Derivatives: In Silico, In Vitro, In Vivo, Antioxidant and Anti-Diabetic Evaluation

This work aimed to synthesize a new antihyperglycemic thiazolidinedione based on the spectral data. The DFTB3LYP6-311G** level of theory was used to investigate the frontier molecular orbitals (FMOs), chemical reactivity and map the molecular electrostatic potentials (MEPs) to explain how the synthesized compounds interacted with the receptor. The molecular docking simulations into the active sites of PPAR-&gamma; and &alpha;-amylase were performed. The in vitro potency of these compounds via &alpha;-amylase and radical scavenging were evaluated. The data revealed that compounds (4&ndash;6) have higher potency than the reference drugs. The anti-diabetic and anti-hyperlipidemic activities for thiazolidine-2,4-dione have been investigated in vivo using the alloxan-induced diabetic rat model along with the 30 days of treatment protocol. The investigated compounds didn&rsquo;t show obvious reduction of blood glucose during pre-treatments compared to diabetic control, while after 30 days of treatments, the blood glucose level was lower than that of the diabetic control. Compounds (4&ndash;7) were able to regulate hyperlipidemia levels (cholesterol, triglyceride, high-density lipoproteins and low- and very-low-density lipoproteins) to nearly normal value at the 30th day

Experimental and Theoretical Investigations of <i>Argania spinosa</i>’s Extracts on the Antioxidant Activity and Mild Steel Corrosion’s Inhibition in 1 M HCl

The aim of the present research is the evaluation of the extraction process effect on the chemical composition, the antioxidant activities, and the mild steel corrosion inhibition ability of Argania spinosa’s extracts (alimentary oil (AO) and hexanic extract of roasted almonds (HERA)). The chemical composition revealed that both extracts have the same major compounds: Palmitic, linoleic, and stearic acids, with their order slightly different. Electrochemical impedance spectroscopy (EIS), weight loss measurements, and polarization curves were used to estimate AO and HERA’s mild steel corrosion’s inhibition capacity. Based on these three methods, AO registered, respectively, 81%, 87%, and 87% inhibition efficiency while HERA registered 78%, 84%, and 82% inhibition efficiency. The antioxidant activity of AO and HERA was examined in parallel with standard antioxidants (gallic acid and quercetin) using two assays: DPPH* scavenging assay and ferric reducing antioxidant power assay (FRAP). AO had less EC50 in both techniques (DPPH*: 3559.08 ± 161.75 μg/mL; FRAP 1288.58 ± 169.21 μg/mL) than HERA (DPPH*: 3621.43 ± 316.05 μg/mL; FRAP 1655.86 ± 240.18 μg/mL). Quantum chemical and molecular dynamic studies were employed to suggest the adsorption mechanism

Experimental and Theoretical Investigations of Argania spinosa&rsquo;s Extracts on the Antioxidant Activity and Mild Steel Corrosion&rsquo;s Inhibition in 1 M HCl

The aim of the present research is the evaluation of the extraction process effect on the chemical composition, the antioxidant activities, and the mild steel corrosion inhibition ability of Argania spinosa&rsquo;s extracts (alimentary oil (AO) and hexanic extract of roasted almonds (HERA)). The chemical composition revealed that both extracts have the same major compounds: Palmitic, linoleic, and stearic acids, with their order slightly different. Electrochemical impedance spectroscopy (EIS), weight loss measurements, and polarization curves were used to estimate AO and HERA&rsquo;s mild steel corrosion&rsquo;s inhibition capacity. Based on these three methods, AO registered, respectively, 81%, 87%, and 87% inhibition efficiency while HERA registered 78%, 84%, and 82% inhibition efficiency. The antioxidant activity of AO and HERA was examined in parallel with standard antioxidants (gallic acid and quercetin) using two assays: DPPH* scavenging assay and ferric reducing antioxidant power assay (FRAP). AO had less EC50 in both techniques (DPPH*: 3559.08 &plusmn; 161.75 &mu;g/mL; FRAP 1288.58 &plusmn; 169.21 &mu;g/mL) than HERA (DPPH*: 3621.43 &plusmn; 316.05 &mu;g/mL; FRAP 1655.86 &plusmn; 240.18 &mu;g/mL). Quantum chemical and molecular dynamic studies were employed to suggest the adsorption mechanism

Type I&ndash;IV Halogen&#8943;Halogen Interactions: A Comparative Theoretical Study in Halobenzene&#8943;Halobenzene Homodimers

In the current study, unexplored type IV halogen&#8943;halogen interaction was thoroughly elucidated, for the first time, and compared to the well-established types I&ndash;III interactions by means of the second-order M&oslash;ller&ndash;Plesset (MP2) method. For this aim, the halobenzene&#8943;halobenzene homodimers (where halogen = Cl, Br, and I) were designed into four different types, parodying the considered interactions. From the energetic perspective, the preference of scouted homodimers was ascribed to type II interactions (i.e., highest binding energy), whereas the lowest binding energies were discerned in type III interactions. Generally, binding energies of the studied interactions were observed to decline with the decrease in the &sigma;-hole size in the order, C6H5I&#8943;IC6H5 &gt; C6H5Br&#8943;BrC6H5 &gt; C6H5Cl&#8943;ClC6H5 homodimers and the reverse was noticed in the case of type IV interactions. Such peculiar observations were relevant to the ample contributions of negative-belt&#8943;negative-belt interactions within the C6H5Cl&#8943;ClC6H5 homodimer. Further, type IV torsional trans &rarr; cis interconversion of C6H5X&#8943;XC6H5 homodimers was investigated to quantify the &pi;&#8943;&pi; contributions into the total binding energies. Evidently, the energetic features illustrated the amelioration of the considered homodimers (i.e., more negative binding energy) along the prolonged scope of torsional trans &rarr; cis interconversion. In turn, these findings outlined the efficiency of the cis configuration over the trans analog. Generally, symmetry-adapted perturbation theory-based energy decomposition analysis (SAPT-EDA) demonstrated the predominance of all the scouted homodimers by the dispersion forces. The obtained results would be beneficial for the omnipresent studies relevant to the applications of halogen bonds in the fields of materials science and crystal engineering