The Effectiveness of Jung’s Self-Knowledge on the Adaptability and Marital Satisfaction of Mothers with Hearing-Impaired Children

Background and Aim: Hearing-impairment and hearing loss are humans’ most common neurological and sensory injuries. Having a child with hearing loss, in addition to affecting the amount of stress on the family and parents, can also affect the marital satisfaction of the couple. This study aimed to evaluate the effectiveness of Jung’s self-knowledge on the adaptability and marital satisfaction of mothers with hearing-impaired children. Methods: This research was quasi-experimental with a pretest-post-test design with a control group. The study’s statistical population includes all mothers with hearing-impaired children living in Yazd City, Iran. A total of 30 women were selected using the purposive sampling method and were randomly divided into the control (15 people) and intervention groups (15 people). The intervention group received Jung’s self-knowledge training in eight 90-minute sessions once a week, while the control group received no training. Data were collected through a marital satisfaction questionnaire and a family adaptation questionnaire. The data were analyzed at the level of descriptive and inferential statistics. Results: The results of the data analysis showed a significant difference between the variables of compatibility and marital satisfaction in the post-test of the experimental and control groups. Conclusion: Jung’s self-knowledge affects the adaptability and marital satisfaction of mothers with hearing-impaired children. Therefore, self-knowledge with Jung’s method can be useful for improving the adaptability and marital satisfaction of mothers with hearing-impaired children

CuO-NiO Nano composites: Synthesis, Characterization, and Cytotoxicity ‎evaluation ‎

Objective(s): In this work, CuO- NiO nano-composites were synthesized via free-surfactant co-precipitation method and then their physiochemical properties, as well as cytotoxicity and antifungal effects, were studied. Methods: The structural and optical properties of CuO-NiO nanostructures were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM), Atomic force microscope (AFM), UV–Vis absorption, and vibrating sample magnetometer (VSM) techniques. MTT assay was used to evaluate the cytotoxicity of nanostructures. Results: The cubical structure of CuO- NiO nano-composites was confirmed by the XRD technique. The optical study of the samples by UV-Vis indicted a blue shift in absorption wavelength with decreasing particle size due to quantum size effect. The super magnetic behavior of CuO-NiO nano composites after calcination was confirmed by magnetic characterization instrument. Finally, the results of cytotoxicity evaluation of CuO-NiO nano-composites at the lower concentrations on Breast cancer MDA cell lines demonstrate no significant toxicity. Minimum inhibitory concentration range and Minimum fungicidal concentration of nanoparticle were determined 0.97-15.62, 7.81µg/ml and for fluconazole were 1.75-25 µg/ml and 12.58 µg/ml, respectively. Conclusions: The study result of antimicrobialof CuO-NiO nano composites indicated an MIC90 antifungal activity with a concentration of 3.90µg/ml against vaginal isolates of C. albicans. The results of cytotoxicity study of nano-composites at concentration of 50µg/ml and 10µg/ml on the cell line of Breast cancer MDA was equivalent to %60 and %80, respectively

Efficacy of hyoscine butylbromide and promethazine on the labor\'s active phase duration: a systematic review and meta-analysis of randomized controlled trials

Background & Aims:  There are different types of drugs to shorten prolonged labor. Spasmolytic drugs are used frequently in the delivery section to overcome cervical spasms and reduce the duration of labor. The study's objective was to evaluate the therapeutic efficacy of hyoscine N-butyl bromide (HBB) and Promethazine on the duration of the active phase of labor. Materials & Methods: We searched the Science Direct, PubMed Scopus, Google Scholar, MEDLINE, Web of Science, Cochrane Library, PsycINFO, and ProQuest databases, and reviewed the literature and reference lists of retrieved articles. We included reports of quantitative studies published in all Persian and English articles from 2000 to 2021 that focused on Promethazine or Hyoscine during. Two authors independently screened titles and abstracts and assessed articles in full text against the inclusion criteria. These criteria included vertex presentation, no previous uterine surgery, intact membranes, and spontaneous labor, with mothers having no contraindications for normal vaginal delivery.    Results:  Out of a total of 170 records initially screened, we included 44 articles in our review, and other studies were excluded. The results showed that 10, 20, 40 mg of HBB decreased the first stage of labor duration by 147.02 min, 58.95 min, and 71.60 min, respectively. Additionally, HBB decreased the first stage of labor duration by 100.61 min in multiparous women and 66.04 min in primipara women. To evaluate the Promethazine effect on labor duration, the results showed that the combined MD was not significant (p=0.67, 0.85, and 0.44 in the first, second, and third stages, respectively). Conclusion:  HBB is more effective in multiparous women compared to primiparous women. On the other hand, Promethazine has no effect on reducing total labor duration and any stages of labor, so its use is not recommended