29 research outputs found
Improving Newborn Survival in Low-Income Countries: Community-Based Approaches and Lessons from South Asia
David Osrin and colleagues discuss the critical importance of reducing global neonatal mortality in developing countries and how community-based approaches can help
Business networks and localization effects for new Swedish technology-based firmsâ innovation performance
This study examines the business networks and localization effects for new technology-based firms (NTBFs) in the context of innovation performance (the number of patents and product differentiation). In this regard, the study includes 28 variables. A survey was conducted in 2016 with 401 Swedish NTBFs that were small and young (the employment mean was 1.80 and the average age of each firm was 28.3\ua0months). The biggest category of NTBFs was knowledge-intensive high-technology services, followed by medium high-technology manufacturing, and high-technology manufacturing. Hypotheses on how business networks and localization are related to innovation performance were tested using principal component analysis, correlation analysis, and regression analysis. The results show that the primary significant factor for innovation performance regarding business networks and localization dimensions are professional network services, while industrial and regional areas also have a positive relationship on product differentiation. Our study also shows that innovation performance enhances firmsâ abilities to access external financing through professional network services (e.g., venture capital companies)
Federalism and Investor Protection: Constitutional Restraints on Preemption of State Remedies for Securities Fraud
'Cave canem!': cuidado com os 'Pronapianos'! Em busca dos jovens da arqueologia brasileira
Low-Order Equivalent System Identification for the Tu-144LL Supersonic Transport Aircraft
Retrospective and Recent Examples of Aircraft Parameter Identification at NASA Dryden Flight Research Center
Internal Auditing in Mid-Nineteenth Century Railroad Companies: Comparing the Practices of American and British Railroads
Exploring marginalization and exclusion in renewable energy development in Africa:a perspective from western individualism and African ubuntu philosophy
The objectives of this chapter are to understand the ethical principles that are relevant to the achievement of energy justice; to explore energy marginalization in Africa and to analyse this marginalization from the perspectives of Western and Ubuntu ethics; to underscore the violation of ethics in renewable energy deployment; and to find means of addressing energy injustice through proper application of the respective ethical principles. Part of the data for the study were sourced from the reports of the Renewable Energy for Twenty-First Century (REN21)
Molecular Basis for Telomere Repeat Divergence in Budding Yeast
Telomerase is a ribonucleoprotein enzyme that adds repetitive sequences to the ends of linear chromosomes, thereby counteracting nucleotide loss due to incomplete replication. A short region of the telomerase RNA subunit serves as template for nucleotide addition onto the telomere 3âČ end. Although Saccharomyces cerevisiae contains only one telomerase RNA gene, telomere repeat sequences are degenerate in this organism. Based on a detailed analysis of the telomere sequences specified by wild-type and mutant RNA templates in vivo, we show that the divergence of telomere repeats is due to abortive reverse transcription in the 3âČ and 5âČ regions of the template and due to the alignment of telomeres in multiple registers within the RNA template. Through the interpretation of wild-type telomere sequences, we identify nucleotides in the template that are not accessible for base pairing during substrate annealing. Rather, these positions become available as templates for reverse transcription only after alignment with adjacent nucleotides has occurred, indicating that a conformational change takes place upon substrate binding. We also infer that the central part of the template region is reverse transcribed processively. The inaccessibility of certain template positions for alignment and the processive polymerization of the central template portion may serve to reduce the possible repeat diversification and enhance the incorporation of binding sites for Rap1p, the telomere binding protein of budding yeast