4-Bromo­methyl-6-meth­oxy-2H-chromen-2-one

The structure of the title coumarin derivative, C11H9BrO3, is stabilized by weak inter­molecular C—H⋯O hydrogen bonds

4-Bromo­methyl-7,8-dimethyl­coumarin

In the title mol­ecule, C12H11BrO2, all non-H atoms with the exception of the Br atom are essentially coplanar (r.m.s. deviation = 0.018 Å). The C—Br bond is inclined by 80.17 (12)° to this plane. The crystal structure is stabilized by weak C—H⋯O hydrogen bonds

Comparative analysis of serum titanium level in patient with healthy dental implant and patients with peri-implantitis- A cross sectional prospective study

Objectives: Titanium dental implants can last for more than two decades in the oral environment. Corrosion of the implant surface can release metallic particles or ions into surrounding tissue. The metallic constituents like titanium in human blood serum have not been fully studied. The study compares titanium serum levels before and after dental implant placement and compares levels in patients with healthy implants and those with per-implantitis. Methods: The study comprised 2groups of Group 1 patient observing implant surgery and group 2 patients with diagnosed peri-implantitis. Each group comprised of 60 patients. Serum titanium level was measured from blood obtained from Group 1 at three different intervals (one month prior to implant surgery, 4th and 8th month after successful loading) and from Group 2 during the course of peri-implantitis by inductively coupled plasma–mass spectroscopy. The statistical analysis was done for the obtained data. Results: Analysis showed a raised level of serum titanium at 4th month of post implant placement (2.39 mg/dl) and in patient with peri-implantitis(2.94 mg/dl) and both levels are significantly differ (ANOVA test) from pre-surgical estimation of serum titanium level (1.79 mg/dl). Conclusions: Understanding the correlation between titanium corrosion and peri-implantitis is vital for enhancing the long-term success and safety of dental implants. Additional research is required to investigate these links and potential strategies to protect the well-being of implant patients

2-(5-Methyl-1-benzofuran-3-yl)acetic acid

The asymmetric unit of the title compound, C11H10O3, contains two crystallographically independent molecules, A and B, with closely matching conformations (r.m.s. overlay fit = 0.105 Å). In each case, the OH group of the acetic acid residue occupies a position approximately antiperiplanar to the C atom of the heterocycle. A short intramolecular C—H...O contact occurs within each molecule. In the crystal, carboxylic acid A+B dimers generate R22(8) loops

6-Chloro-4-(4-methylphenoxymethyl)-2H-chromen-2-one

In the title compound, C17H13ClO3, the coumarin and phenoxy moieties are essentially co-planar, making a dihedral angle of 1.99 (7)°. The phenoxy moiety is oriented antiperiplanar with respect to the coumarin ring as indicated by the C—C—O—C angle of −179.97 (16)°. In the crystal, the sheet-like packing is stabilized by intermolecular C—H...O and C—H...Cl hydrogen bonds

Crystal structure of 7,8-benzocoumarin-4-acetic acid

The fused-ring system in the title compound [systematic name: 2-(2-oxo-2H-benzo[h]chromen-4-yl)acetic acid], C15H10O4, is almost planar (r.m.s. deviation = 0.031 Å) and the Car—C—C=O (ar = aromatic) torsion angle for the side chain is −134.4 (3)°. In the crystal, molecules are linked by O—H...O hydrogen bonds, generating [100] C(8) chains, where the acceptor atom is the exocyclic O atom of the fused-ring system. The packing is consolidated by a very weak C—H...O hydrogen bond to the same acceptor atom. Together, these interactions lead to undulating (001) layers in the crystal