16 research outputs found
Age and gender identity in a perpetrators of sexual violence against children
The paper devoted to the age and gender identity among the perpetrators of sexual violence against children and discussed the factors lead to pathogenesis of abnormal sexual behavior against children. We have identified particularities of gender and age identity in perpetrators of violent sexual acts against children. It was noted that patients with a diagnosis of pedophilia have abnormalities mostly in cognitive structure of sexual identity, that is shown in undifferentiated age peculiarities of perception of self-image and gender and role stereotypes. These data allow assessing more accurately the abnormalities of sexual sphere, explaining the deviant behavior, as well as structure of age and sex self-identity in persons with the disorder of sexual desire in the form of pedophilia and take a step closer to understanding the mechanisms of abnormal choice of sexual object
INTESTINAL DYSBIOSIS IN CHILDREN WITH FOOD ALLERGY: PATHOGENETIC ASPECTS AND MODERN CORRECTION METHODS
Background paper analyses the role of intestinal micro-flora at the stage of forming immunity, the importance of intestinal microflora abnormalities during the periods of allergic diseases development (primarily food allergies), as well as mechanisms of dysbiosis effect on the allergic processes in child's body. The study discusses the mechanisms of treatment and prevention effect of probiotics for cases of child allergic diseases. The work also specifies modern approaches to correcting dysbiotic abnormalities for children with food allergies, reviews the options of diet and medication treatment of food allergy, suggests a new algorithm of gradual treatment that targets correction of dysbiosis in this patient category.Key words: children, food allergy, dysbiosis, probiotics, prebiotics, diet therapy.</strong
COMBINED SKIN AND RESPIRATORY SYMPTOMS OF ALIMENTARY ALLERGY IN CHILDREN: ETIOLOGY, CLINICS, COMPLEX TREATMENT
The article describes peculiarities of skin and respiratory symptoms of alimentary allergy, main etiological factors and pathogenetical stages of pathology’s formation. Authors present a description of alimentary allergy in different age periods, methods of its diagnostics, treatment of skin and respiratory signs of alimentary allergy.Key words: children, alimentary allergy, atopic dermatitis, respiratory allergy.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(2):74-81
Perception features of the sexual preference object in persons with pedophilia depending on the attitude to sexual desire
The article examines expert and diagnostic aspects of "ego-sintonic / ego-dystonic" types of attitudes to sexual desire and describes importance of studying the basis of desire in the context of sexual offenses against minors. We present results of empirical research which aims to study perception features of the sexual preference object in persons with pedophilia depending on the attitude to sexual desire. The study based on data provided by laboratory of forensic sexology, V.P. Serbsky Federal Medical Research Center of Psychiatry and Addiction, Ministry of Health Care of the Russian Federation. The sample consisted of 30 men with such sexual desire disorder as pedophilia. The results analysis showing differences in the perception of the object of sexual desire according to different attitude to the desire. The results indicate that different types of attitudes to sexual desire correspond to certain characteristics of the perception object. Identified patterns can be used in the creating the criminal prospective portrait, dealing with expert issues, developing correction and preventive programs for patients with a diagnosis of pedophilia
THE ROLE OF COMPOUNDS BASED ON HYDROLYZED PROTEIN IN PROPHYLAXIS AND DIET TREATMENT OF ALIMENTARY ALLERGY IN INFANTS
Alimentary allergy in infants occurs because of intolerance to the cow’s milk protein. Infant formulas with hydrolyzed protein are widely used for the prophylaxis and treatment of alimentary allergy in children. The article describes main peculiarities and principles of administration of hypoallergenic infant formulas and formulas based on hydrolyzates of serum proteins or casein. Special attention is given to the nutrients’ role (nucleotides, long-chain polyunsaturated fatty acids), included into hypoallergenic formulas. The peculiarities and terms of supplementary feeding introduction in patients with alimentary allergy are discussed. Key words: children, alimentary allergy, hypoallergenic formulas, nucleotides, oligosaccharides.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(1):150-156
FOOD ALLERGY PREVENTION IN INFANCY
The article deals with new data about food tolerance induction among the children, belonging to the high risk groups disposed to atopy. Authors show the role of gut microflora in formation of child immune system, effect of breast feeding on activation of local immune response, growth stimulation of bifid bacteria and lactic acid bacilli. The present work gives the randomized research findings, which confirm the effectiveness of prolonged breast feeding, use of highly or partially hydrolyzed mixtures and timely introduction of supplemental feeding in food allergy prevention.Key words: prevention, food allergy, children, breast feeding, hypo allergic mixtures, milk protein hydrolysates, supplemental feeding, gut microflora, probiotics
VITAMIN AND MINERAL SUBSTANCE PROVISION FOR THE CHILDREN, SUFFERING FROM THE ALLERGIES IN MODERN CONDITIONS
(Педиатрическая фармакология. – 2008;5(3):76-81
VITAMIN AND MINERAL SUBSTANCE PROVISION FOR THE CHILDREN, SUFFERING FROM THE ALLERGIES IN MODERN CONDITIONS
(Педиатрическая фармакология. – 2008;5(3):76-81
Gastrointestinal manifestations of cow's milk protein allergy in children
Recent years have seen an increase in the prevalence of food allergies globally, and pathological conditions associated with impaired tolerance to certain food are posing bigger problem for pediatrics. Food allergy is currently believed to be an adverse (pathological) reaction caused by intake of food, conditioned by certain immune mechanisms, including IgE-mediated and non-IgE-mediated allergic reactions
Pharmacotherapy in pregnant women
E.A. Sandakova1, I.G. Zhukovskaya2, M.V. Semenova2, A.F. Vaganova3, A.V. Kuznetsova1, T.E. Kazymova1, O.A. Belousova2, L.P. Makarova2
1Academician E.A. Vagner Perm State Medical University, Perm, Russian Federation
2Izhevsk State Medical Academy, Izhevsk, Russian Federation
3F.Kh. Gral City Clinical Hospital No. 2, Perm, Russian Federation
Aim: to analyze the prescription of medications in pregnant women based on outpatient charts of women’s clinics.
Patients and Methods: retrospective cohort study was conducted in three women’s clinics of Perm and two women’s clinics of Izhevsk. Data on the prescription of medications in 361 pregnant and postpartum women during pregnancy (2017–2018) were obtained by copying individual medical charts. Additionally, we compared our findings with the results of the Russian Pharmacoepidemiologic Study (2007).
Results: pharmacotherapy was prescribed in 100% of women. On average, 12.6 medications were prescribed during gestation. Most medications were prescribed in the second trimester (on average, 5.5 medications). In the first and third trimesters, 2.4 and 4.7 medications were prescribed, respectively. The most prescribed drugs were vitamins and minerals (70.4%), feminine hygiene products (37.1%), progestogens (33.1%), herbal urinary antiseptics (29.8%), and systemic antibiotics (14.2%). Pharmacotherapy defects included medications inconsistent with diagnosis (48.6%), a combination of several drugs with similar pharmacological effects (16.5%), and polypharmacy defined as the use of five or more medications (25.8%). A two-fold reduction in drug aggression as well as an increase in the dotation of vitamin-mineral complexes compared to 2007 were reported.
Conclusions: our findings illustrate positive trends for treating pregnant women in the last 9–10 years and increased safety of treatment (the lack of drugs with potential teratogenic or embryotoxic effects) but also indicate the need in the permanent audit and adjustment of prescriptions based on clinical guidelines. Pre-pregnancy preparation is a perspective way to reduce the intensity of drug therapy during pregnancy. As a result, drug burden shifts to a pre-gestational period. Pre-pregnancy preparation provides favorable conditions for developing an embryo and fetus.
Keywords: pharmacotherapy, pregnancy, polypharmacy, micronutrients, vaginal hygiene, progestogens, urinary antiseptics.
For citation: Sandakova E.A., Zhukovskaya I.G., Semenova M.V. et al. Pharmacotherapy in pregnant women. Russian Journal of Woman and Child Health. 2021;4(2):115–118. DOI: 10.32364/2618-8430-2021-4-2-115-118.
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