166 research outputs found

    Reliability Assessment of Power Distribution Networks Considering Covid-19 Pandemic

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    Dynamic Analysis of Rotor Speed and Electrical Torque of Brushless Doubly Fed Induction Generator (BDFIG) Under Symmetrical and Unsymmetrical Faults

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    The brushless doubly fed induction generator (BDFIG) has the potential to be employed as a variable speed wind turbine generator. Owing to brushless configuration of this generator, its reliability is higher than DFIG. Most of the grid faults are unsymmetrical. Hence, this paper analyzes dynamic behavior of BDFIG under symmetrical and unsymmetrical faults and presents dynamic models for both fault types. In order to validate the results of analysis, simulations have been carried out using MATLAB/Simulink software. Then, the control winding (CW) current is compared under symmetrical and unsymmetrical faults

    Effect of selegiline on the hippocampal ischemia-reperfusion injuries and cognitive impairments following global ischemia in male rats

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    Introduction: Selegiline, a selective monoamine oxidase type B inhibitor, has been shown to have neurotrophic and anti-apoptotic properties and to protect neurons in experimental models of cerebral ischemia. The aim of this study was to investigate whether selegiline could enhance cognitive and functional recovery in stroke disease. Selegiline is a drug that has demonstrated antioxidant and neuroprotective effects, as documented in the permanent middle cerebral artery occlusion model in rats. Widely used in the treatment of Parkinson's disease and in recent studies showed anti-inflammatory and anti-apoptotic properties. It has been shown to reduce total brain damage after transient hypoxia– Ischemia. Methods and Results: The male rats were randomized into four groups: Control groups, Control + Selegiline (2 mg/kg), stroke induction groups and stroke+ Selegiline (2 mg/kg). Selegiline was gavaged after 4 days from beginning of the investigation. In this regard, we tested whether 1) Administration of selegiline is able to inhibit abnormality behaviors related to global ischemia in Male Rats 2) Behavioral changes are associated with mitochondrial dysfunction in the hippocampus and 3) Administration of selegiline is able to alter immune-inflammatory factors in the hippocampus. Therefore, using valid and qualified behavioral tests for the assessment of stroke like behaviors such as novel object recognition test (NOR) were used for confirmation of stroke induction in rats. Then, animals were sacrificed and hippocampi were dissected out and stored at -80 °C. The samples were divided into two different groups; first set of samples were used for preparation of tissue homogenate, on which measurement of oxidative stress parameters and nitrite levels were performed. The second set of samples were fixed in 10% formalin, sectioned, and stained with hematoxylin and eosin (H&E) for pathological evaluations. The statistical analysis showed a significant improvement in most neuropsychological tests after two weeks in the study group. Conclusions: Data on experimental models of cerebral ischemia have suggested a marked activation of the nigrostriatal dopaminergic system by selegiline that might contribute to the protection against ischemia-induced neurodegeneration

    Comparison of physical and hydrodynamic properties of two Iranian commercial pomegranates

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    The aim of this study was to determine and compare several physical and hydrodynamic properties of two commercial pomegranate cultivars in Iran (Poost sefid and Malas-Yazd).  Values of geometric diameter (74.61-82.45 mm), volume (176-503 mm3), true density (970.25-1,028.30 kg/m3) and packing coefficient (0.48-0.55) showed statistically significant difference at the 1% level.  Besides, projected area and face surface area of cv. Poost sefid were 15 and 18 percent more than cv. Malas-Yazd, respectively (P0.05), respectively.  Further, buoyancy force levels of cv. Poost sefid (3.25 N) and cv. Malas-Yazd (2.41 N) had statistically significant difference at the level 5%.  The rupture force values of Iranian pomegranate varieties had significant differences at Y and Z-axes loading (

    Evaluation of medical error status in various wards of Shohadaye Ashayer Hospital, Khorramabad, Iran

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    Abstract: Medical errors are known as the most important challenges that healthcare systems in all countries are encountered to them. To provide security and safety for patient is one of the major items in the health care systems. Confessing medical errors imposed on patient and education system is found to be an important aspect of medical ethics and care in turn lowers incidence of errors. Given the importance of identifying and reporting occurred medical errors, the present research aimed to assess medical errors in hospital wards of Shohadaye Ashayer Hospital Khorramabad so that findings of this research can inspire us to incorporate medical errors as a very important subject in the curriculum of medical students and finally physicians can do best examination and treatment with minimal or no errors and inaccuracies. The present research is descriptive in nature which lasted from April to March 2015. Statistical population (subjects) included employees and supervisors, nurses, staffs, lab safety facilitator, pharmacy safety facilitator, surgery room personnel, equipment and personnel in the hospital wards, including the emergency department, men surgery, women surgery, operating room, orthopedics, internal medicine ward, neurology, laboratory room, surgery, infectious, ophthalmic, reception, pharmacy and CCU hospital in Shohadaye Ashayer Hospital- Khorramabad. © 2009-2016, JGPT

    Beta-amyloid exhibits antagonistic effects on alpha 7 nicotinic acetylcholine receptors in orchestrated manner

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    AbstractAlthough beta-amyloid (Aβ) has been regarded as the principal toxic factor in the pathogenesis of Alzheimer’s disease (AD), it plays important physiological roles in phenomena such as neuron survival, synaptic plasticity, and memory formation. There are numerous plausible reasons to assume that all of the mentioned pathological and physiological functions of Aβ may be partially mediated via alpha 7 nicotinic acetylcholine receptor (nAChR). Agonistic and antagonistic aspects of Aβ on nAChRs may explain this paradox in peptide–receptor function. It seems that Aβ shows antagonistic effects on α7 nAChR in a dose-dependent manner, and its pathologic function may partially correlate with antagonization of the receptor.If this hypothesis is supported, the related mechanisms of neurotoxicity, neuroprotection, memory formation, and AD pathogenesis might be identified. In addition, such knowledge helps make a more valid interpretation of neuron signaling and a better design of AD animal models. In addition, it may provide new insights into AD therapy development via reducing the amount of Aβ and inhibiting peptide aggregation

    Predictors of In-hospital Mortality after Primary Percutaneous Coronary Intervention for ST-segment Elevation Myocardial Infarction

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    Introduction: Treatment of myocardial infarction (MI) has been successfully developed, especially after introducing primary percutaneous coronary intervention (PPCI) as it nowadays is the recommended treatment for ST-segment elevation myocardial infarction (STEMI). Objective: This study aimed to evaluate the in-hospital mortality of STEMI patients treated with PPCI according to gender and other likely risk factors. Methods: This cross-sectional study presents a part of the results of a single-center registry in Imam Ali cardiovascular center affiliated to Kermanshah University of medical science (KUMS). From June 2016 to December 2017, 731 consecutive patients undergoing PPCI registered. Data were collected using a case report form developed by European Observational Registry Program (EORP). The relationship between in-hospital mortality and predicting variables was assessed using the Chi-square test, t-test, and univariate and multivariate logistic regression models (Forward LR). Results: Totally, 155 patients (approximately 21%) were female. The mean age of women and men was 65.2 and 57.5, respectively (p=0.001). There were differences between women and men in hypertension (58.1% vs. 30.4%, respectively, p=0.001), diabetes mellitus (26.5% vs. 14.9%; p=0.001), hypercholesterolemia (37.4% vs. 18.6%; p=0.001), and history of prior congestive heart failure (5.2% vs. 2.0%; p=0.016). Although more men were current smokers (58.7% (men) vs. 15.5% (women); p=0.001). Women had a significantly greater incidence of multi-vessel disease, thrombolysis in myocardial infarction (TIMI) flow grade of 0/1 before PPCI, and longer symptom-to-balloon time. In-hospital mortality was higher in women than in men (5.2% vs. 1.9%; p=0.024). Multivariate analysis identified age ≥ 60 years, Killip class≥ II, and post-procedural TIMI flow grade < 3, but not female sex, as independent predictors of in-hospital mortality. Conclusion: In-hospital mortality after PPCI in women was higher than men, though this difference was likely due to the severe clinical profile in women. Also, female gender was not identified as an independent predictor of death

    Sex Differences in Risk Factors Profile and Angiographic Pattern of the Patients Undergoing Coronary Angiography

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    Introduction: Coronary artery disease (CAD) is a costly problem and its presentations and risk factors may differ by sex. Objective: This study aimed to evaluate the risk factors profile and angiographic pattern of the patients undergoing coronary angiography, according to their gender. Methods: This cross-sectional study was conducted on 741 patients who were referred for coronary angiography from March to August 2018 at Imam Ali cardiovascular center, western Iran. Using a checklist, we collected the demographic, clinical, biochemical, and lab parameters and angiographic findings in these patients. Also, differences between groups were compared using Chi-square and independent t-tests. Results: Women were different from men in terms of the prevalence of hypertension (71.7% vs. 45.3%), diabetes mellitus (34.9% vs. 17.8%), and hypercholesterolemia (26.4% vs. 17.1%). Whereas, men were more likely to be smoker (28.7% vs. 0%) and obese (42.09±16.68 vs. 29.12±4.72). Total Cholesterol and Triglycerides were higher in women compared to men, which were statistically significant. Glucose plasma was significantly higher in women compared to men (p=0.01).  Both atherogenic (low-density lipoprotein (LDL)) and protective (high-density lipoprotein (HDL)) cholesterol were higher in women than men. Women were more likely to take antiplatelet (i.e. Aspirin) and antihypertensive therapies (i.e. beta-Blocker, angiotensin receptor blockers (ARBs), and angiotensin converting enzyme (ACE) inhibitors) than men. Also, it was shown that, Men were more likely to have two-vessel disease (p=0.041) and three-vessel disease (P=0.013) compared to women. Disease in the right coronary artery (RCA) (28.9% vs. 14.4%), circumflex (LCx) (26.0% vs. 15.3%), and left anterior descending (LAD) (37.8% vs. 26.4%) was more plausible to occur in men compared to women (p≤0.05). Conclusion: Access and use of health care programs are needed to control CAD risk factors. The findings of the current study showed the significance of gender in the extent of coronary artery blockages

    Financial Performance Model of Sports Product Manufacturers Based on Entrepreneurial Marketing and Market Orientation with the Mediating Role of Information Technology

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    Today, the sports industry is known through modern technology, especially in the field of manufacturing sports tools and equipment. The present study uses correlation and applied methodology, which was done in the field using Structural Equations Modeling (SEM). The statistical population included producers of sports products, of which 320 producers from Iran were considered through available sampling. Morris (2002) Standard Entrepreneurial Marketing Questionnaire, Moghimi Market Orientation (2011), Noh and Fitzsimmons Information Technology (1999), and Azizi (2011) Financial Performance Questionnaire were used to collect data. Finally, 292 questionnaires were received physically and electronically. The results showed that entrepreneurial marketing and market orientation had a direct and indirect effect (mediated by technology) on financial performance and they significantly affected the financial performance. Finally, the model had the goodness of fit. In general, manufacturers who adopted a combination of entrepreneurial marketing strategy and information technology had better and more rational financial performance by taking advantage of attractive entrepreneurial opportunities. According to the research results, it is suggested that manufacturers provide the consumers with superior value by paying attention to the market orientation and innovation, to enable the company to achieve a competitive advantage

    Sex Differences in Risk Factors Profile and Angiographic Pattern of the Patients Undergoing Coronary Angiography

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    Introduction: Coronary artery disease (CAD) is a costly problem and its presentations and risk factors may differ by sex. Objective: This study aimed to evaluate the risk factors profile and angiographic pattern of the patients undergoing coronary angiography, according to their gender. Methods: This cross-sectional study was conducted on 741 patients who were referred for coronary angiography from March to August 2018 at Imam Ali cardiovascular center, western Iran. Using a checklist, we collected the demographic, clinical, biochemical, and lab parameters and angiographic findings in these patients. Also, differences between groups were compared using Chi-square and independent t-tests. Results: Women were different from men in terms of the prevalence of hypertension (71.7% vs. 45.3%), diabetes mellitus (34.9% vs. 17.8%), and hypercholesterolemia (26.4% vs. 17.1%). Whereas, men were more likely to be smoker (28.7% vs. 0%) and obese (42.09±16.68 vs. 29.12±4.72). Total Cholesterol and Triglycerides were higher in women compared to men, which were statistically significant. Glucose plasma was significantly higher in women compared to men (p=0.01).  Both atherogenic (low-density lipoprotein (LDL)) and protective (high-density lipoprotein (HDL)) cholesterol were higher in women than men. Women were more likely to take antiplatelet (i.e. Aspirin) and antihypertensive therapies (i.e. beta-Blocker, angiotensin receptor blockers (ARBs), and angiotensin converting enzyme (ACE) inhibitors) than men. Also, it was shown that, Men were more likely to have two-vessel disease (p=0.041) and three-vessel disease (P=0.013) compared to women. Disease in the right coronary artery (RCA) (28.9% vs. 14.4%), circumflex (LCx) (26.0% vs. 15.3%), and left anterior descending (LAD) (37.8% vs. 26.4%) was more plausible to occur in men compared to women (p≤0.05). Conclusion: Access and use of health care programs are needed to control CAD risk factors. The findings of the current study showed the significance of gender in the extent of coronary artery blockages
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