Primary Ovarian Ectopic Pregnancy: A Case Report

Introduction: Ectopic pregnancy is a serious health problem that leads to maternal mortality and morbidity. The current article was based on the record of a female patient with primary ovarian ectopic pregnancy. Case Presentation: The patient was a 28-year-old female with regular previous menstrual cycle and without using any contraception method. She presented with right lower abdominal pain and amenorrhea. Transvaginal sonography findings revealed a gestational sac in the right ovary. Finally, primary ovarian ectopic pregnancy was diagnosed by laparotomy and confirmed by histopathology. Conclusions: To prevent misdiagnosis, an awareness of this issue should be developed by gynecologists, surgeons, and radiologists. Keywords: Ovary, Ectopic Pregnanc

Effect of low-glycemic load diet on changes in cardiovascular risk factors in poorly controlled diabetic patients

Background: One dietary strategy aimed at improving both diabetes control and control of cardiovascular risk factors is the use of low glycemic index diets. These diets have been reported to be beneficial in controlling diabetes, and also increase high density lipoprotein cholesterol (HDL-C), lower serum triglyceride, and reduce glycated protein. Aim: Therefore, we aimed to investigate the effect of a low glycemic index-low glycemic load (GL = 67-77) diet on lipids and blood glucose of poorly controlled diabetic patients. Materials and Methods: In an intervention study, 100 poorly controlled diabetic patients (age 52.8 ± 4.5 years) who were taking insulin or on oral medication underwent administration of low GL diet (GL = 67-77; energy = 1800-2200 kcal, total fat = 36%, fat derived from olive oil and nuts 15%, carbohydrate = 41%, protein = 22%) for 10 weeks. Patients were recommended to follow their regular lifestyle. Total cholesterol, low density lipoprotein (LDL), HDL, triglyceride, glycated hemoglobin (HbA1c), weight, and body mass index (BMI) were measured before and 10 weeks after the intervention. Results: Before intervention, initial blood cholesterol and triglyceride concentrations were 205.9 ± 21.6 and 181.5 ± 22.2, respectively, and were reduced to 182.6 ± 18.2 and 161.6 ± 16.7, respectively, after 10 weeks intervention (P < 0.001). LDL reduced and HDL increased significantly. The HbA1c percentage reduced by 12% (from 8.85 ± 0.22% to 7.81 ± 0.27%) (P < 0.001), and also their weight significantly reduced from 74.0 ± 5 kg to 70.7 ± 4.6 kg (P < 0.001). Conclusion: This study demonstrated that low GL diet having lower carbohydrate amount and higher fat content is an appropriate strategy in blood lipid and glucose response control of poorly controlled diabetic patients

پروفایل سرشت های عاطفی به عنوان یک عامل زمینه ساز برای پسوریازیس پلاک مزمن

مقدمه: اگرچه رابطه نزدیکی بین پسوریازیس و مسائل روانی از جمله سرشت عاطفی وجود دارد، اما مطالعات کمی به این ارتباط پرداخته اند. این مطالعه با هدف بررسی پروفایل سرشت عاطفی در بیماران مبتلا به پسوریازیس پلاکی مزمن انجام شد.روش‌ کار: این مطالعه مقطعی در سال 98-1397 در کلینیک سرپایی پوست بیمارستان امام رضا (ع) مشهد انجام شد. در مطالعه حاضر، 40 بیمار پسوریازیس و 40 داوطلب سالم همسان از نظر جنس و سن شرکت کردند. ابزارهای تحقیق شامل پرسشنامه  ممفیس، پیزا، پاریس و سن دیگو  (TEMPS-A)، پرسشنامه اضطراب بک (BAI) و پرسشنامه افسردگی بک II (BDI-II)  بود. برای مقایسه متغیرهای اسمی و طبقه‌ای از آزمون‌های تی، من-ویتنی و مجذور خی استفاده شد. برای ارزیابی همبستگی ها از آزمون های اسپیرمن و پیرسون استفاده شد.یافته‌ها: در مجموع، 36 نفر از 80 بیمار (45%) مرد بودند. خلق و خوی افسرده، سیکلوتایمیک و مضطرب در گروه پسوریازیس به طور معنی‌داری برجسته‌تر بود (001/0 P<)، در حالی که نمره هیپرتایمیک در گروه شاهد به‌طور قابل‌توجهی بالاتر بود (023/0=P). بین شدت بیماری (نمره PASI) و سرشت عاطفی مختلف ارتباط معنی داری وجود نداشت. مدت درگیری پسوریازیس با تمام سرشت های عاطفی همبستگی منفی متوسطی داشت (05/0 P<) به جز سرشت هیپرتایمیک. شیوع اضطراب (80 درصد در مقابل 30 درصد، 40=n؛ 001/0 P<) و افسردگی (60 درصد در مقابل 5/32 درصد، 40=n؛ 009/0= P) در بیماران پسوریازیس به طور معنی‌داری بیشتر از گروه شاهد بود.نتیجه گیری: به نظر می رسد سرشت سیکلوتایمیک، افسرده و مضطرب و همچنین اضطراب و افسردگی در بیماران پسوریازیس به طور قابل توجهی شیوع بیشتری داشته باشد. با این حال، این ها با شدت بیماری همبستگی نداشتند

Posterior reversible encephalopathy syndrome in SARS‐CoV‐2 infection: A case report and review of literature

Abstract Consider PRES in SARS‐CoV‐2 infected patients who develop encephalopathy, seizures or impaired vision; especially if the disease is complicated by respiratory distress and need for mechanical ventilation

Factors Associated With Neurological Manifestations in Patients With COVID-19

Background: The coronavirus disease 2019 (COVID-19) is the most terrible pandemic of a respiratory disease that we had in the past century. Most existing studies explore different manifestations in COVID-19. Few recent studies have described neurological manifestations of patients with COVID-19 but their associations with age, laboratory findings, and mortality rates have not been explored well. Methods: This case-control study includes 263 patients with COVID-19 without neurological symptoms (control group) and all patients with COVID-19 with the central nervous system symptoms (n=460, case group) hospitalized between February 2020 and April 2020. Data on demographic factors, medical history, symptoms, and laboratory tests, all are extracted from medical records. Results: Out of 723 patients with confirmed SARS-CoV-2 infection, 460 (63.6%) were identified to have at least one neurological manifestation. The mean ages of patients with and without neurological manifestation were 60.6±18.0 and 60.8±15.7 years, respectively. The most common symptoms were myalgia (41%), headache (20.3%), and loss of consciousness (LOC) (16.5%). Women were more likely to develop a neurological manifestation (P = 0.001). Moreover, smoking history was significantly more in patients with neurological manifestations (P=0.03). Also, we compared two groups in terms of tracheal intubation. The need for tracheal intubation was 19% and 12% in patients with and without neurological manifestations, respectively. Furthermore, the prevalence of intensive care unit (ICU) admission was 28% and 24% in patients with COVID-19, with and without neurological manifestations, respectively. Some of the neurological manifestations such as LOC, limbs weakness, and seizure might need more ICU admission and tracheal intubation. The frequency of comorbidities and the laboratory test results were almost similar between the two groups. Conclusion: Myalgia, headache, and LOC were the most common neurological manifestations and their distributions varied depending on age. Only a few neurological manifestations were related to mortality and morbidity rates, while some of them occurred in mild cases