17 research outputs found
Stoffaustausch während der Filmabsorption : Absorption von Ammoniak durch Wasser und Salzsäure
Untersucht wurde die Absorption von Ammoniak aus der Luft durch Wasser und Säure in einem einzelnen Kanal (Rohr mit berieselbaren Wänden) und in einem Turm mit Blechpaketeinsatz. In der Untersuchung wurde der Einfluß der Strömungsgeschwindigkeit, der Gasgeschwindigkeit und der Kanalabmessungen auf den allgemeinen und partiellen Absorptionskoeffizienten bestimmt
Treatment of Patients with Acute Coronary Syndrome with ST Segment Elevation in Clinical Practice of the Republic of Karelia: the Results of 10-year Register
Aim. To study the clinical course, treatment, and outcomes in the patients with ST segment elevation acute coronary syndrome (STeACS) in real clinical practiceMaterial and methods. Our study is based on data of 5694 patients who were sequentially hospitalized in the Regional Vascular Center from 01.01.2009 to 01.01.2019 due to STeACS and included in the Federal Hospital Register. Men prevailed (65.8%); the average age was 68 years old. 14.1% of the patients had the history of myocardial infarction (MI) before this hospitalization. The reperfusion strategy, drug therapy, as well as the risks of complications and outcomes in real clinical practice of the Republic of Karelia were analyzed. Descriptive statistics methods were used to evaluate the results.Results. In the study group a high frequency of reperfusion interventions (83.5%) with a predominance of percutaneous coronary intervention (PCI; 76.2%) was revealed, as well as optimal drug therapy in most patients. Thus, 99.4% of patients took aspirin, 82.8% – clopidogrel, 91.1% – anticoagulants, 91.6% – beta-blockers, 95.6% – statins, 94.2% – angiotensin-converting-enzyme inhibitors/angiotensin II receptors blockers. A risk assessment of hospital and 6-month mortality was performed using GRACE score. The distribution of the hospital risk mortality were the following: 25.7% of patients had a low (49-125 points), 33.7% an average (126-154 points), and 40.6% of patients had a high risk (more than 154 points). At the same time, the risk of 6-month mortality in a half of the patients (51.6%) was low (27-99 points), the average risk (100-127 points) was determined in 23.0% of patients and the high risk (more than 127 points) – in 25.5% of patients. Life threatening complications developed in 38.1% of patients and the most frequent ones were arrhythmias (31.5%). The outcomes at the discharge from the hospital were as follows: 1432 patients (63.5%) had Q MI, 390 (17.3%) – non Q MI, 76 (3.4%) – unstable angina, 21 (0.9%) – MI of unspecified localization and 317 patients (14.1%) – repeated myocardial infarction.Conclusion. According to the results of a 10-year hospital registry of patients with STeACS, a high frequency of reperfusion interventions and an optimal drug therapy in most patients was revealed. However, to increase the effectiveness of treatment, it is necessary to minimize temporary losses both at the prehospital treatment and during reperfusion
CORRELATION OF INFLAMMATION BIOMARKERS WITH THE TRADITIONAL RISK FACTORS IN PATIENTS WITH ACUTE CORONARY SYNDROME
Actuality of cardiovascular diseases today determines the high interest to study pathogenesis of atherosclerosis and to searching new risk factors which could help to optimize primary and secondary prevention. Study the correlation between biomarkers of inflammation and traditional risk factors (TRF) in patients with different forms of ischemic heart disease is really important today.Aim. To determine the correlation between TRF and the level of biomarkers of the inflammation and endothelial dysfunction in patients with acute coronary syndrome (ACS). Material and methods. Patients (n=62) aged from 24 to 50 years (mean age 43.98±4.73), who were admitted to the hospital due to ACS, were included into the study. Correlations between TRF and the levels of biomarkers of the inflammation and endothelial dysfunction were assessed. The following biomarkers levels were determined: high-sensitivity C-reactive protein (hsCRP), homocysteine, soluble vascular cell (sVCAM-1) and intracellular (sICAM-1) adhesion molecule type 1, soluble E-selectin (sE-selectin), nitrate, neopterin, matrix metalloproteinase type 3 (MMP-3).Results. TRF, including modifiable ones, were often revealed in patients of the studied group. Some correlations between TRF and high concentrations of inflammatory biomarkers were determined. Patients with the family history of early cardiovascular diseases had higher concentration of sVCAM-1 (1047.78±516.98 ng/ml) in comparison with the patients without this TRF (705.57±239.28 ng/ml), p=0.017. Patients with arterial hypertension had higher level of MMP-3 (9.31±3.63 ng/ml) versus patients without hypertension (5.02±3.66 ng/ml), р=0.011). Patients with abdominal obesity compared with patients without this TRF demonstrated higher concentration of nitrate in acute (208.45±91.85 ng/ml vs 154.53 ng/ml, р=0.028) and long-term (193.53±40.02 ng/ml vs 173.48 ng/ml, р=0.028) periods of ASC.Conclusion. The study showed the significant correlation between ТRF and high levels of some biomarkers of inflammation and endothelial dysfunctions in patients with ACS. So it is probably associated with more rapid progression of the atherosclerosis, higher risk of atherothrombotic events, complicated course of ischemic heart disease and unfavorable outcomes
Performance of an ambulatory electroencephalogram sleep monitor in patients with psychiatric disorders
On the integration of the methods of forming and research of images of objects against the background of noises and interference
This article discusses the application of complex methods for detecting, recognizing, distinguishing borders and measuring various parameters of noisy, low-contrast, difficult-to-see images of space, air or ground objects. The problem of detecting, recognizing, distinguishing and measuring parameters of objects images (space or air objects, aircraft, ship, ground transport, people, coasts, etc.) is still among the very complex, completely unsolved radio engineering and telecommunications (“connected”) tasks. Currently, infrared (IR) direction finding, optical (laser location) direction finding and radar are used to detect, recognize, distinguish boundaries and measure the parameters of unknown objects against the background of external natural or artificial interference and noise. These methods have their own advantages and disadvantages, which do not always coincide. Therefore, it is of theoretical and practical interest to use them jointly, multifunctionally, or integrationally to identify objects against the background of external natural or deliberate interference and noise. When applying multifunctional methods for detecting, recognizing, distinguishing borders and measuring parameters of noisy, low-contrast images of objects against the background of external natural or artificial interference and noise. Digital processing of objects is mainly used now, which can be defined as a process during which an image is: modified to obtain a new one, which will be more convenient for research by a computer, or by the human eye; it is transformed into a certain set of characteristics and parameters visible and related to the observation area that are automatically analyzed by the computer, or directly presented to a person, taking into account pre-established criteria for developing a final conclusion about the studied object. Typically, the result of digital processing of the received signals is a new image that can be easily converted to analog form and directly observed on a computer display