The First Case of Adult-Onset Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Adenitis Syndrome with Splenomegaly in Iran

Background: Periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome (PFAPA) is an auto-immune based disease known as a syndrome for pediatrics which typically occurs in children ≤ 5 years of age, but in 2008, for the first time, one adult case of this disease was reported. Case Presentation: Our case, a 19 year-old young man who is the first adult-onset PFAPA patient in Iran and was accompanied by splenomegaly. Since March 2017, the patient suffered from periodic febrile attacks (39-40 °C). During these fever attacks, the patient had many aphthous ulcers in his mouth, swollen glands in his neck and sore in the back of the throat. The patient was admitted to a hospital in Tehran during a severe fever attack due to weakness, lethargy, high-temperature and slight abdominal pain in the left upper quadrant (LUQ) area. Abdominal sonography was done and spleen size was larger than normal and was determined to be 32×140 mm (splenomegaly). All data were collected from a reliable governmental laboratory in Tehran. Conclusion: Following the rejection of the causes of other diseases, according to the patient's symptoms, the diagnosis of adult-onset PFAPA was given to the patient and the patient was cured with one dose of long-acting Betamethasone ampoule 1ml intravenous at the onset of fever attacks. The disease has remitted after injection of this medicine at the onset of each attack rapidly after about 2-3 hours. Also, Montelukast has been given to the patient and we saw his febrile attack intervals increased. &#160

A new complication after receiving the MRNA12-73 (Moderna) vaccine for Coronavirus disease (COVID-19) in Iran: A case report

Introduction: The recent pandemic of the SARS-CoV-2 virus has significantly increased the mortality and disability burden in many people worldwide. Several effective vaccines have been introduced since the outbreak of the coronavirus. These vaccines work through several different immunization pathways to create effective immunity. In this respect, there have been no reports of patients with symptoms of lumbar radiculopathy and puffiness of the hands after receiving corona vaccines. This article presents a clinical case report of these symptoms after receiving the MRNA12-73 (Moderna) vaccine. Overall, finding effective, low-complication, and safe solutions against this virus can have a beneficial effect in reducing the side effects of the Corona vaccine and maintaining the health and lives of people. Case history: A 73-year-old male patient developed lumbar radiculopathy and puffy hands after receiving the corona (COVID-19) vaccine. He was infected with COVID-19 about 60 days after receiving the MRNA12-73 (Moderna) vaccine. Conclusion: Attention to the occurrence of any side effects after injecting corona vaccines requires additional studies

A new complication after receiving the MRNA12-73 (Moderna) vaccine for Coronavirus disease (COVID-19) in Iran: A case report

Introduction: The recent pandemic of the SARS-CoV-2 virus has significantly increased the mortality and disability burden in many people worldwide. Several effective vaccines have been introduced since the outbreak of the coronavirus. These vaccines work through several different immunization pathways to create effective immunity. In this respect, there have been no reports of patients with symptoms of lumbar radiculopathy and puffiness of the hands after receiving corona vaccines. This article presents a clinical case report of these symptoms after receiving the MRNA12-73 (Moderna) vaccine. Overall, finding effective, low-complication, and safe solutions against this virus can have a beneficial effect in reducing the side effects of the Corona vaccine and maintaining the health and lives of people. Case history: A 73-year-old male patient developed lumbar radiculopathy and puffy hands after receiving the corona (COVID-19) vaccine. He was infected with COVID-19 about 60 days after receiving the MRNA12-73 (Moderna) vaccine. Conclusion: Attention to the occurrence of any side effects after injecting corona vaccines requires additional studies. It is also important to follow up on any clinical signs of suspected coronary involvement, even after the vaccination.&nbsp

A Comparative Study on Effective Factors in Patient Safety Culture from the Nursing Staff Points of View

Introduction: Patient safety and its requirements fulfillment are today one of the useful valuation indicators in healthcare organizations. Thus, patient safety culture and its promotion are referred to as one of the most important issues raised in the country. The present study aims to examine the effective factors (personal and organizational) in patient safety culture from the point of view of nursing staff in Bahman and Parsian private hospitals. Method: The study has an analytical cross-sectional design and is an applied research. HSOPSC (with Cronbach’s alpha coefficient was 0.82) and researcher-devised questionnaires (with Cronbach’s Alpha equal to 0.912) were the only data collection tools. Statistical population includes nursing staff of Bahman and Parsian private hospitals in north-west Tehran. A sample consisting of 150 nurse shift supervisors and head nurses was selected from the population. Necessary data for completing questionnaires were collected by interview. Data were analyzed using SPSS16 software. Given the levels of measurement for the variables, valid measures of central tendency (mean, standard deviation), correlation tests, Chi-square, t- test, and ANOVA were used. Results: The findings showed us that such factors as organizational commitment, error reporting system, management support, reward system, and employee empowerment equipment distribution have important roles in patient safety. Their P-values are reported <0.001 for all of them. Patient safety was not significantly associated with age (P=0.964), educational level (P=0.154), and work experience (P=0.888) There is no low awareness about safety culture in any hospital and their mean awareness about patient safety culture was equal to 3.13 ±0.478 and 3.68 ±0.587 in Parsian and Bahman hospitals, respectively (P<0.001). Conclusion: Error reporting system and organizational commitment respectively have the most and the least effect on promoting patient safety culture. Empowerment heightens the awareness of employees, enhances their performance and productivity, reduces errors caused by lack of awareness, and improves patient safety. Reward system and organizational commitment had the least effect