Factors Associated with Revision Surgery after Internal Fixation of Hip Fractures

Background: Femoral neck fractures are associated with high rates of revision surgery after management with internal fixation. Using data from the Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) trial evaluating methods of internal fixation in patients with femoral neck fractures, we investigated associations between baseline and surgical factors and the need for revision surgery to promote healing, relieve pain, treat infection or improve function over 24 months postsurgery. Additionally, we investigated factors associated with (1) hardware removal and (2) implant exchange from cancellous screws (CS) or sliding hip screw (SHS) to total hip arthroplasty, hemiarthroplasty, or another internal fixation device. Methods: We identified 15 potential factors a priori that may be associated with revision surgery, 7 with hardware removal, and 14 with implant exchange. We used multivariable Cox proportional hazards analyses in our investigation. Results: Factors associated with increased risk of revision surgery included: female sex, [hazard ratio (HR) 1.79, 95% confidence interval (CI) 1.25-2.50; P = 0.001], higher body mass index (fo

Etizolam: Use and safety profile in children and adolescent

Introduction: Etizolam is a benzodiazepine that has anxiolytic, anticonvulsant, hypnotic, sedative, amnesic, and muscle-relaxant properties. It is used in adults with anxiety, depressive, somatization symptoms, generalized anxiety disorder, and panic disorder. Aims: The aim of the study was to chart review the use and safety of Etizolam in children and adolescents. Settings and Design: This study was a retrospective chart review. Methods: Patients who are on Etizolam and had at least 2 weeks follow-up were included for the study. The indications, effectiveness, and adverse effects were noted. Statistical analysis used: Data was analysed using Epi Info 7. Descriptive statistics were used. Results: 57 (38.51%) patients had been treated with Etizolam. The mean age of children was 13.59 years (7-18 years). Amongst the patients prescribed Etizolam, 37 (64.91%) had a data of follow-up of at least 2 weeks. 25 (67.57%) patients had moderate to complete improvement, 5 (13.51%) had mild improvement and 7 (18.92%) had no improvement. The adverse events were noted only in 3 (8.11%) patients. Conclusions: Etizolam is effective in treating common psychiatric symptoms and disorders in children and adolescents and is well tolerated with minimal adverse effects

Multisource keyword extraction and graph construction for privacy preservation

Privacy preservation is an important branch of Data Mining which handles hiding of an individual's sensitive data without affecting the data usability. This paper proposes a new technique to provide privacy preservation of sensitive data based on the semantic context. Multisource Keyword Extraction and Graph Construction for Privacy Preservation involves extracting keywords from various data formats and preserving privacy among the keywords extracted using the techniques of Vector Marking. Initially, data cleaning and preprocessing is done on the document to extract keywords by applying techniques such as parsing, duplicate elimination, stemming and indexing. The document can be either PDF, SQL or Word files. After preprocessing, a context graph is generated from the keywords extracted with the help of context dictionaries such as WordNet and DBpedia. This context graph acts as a primary source of reference for all user queries. Privacy preservation of sensitive information is achieved using various Vector Marking techniques. The data input by the user can be classified as structured, unstructured and semi-structured data. Appropriate Vector Marking approaches are used for the given input data format. The keyword specified by the user in the input data as private is queried in the context graph to obtain the correlated words and these words are hidden from the access of the other users. Thus solving some of the issues related to privacy leakage. © 2017 ACM