On the long-run dynamics of income and wealth inequality

We analyse top income and wealth shares data, by conducting a robust estimation of trends, tests for structural breaks, and tests for determining persistence. We include Anglo-Saxon countries, continental Europe and Asian countries, grouped under different percentiles and deciles, spanning a period that is at least close to a century. We find that the top income shares for almost all countries are characterised by broken trends, or level shifts. The preponderance of trend breaks appears in the 1970s and 1980s where after a negative trend changes in magnitude or direction. Finally, shocks to the top income share data are not transitory, which have consequences for policy such as advocating redistributive measures

Biosynthesis of spathulenol and camphor stand as a competitive route to artemisinin production as revealed by a new chemometric convergence approach based on nine locations’ field-grown Artemesia annua L.

Since isopentenyl diphosphate (IPP) and its isomer dimethylallyl diphosphate (DMAPP) are the universal precursors of both essential oil components, and the antimalarial agent artemisinin and its derivatives in Artemesia annua L., this paper aims to correlate the spotted differences in their concentrations by screening Artemesia annua L. field-grown in nine locations around the world that may reveal the role of any these compounds as precursors or competitors in the biosynthetic pathway of the sesquiterpene lactone : artemisinin. Principal component analysis (PCA) revealed that artemisinin is positively correlated to β-pinene, 1.8-cineole, sabinene hydrate, borneol and 1-octen-3-ol; but negatively to artemisinic acid and β-caryophyllene oxide. Hierarchical cluster analysis (HCA) classified locations into two distinct groups in which artemisinin concentration stood as the main driving factor to build similarities between the locations. In parallel, an improved convergence approach based on idiosyncratic similarities able to capture heterogeneity across individuals is proposed, which was able to classify compounds into four distinct clusters. Artemisinin appeared to be cross-linked to p-cymene, cis-carvyle acetate, 4-terpinene-1-ol, β-caryophyllene, β-farnesene, β-selinene, α-selinene, β-caryophyllene oxide and α-costol. It is interesting to see how camphor and spathulenol behaved as a distinct cluster group, which suggests that biosynthesis of these two compounds follows a different but a competitive pathway ; thus limiting their production could be a key to control and enhance the production of artemisinin

“Breakthrough Therapies” for Breast Cancer Metastasis.

Breast Cancer Metastasis (MBC) is an ultimate death sentence remains a challenge for clinicians worldwide.According to the Metastatic Breast Cancer (MBC) Awareness Network about 155,000 patients are living nowadays with MBC, and about 40,000 deaths are reported annually in the United States of America. About 10% of the patients visiting the clinic or appearing at the emergency sittings are diagnosed with stage IV breast cancer at the initial screening and require an urgent and effective treatment, which mainly focuses on controlling the disease and improve the quality of life. A breakthrough in the clinical trials for the treatment of breast cancer metastasis has been observed recently, most of these treatments are mainly drug therapies

Use of Multiplex PCR for Diagnosis of Bacterial Infection Respiratory Mixed

Atypical bacteria grow very slowly in culture or they do not grow at all leading to delays in detection and diagnosis. PCR multiplex was performed on template DNAs extracted from seventy three collected specimens. Thirty seven showed positive indication for the presence of bacterial infection. The incidence of Mycoplasma pneumoniae, Chlamydia pneumonia and Legionella pneumophila as a single infecting agent was 31.5%, 27.5% and 20 % respectively. Dual agent infection caused by Mycoplasma + Chlamydia, Mycoplasma + Legionella and Legionella + Chlamydia was 24%, 20% and 15% respectively. Triple agent infection caused by Legionella + Mycoplasma + Chlamydia was 17.5%. The etiology of the infection was M. pneumoniae, L. pneumophila or C. pneumoniae as a single etiology or in combination of two or three organisms

A Novel Demand Response Management Model to Reduce Smart Grid Costs

DRM means leveling demand curve based on electricity prices. Indeed, using variable price rates, electricity consumers are encouraged to use electricity in periods with cheap electricity price ranges. Therefore, total system cost would decrease efficiently. Motivations: To model dynamics between electricity end-users and utility companies. To present a model with simple implementation on smart households. To reduce electricity production costs and to maximize social welfare.Electrical and Computer Engineering, Department o

Mesure de l'intensité et de la sélectivité du bronzage zooplanctonique diurne et nocturne sur le peuplement physoplanctonique de la retenue Al Massira (Maroc)

La retenue de barrage Al Massira (Maroc) constitue une pièce maîtresse dans le plan d'aménagement du bassin versant de l'Oum Er Rbia. Elle se situe dans la province de Settat, à 120 km au sud-est de Casablanca. La mesure de l'intensité du broutage zooplanctonique sur le peuplement phytoplanctonique a été réalisée à trois périodes différentes; le 20 mars 1992 d'une part et les 27 et 28 mai 1992 d'autre part, avec respectivement des mesures de jour et de nuit . Pour cela, une analyse de l'évolution des densités phytoplanctoniques au sein d'enceintes immergées in situ à 5 et 15 m pendant 8 heures, en absence (enceintes témoins) et en présence (enceintes expérimentales) de zooplancton, a été réalisée. Les résultats obtenus montrent que:- La technique adoptée est performante dans la mesure où les différences entre les densités algales entre les temps initial et final sont en général significatives dans les deux enceintes. - Conformément aux données de la littérature, le broutage apparaît bien comme sélectif; de nombreuses espèces n'apparaissant pas être consommées. - La sélection effectuée par le zooplancton est principalement basée sur la taille des cellules. Toutefois, à tailles égales, certaines espèces phytoplanctoniques semblent être consommées préférentiellement par les copépodes. - Seules les espèces algales présentant un développement important dans les enceintes témoins sont soumises à la prédation.The Al Massira reservoir, located in the district of Settat 120 km south-east of Casablanca, is of great importance notably at the level of the management of the Oum Er Rbia River-catchment basin.Several grazing experiments were performed to assess the intensity of phytoplankton predation by zooplankton species, on 20 March l992, 27 and 28 May 1992, respectively, over the day and the night. Two enclosures were used and incubated in situ at 5 and 15 m over 8 hours, The first enclosure consisted of a mixture of several phytoplankton and zooplankton species. The second was free of zooplancton.The results clearly demonstrated that the technique used in this work seemed to be effective in that a signifïcant difference between the initial and final numbers of phytoplankton species incubated in the enclosure was detected. In addition, we confirmed several literature reports relative to the selective characteristics of herbivore predation on algae: large phytoplankton (e.g., Peridinium cinctum, Ceratium hirundinellaand Staurastrum pingue) were not affected. The grazing pressure depended on the size of preys and on the exudates released by the physiofogically active small phytoplankton species (e.g., Oocystis crassa, Cyclotella sp.) evolving in the enclosures. Among small preys, only species with high growth rate (estimed in the control flask, e.g., Cosmarium sp. and Tetraedron sp.) were subjected to the zooplankton predation. The copepod nightgrazing was lower than that recorder during the day, probably due to a decrease in their ability to detect preys in the dark.Our result contradict several results obtained by the method of NANEY (1971) according to which grazing increases during the night.Two assumptions may be proposed to explain such a discrepancy:- The zooplankton community of the Al Massira Reservoir was quantitatively dominated by the Calanoid Neolovenula alluaudi.Yet, according to HANEY and HALL (1975), these Copepods showed a slight diel grazing change compared to that of Cladocera. It seemed likely that these temporal variabilities were not statistically significant but rather inherent to the overall internal fluctuation oftlte cell metabolism.- The HANEY (1971) method allows estimation of the water volume per unit time, which transits along the digestive tract of zooplankters. Nevertheless, this technique was mostly performed in markedly stratified natural lakes. From a strictly physiological point of view, and as demonstrated by MC LAREN (1963), organisms which evolved in deep layers (low temperature) became metabolically more active when they reached superficial layers (increased temperature). Clearly, this increase in the cell metabolism abilities is translated into a higher volume of water passing through the digestive tract but not necessarily into an increase in ingested phytoplankton preys. Our results went along with the aforementioned interpretation since we clearly demonstrated an optimal Copepoda-grazing selectivity. However, the selection of preys would not imply a direct relationship between the ingested volume of water and energetic inputs

Numerical and Experimental Investigations of Simple 2-D Geometries in Slamming

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