8-Hydroxyisoquinolines

Petaline, an alkaloid from Leontice leontopetalum, Linn, has been shown by synthetic and degradative experiments to be a 2,2-dimethyl-8-hydroxy-7-methoxy-1-(p-methoxybenzyl)-1,2,3,4-tetrahydroisoquinolinium salt and is the first benzyl-isoquinoline alkaloid reported with this oxygenation pattern