Evaluation of Results of Conservative Therapy in Patients with Transient Osteoporosis of Hip

   The aim of this study to evaluate general characteristics of 18 cases with transient osteoporosis of the hip(TOH) in our hospital within 3-year and to present their follow-up results after conservative treatment. Physical examination and laboratory findings, hip graphs and magnetic resonance imaging(MRI), Harris hip scores(HHSs), and treatment and follow-up results of cases were retrospectively evaluated. The mean duration of complaints of 6 females and 12 males was 6.1±2.7 weeks before the treatment. Only hyperbaric oxygen (HBO) therapy and a pair of Canadian crutches, but no medical therapy, were recommended for three female patients since they were on breastfeeding. As a standard management, other patients were protected from weight-bearing with Canadian crutches and underwent medical therapy with diclofenac sodium, acetylsalicylic acid, risedronate sodium and an additional HBO therapy. HHS increased from 55.6±7.8 to 88.8±5.8 on the 3rd month and to 96.0±1.8 on the 6th month after the treatment. Change in score with time was found significant.

Does the Difference in Leukocyte Concentration of PRP Affect the Short-Term Follow-Up Results in Cases Diagnosed with Early Stage Knee Osteoarthritis?

This prospective study was conducted for the clinical evaluation of pain severity and knee functionality following PRP injections with different leukocyte (WBC) concentrations applied to cases diagnosed with knee osteoarthritis. A total of 109 patients were included in the study. According to the leukocyte content the PRP injections were prepared as low-leukocyte content PRP (P-PRP) and high concentration leukocyte content PRP (L-PRP). Patients were divided into 2 groups. Group 1 (n=44) received low-leukocyte content PRP and Group II (n = 65) received high-leukocyte content PRP. The patients were evaluated clinically with Visual Analog Scale (VAS) and Knee Society Score (KSS). The changes in the PLT levels of the L-PRP group after the procedure compared to the levels prior to the procedure were found to be statistically significantly greater than the changes in the PPRP group. The mean VAS score of all the cases before treatment was 9.05±0.91 and this score decreased to 3.71±1.46 within 12 months. The increases in the mean Knee Society Score (KSS) values were determined as 16.92±1.97 within 6 months and 16.89±2.97 within 12 months in the P-PRP group and 19.71±1.24 within 6 months and 19.86±0.42 within 12 months in the L-PRP group. The most important aspect of this study is that, in contrast to many other studies, the results continued after the 6th month and were reported to be good in the 12th month. It was also recorded that L-PRP was clinically superior to P-PRP in the treatment of early stage knee osteoarthritis