15 research outputs found

    Alcohol-Related Violence among the Australian Aboriginal and Torres Strait Islanders of the Northern Territory: Prioritizing an Agenda for Prevention-Narrative Review Article.

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    Alcohol - related violence among Australian Aboriginal and Torres Strait Islanders (also called as "Indigenous") is a major public health concern in Northern Territory of Australia. There is dearth of epidemiological data that link three contributing epidemics: alcohol misuse, violence, and trauma in the Northern Territory. In this review, we aimed to concentrate on how these epidemics intersect among the Indigenous people in the Northern Territory. In our descriptive review, we have searched published papers, publicly available government and health department reports web sites reporting relevant data on these three risk factors in the Northern Territory. The high rate of family and domestic violence and assaults in the Australian Territory indicates an increased correlation with high risk alcohol use compared to unintentional injuries. Heavy drinking pattern and harmful use of alcohol among Indigenous people are more likely to be associated with the incidence of violent assaults and physical injuries in the Northern Territory. We are trying to emphasize our understanding of co-occurring risk factors on the alcohol - violence relationship and urging a need for interventional approaches to reduce the public health issues in the Northern Territory

    Metastatic prostate cancer mimicking primary osteosarcoma of the jaw: an infrequent clinical case.

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    Prostate cancer metastasizing to the mandible is a rare occurrence. This case describes a patient whose presenting symptom was a painless swelling of the left mandible. Radiological investigation demonstrated a lesion within the left mandibular ramus, and subsequent biopsy confirmed the diagnosis of metastatic prostate cancer

    The risk factors of head and neck cancer and their general patterns in Australia: a descriptive review and update.

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    The purpose of this article is to provide a descriptive review of risk factors of head and neck cancer (HNC), with particular interest in their general patterns in Australia. All these risk factors are deeply perplexing, with socioeconomic, cultural, and geographic variables. We reviewed articles from PubMed, MEDLINE, and Google Scholar by using keywords such as risk factors, alcohol, tobacco, human papilloma virus (HPV), environmental risk factors, and other risk factors. We selected relevant articles after they completely fit into the inclusion criteria for this review. Previous reports highlight that smoking tobacco, consuming alcohol, and HPV infection are the major risk factors for HNC. Geographical variations in incidence rates are indicative of differences in the prevalence of risk factors among countries. HNC could be prevented by reducing the prevalence of established risk factors

    Predictability of Recurrence using Immunohistochemistry to delineate Surgical Margins in mucosal Head and Neck Squamous Cell Carcinoma (PRISM-HNSCC): study protocol for a prospective, observational and bilateral study in Australia and India.

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    Treatment failure and poor 5-year survival in mucosal head and neck squamous cell carcinoma (HNSCC) has remained unchanged for decades mainly due to advanced stage of presentation and high rates of recurrence. Incomplete surgical removal of the tumour, attributed to lack of reliable methods to delineate the surgical margins, is a major cause of disease recurrence. The predictability of recurrence using immunohistochemistry (IHC) to delineate surgical margins (PRISM) in mucosal HNSCC study aims to redefine margin status by identifying the true extent of the tumour at the molecular level by performing IHC with molecular markers, eukaryotic initiation factor, eIF4Eand tumour suppressor gene, p53, on the surgical margins and test the use of Lugol's iodine and fluorescence visualisation prior to the wide local excision. This article describes the study protocol at its pre - results stage. PRISM-HNSCC is a bilateral observational research being conducted in Darwin, Australia and Vellore, India. Individuals diagnosed with HNSCC will undergo the routine wide local excision of the tumour followed by histopathological assessment. Tumours with clear surgical margins that satisfy the exclusion criteria will be selected for further staining of the margins with eIF4E and p53 antibodies. Results of IHC staining will be correlated with recurrences in an attempt to predict the risk of disease recurrence. Patients in Darwin will undergo intraoperative staining of the lesion with Lugol's iodine and fluorescence visualisation to delineate the excision margins while patients in Vellore will not undertake these tests. The outcomes will be analysed. The PRISM-HNSCC study was approved by the institutional ethics committees in Darwin (Human Research Ethics Committee 13-2036) and Vellore (Institutional Review Board Min. no. 8967). Outcomes will be disseminated through publications in academic journals and presentations at educational meetings and conferences. It will be presented as dissertation at the Charles Darwin University. We will communicate the study results to both participating sites. Participating sites will communicate results with patients who have indicated an interest in knowing the results. Australian New Zealand Clinical Trials Registry (ACTRN12616000715471)

    Образы материнства в современной женской поэзии: ретрансляция архаических представлений и новые культурные традиции

    No full text
    The purpose of this article is to provide a descriptive review of risk factors of head and neck cancer (HNC), with particular interest in their general patterns in Australia. All these risk factors are deeply perplexing, with socioeconomic, cultural, and geographic variables. We reviewed articles from PubMed, MEDLINE, and Google Scholar by using keywords such as risk factors, alcohol, tobacco, human papilloma virus (HPV), environmental risk factors, and other risk factors. We selected relevant articles after they completely fit into the inclusion criteria for this review. Previous reports highlight that smoking tobacco, consuming alcohol, and HPV infection are the major risk factors for HNC. Geographical variations in incidence rates are indicative of differences in the prevalence of risk factors among countries. HNC could be prevented by reducing the prevalence of established risk factors
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