A systematic review and meta-analysis of mobile phone messaging intervention on vaccine preventable diseases

The re-emerging of vaccine preventable diseases is a global public health burgeoning issue. The incompleteness of vaccination or low uptake rate is due to low awareness of the importance of vaccines, forgetfulness, poor counselling, and health education from the healthcare providers. Mobile phone messaging reminder was one of the most studied interventions to overcome these problems in the last decade due to increasing usage of mobile phones in daily living activities. Therefore the aim of this study was to analyse the effectiveness of mobile phone messaging intervention on vaccination programmes of preventable diseases worldwide. Methods. A systematic literature search of randomised controlled trials on Cochrane database that were published for the past 10 years was done; in which 10 articles were selected for critical appraisal and qualitative synthesis. Out of the 10 articles, 9 articles were selected and proceeded with meta-analysis based on GRADE risk of bias assessment. Results. The overall vaccination coverage of mobile phone messaging in the intervention group was higher than the control group [61,586 (47.7%) versus 61,571(45.7%)] with significant pooled vaccination prevalence difference (PD) of 0.02 (CI 0.01, 0.03). In the subgroup analysis, the pooled PD of childhood vaccination coverage was not significant although significant pooled PD of 0.03 (CI 0.01, 0.04) was detected in the influenza vaccination coverage. Conclusion. This review and meta-analysis have strengthened the evidence that mobile phone messaging is an effective intervention method to increase vaccination coverage, especially for influenza vaccination. However, its effect on childhood vaccination coverage was inconclusive and needed more high quality research

Safety of dengue vaccine (CYD-TDV) in Asia: A systematic review

Application Dengue fever vaccine (CYD-TDV) in Asia currently remains quite limited and controversial due to safety issues not yet adequately evaluated. Therefore, the purpose of our review was to assess the safety of the CYD-TDV vaccine based on an analysis of data on its effectiveness in Asia. A search for relevant keywords in electronic databases found 309 scientific articles, of which only four publications were included in the review. The baseline serotype prevalence among study participants was 50-80%. With regard to the safety of the CYD-TDV vaccine, it was shown that reactions at the injection site (pain, edema, erythema) were noted with a relative risk (RR) of 95% CI (0.46-1.76), and systemic reactions (fever, headache, myalgia) were also RR 95% CI (0.89-1.81). Of the four papers included in the review, three contain data on a number of severe adverse effects at RR 95% CI (0.92-2.11). With regard to immunity, it was shown that for DENV-2 there was a high geometric mean titer of 67.8 (95% CI 64.8-70.8), DENV-3 - in 73.1 (95% CI 69.9-76.3), and for DENV-4 - in 65 ( 95% CI 62-67.9), when even lower values ​​are found, this is consistent with other published work on the immunogenicity of the CYD-TDV vaccine against DENV serotypes. Our review shows that the CYD-TDV vaccine may be considered for use in Asia, but subject to a number of conditions and following these safety guidelines. 3), and for DENV-4 - in 65 (95% CI 62-67.9), when, when even smaller values ​​are found, this is consistent with other published works on the immunogenicity of the CYD-TDV vaccine against DENV serotypes. Our review shows that the CYD-TDV vaccine may be considered for use in Asia, but subject to a number of conditions and following these safety guidelines. 3), and for DENV-4 - in 65 (95% CI 62-67.9), when, when even smaller values ​​are found, this is consistent with other published works on the immunogenicity of the CYD-TDV vaccine against DENV serotypes. Our review shows that the CYD-TDV vaccine may be considered for use in Asia, but subject to a number of conditions and following these safety guidelines

Knowledge, attitude and practice on COVID-19 among students during the early phase of pandemic in a university in Borneo, Malaysia

Background: COVID-19 related knowledge, attitude and practice plays a major role in determining the readiness of the community to adopt the behavioural change towards recommended preventive measures outlined by public health officials. This study aims to assess the knowledge, attitude, and practice regarding COVID-19 among university students as well as its associated factors. Method: This is a cross sectional study that was conducted among students in a public university during the early phase of COVID-19 pandemic in Malaysia. An online validated self-administered questionnaire was used to collect the data. Mann-Whitney U and Kruskal Wallis test was used to determine the association between independent variables with knowledge, attitude, and practice score.Results: Overall response rate of this study was 92.9 (n=524). Median score of knowledge domain was 78.0 (IQR= ±12.0), median attitude score of 49.0 (IQR= ±5.0), and median practice score of 80.0 (IQR= ±11.0). The mean knowledge, attitude and practice score were significantly higher among diploma holder (vs degree holder, p<0.05), residing in main Kota Kinabalu campus (vs non-KK campus, p<0.001), studying in medical faculty (vs non-medical faculty, p<0.001), and attended COVID-19 education (vs non-attendance; p<0.05).Conclusion: COVID-19 related knowledge and attitude were below satisfactory level during earlier phase of the pandemic. However, majority of respondents have positive behaviour towards COVID-19 prevention. This highlights the importance of accurate and tailored health education to improve the level of knowledge, attitude and practice of recommended measures to prevent COVID-19 spread

Factors of food premises not attaining "A" grading in Sabah, Malaysia Borneo

Introduction: Up to 70% of the food-water related illness is related to food services hygiene and safety standard. An important and crucial enforcement operation conducted by this division is the inspection of premises and food sampling. This is of paramount importance as food premise grading is directly related to consumers’ health and safety which is in line with the third United Nations Sustainable Developmental Goal of good health and wellbeing. Aim: This study aims to identify the components and factors that are commonly related with food premises that do not obtain an “A” grading. Methodology: A cross-sectional study was conducted in 2017 among 315 food premises in Kota Kinabalu, Sabah that were under the jurisdiction of The Kota Kinabalu City Hall. Data from the food premise inspection forms were reviewed and analysed via multivariate analysis. Results: Premises that were non-compliant with health checks on all food handlers (OR 36.72, 95% CI 10.00-135.44), poor condition of the toilets (OR 6.96, 95% CL 2.35-20.63), ineffective fly control (OR 10.35, 95% CI 1.91-56.02), no availability of garbage cans (OR 3.01, 95% CI 1.01-9.01) and no separate storage for food items and chemical (OR 3.11, 95% 1.06-9.07) were significantly associated with not obtaining “A” grading. Conclusion: More focus and attention need to be paid to these factors not only for premises to attain “A” grading but also to improve the safety and hygiene of food that is consumed by the public

Impact of social distancing on covid-19 and other related infectious disease transmission: A systematic review

Similar to other coronaviruses, COVID-19 is transmitted mainly by droplets and is highly transmissible through close proximity or physical contact with an infected person. Countries across the globe have implemented public health control measures to prevent onward transmission and reduce burden on health care settings. Social or physical distancing was found to be one of appropriate measure based on previous experience with epidemic and pandemic contagious diseases. AIM: This study aims to review the latest evidence of the impact of social or physical distancing implemented during COVID-19 pandemic toward COVID-19 and other related infectious disease transmission. The study uses PRISMA review protocol and formulation of research question was based on PICO. The selected databases include Ovid MEDLINE and Scopus. Thorough identification, screening and eligibility process were done, revealed selected 8 articles. The articles then ranked in quality through Mixed Method Appraisal Tool. A total of eight papers included in this analysis. Five studies (USA, Canada, South Korea and the United Kingdom) showed physical distancing had resulted in a reduction in Covid-19 transmission. In comparison, three other studies (Australia, South Korea and Finland) showed a similar decline on other infectious diseases (Human Immunodeficiency Virus, other sexually transmitted infections, influenza, respiratory syncytial virus, and Vaccine-Preventive Disease. The degree of the distancing policy implemented differs between strict and lenient, with both result in effectiveness in reducing transmission of infectious disease. Physical or social distancing may come in the form of extreme or lenient measure in effectively containing contagious disease such as COVID-19, however the stricter the measure will give more proportionate impact toward the economy, education, mental health issues, morbidity and mortality of non-COVID-19 diseases. Since we need this measure to ensure the reduction of infectious diseases transmission to help flattening the curve which allow much needed time for healthcare system to prepare adequately to response, “Precision physical distancing” can be implemented which will have more benefit toward the survival of the community as a whole

Colorectal cancer and potential predictors of never screened for faecal occult blood test: A narrative review

Colorectal cancer (CRC) is a major public health threat. Therefore, CRC screening uptake has been a focus with the established precancerous lesion and the strong association of early detection with staging and survival of the disease. However, CRC screening is relatively low in many countries. This article briefly discussed the current situation of CRC, recommendations, and current uptake of CRC screening in various countries. Besides that, this article also highlights the potential factors that help to predict the CRC screening uptake worldwide. Identification of those factors could guide policymakers to develop an effective strategy to improve the CRC screening uptake and ultimately improve the health outcome of the population

Prevalence of abnormal urinary cadmium and risk of albuminuria as a primary bioindicator for kidney problems among a healthy population

The prevalence of chronic kidney disease is increasing globally, ranking 27th as the cause of death in the 1990s, rising to 18th in 2010 and 10th in 2019. Non-communicable diseases such as diabetes and hypertension have been identified as the common contributing factors, while there is also evidence linking environmental pollutants, especially cadmium, to kidney disease. This study aimed at investigating the level of urinary cadmium and its relationship to albuminuria as an early indicator of kidney problems in the Kepong community. Respondents were surveyed as part of several health-related programs organized by the Kepong District Health Office involving local communities in and around the district from April 2019 to December 2019. Urinalysis of two urine samples was carried out using a Mission reagent strip and an Inductively Coupled Plasma Mass Spectrometry (ICP-MS) test to detect the presence and level of urinary cadmium. A total of 240 respondents were enrolled from April 2019 to December 2019. Urinalysis of two urine samples was carried out using a Mission reagent strip and an Inductively Coupled Plasma Mass Spectrometry (ICP-MS) test to detect the level of urinary cadmium. The respondents’ average age was 41-year-old (±13.23). Among them, 49.6% were male, 85.0% Malay, 5.8% Chinese and 8.3% Indian. 55.0% had background of tertiary, 39.6% secondary and 5.4% primary level of education. 52.1% were categorized in B40, 34.6% in M40 and 13.3% in T20 based on monthly household income category. 26.7% were hypertensive, 6.7% diabetic, 4.2% had dyslipidemia, 51.7% had urinary cadmium above the alert level, and 27.1% had albuminuria. Discussion. Risk factors for albuminuria that have been identified are age with adjusted odds ratio (AOR) 3.53 (1.41–8.83; p < 0.05), highest educational level with AOR 2.18 (1.14–4.17; p < 0.05), diabetes with AOR 3.36 (1.07–10.52; p < 0.05), and urinary cadmium with AOR 4.72 (2.33–9.59; p < 0.001), with future screening programs placing greater attention to those at risk and further research is required to determine the cause of exposure to cadmium

Elderly Abuse and Neglect on Population Health: Literature Review and Interventions from Selected Countries

Elderly abuse and neglect are among the primary public health problems linked to global demographic changes in the population, impacting not only the well-being of the elderly but also the growth of the nation or economy. This article discusses the effects of elder abuse and neglect on population health from the national and international perspectives through a narrative review of previously published articles on the concept of aging, the prevalence of elderly abuse and neglect, its risk factors and effects, and finally measures, legal perspectives, and recommendations to curb it. Interventions in Malaysia and selected nations, including Indonesia, South Korea, the United States, Australia, and Hong Kong, are examined. This issue is important as the majority of countries are moving toward being elderly populations. Improving global surveillance and the monitoring of instances is essential to inform policy actions to prevent elder abuse. In addition, a thorough assessment of the identified risk factors for violence and steps to prevent violence is required

Preliminary Study on Associated Risk Factors of Mortality Due to COVID-19 Pandemic in Malaysia

The COVID-19 pandemic has claimed numerous lives worldwide. Malaysia documented about 118 mortalities during the second wave of the outbreak. This study aims to assess associated risk factors of the COVID-19 mortalities from 18 March until 22 May 2020. The majority of patients were above 60 years old (69.0%), male (78.0%), and Malaysian citizens (98.0%). The mean age of the mortalities was 64.01 years old (±SD 14.91 years). The major risk factors consist of hypertension (52.0%), diabetes mellitus (43.0%), cardiovascular diseases (21.0%), extra-pulmonary solid malignancies (5.0%), cerebrovascular diseases (3.0%), pulmonary diseases (1.0%) and pulmonary malignancies (1.0%). About 23.0% of mortalities were related to established clusters while 5.0% had a history of travelling overseas. The mean survival time was 11.87 days (±SD 9.32 days). Approximately 50.0% of the patients survived until day 10 post-admission. The probability of the patients surviving beyond 30 days post-admission was less than 10.0%. There is a significant difference between groups for having a shorter duration to death for risk factors including age group, history of travelling overseas, attending mass gatherings, and having pulmonary malignancies. The hazard ratio (HR) for pulmonary malignancy is 5.512 (95% CI 0.662, 45.899), mass gathering; 3.434 (95% CI 1.375, 8.579), pulmonary disease is 2.442 (95% CI 0.314, 18.983), travelling overseas; 2.251 (95% CI 0.657, 7.711), extra-pulmonary solid malignancy; 2.165 (95% CI 0.767, 6.112), and despite the significant result only applied for mass gathering (p-value = 0.008). COVID-19 screening should be mandatory for those who attend mass gatherings as they are the main source of COVID-19 spread in the community during the second wave outbreak in Malaysia

Acute diarrhoea among under five years old children of underprivileged community in Kota Kinabalu, Sabah

The severity of childhood diarrhoea is linked with poor socioeconomic status, unhygienic living environment, and caregiver’s behaviour. This study is to determine the risk factors and economic burden associated with diarrhoea in children under 5 years of age. A case-control study using convenience sampling method with 105 cases and 105 controls was performed in Menggatal health clinic, Kota Kinabalu, Sabah between March-June 2017. Younger caregivers, without formal education, poor knowledge, practice handwashing with water only and stopped breastfeeding were associated with diarrhoea. Household with poor economic status, a family of five and more, crowded, with a pet, unsafe drinking water, no sanitary toilet, unsanitary garbage disposal and consuming streetvendor food also associated with diarrhoea. The mean of total direct costs, total indirect costs and total incurred costs were (Ringgit Malaysia) RM 9.70, RM 59.40, and RM 14.30, respectively. As a conclusion, the risk factors for diarrhoea under 5 years of age still presents in Sabah. Environmental factors and hygienic practice are needed to control under 5 diarrhoea