21 research outputs found
Haemorrhage - the main presenting feature of diverticular disease of the colon in blacks
Haemqrrhage is one of the less common presentations of diverticular disease. This retrospective 5 year study of 23 patients has identified it as the main presentation (74%) among South African blacks in whom the disease is uncommon, but emerging as a clinical problem. Women constituted a statistically significant majority of patients with bleeding (76%); this was in excess of their overall proportion among patients with diverticular disease (61%) (P =0,018)
A five-year audit of lower limb amputations below the knee and rehabilitation outcomes: The Durban experience
Introduction: Lower limb amputation (LLA) due to diabetes mellitus (DM) is a growing epidemic worldwide.Objectives: To determine the prevalence of LLAs at Addington Hospital from 2010 to 2014 and to explore the rehabilitation outcomes of amputees.Design and setting: A retrospective chart review of LLAs below the knee was undertaken at Addington Hospital.Subjects: Patients who underwent LLAs were filtered from theatre registers.Methodology: A data collection sheet included demographic profile, diabetic status, level of amputation, limb orientation and rehabilitation outcomes.Outcome measures: Study endpoints were prevalence, compliance and rehabilitation outcomes.Results: From 2010 to 2014, 767 LLAs in 667 patients were identified. Mean age was 59 (13.2) years. M:F ratio was 1:1. Of these, 354 patients (53.1%) had DM. Level of amputation was below-knee 57%, trans-metatarsal 12.4% and toectomy 30.6%. Only 116 patients (17.4%) were referred for physiotherapy, of whom 95 (81.9%) attended. Median frequency of physiotherapy visits was five and four for diabetic and non-diabetic amputees respectively. Mobility after rehabilitation was with a walking frame (49%), crutches (32%), prosthesis and crutches (8%), wheelchair-bound (9%) and independent gait (1%).Conclusion: Over half of amputations were associated with DM. The gender incidence was similar. Referral to physiotherapy and adherence there to was poor
Amoebic liver abscess - results of a conservative management policy
Objective. To evaluate the safety and efficacy of conservative management of amoebic liver abscesses.Design. A prospective study carried out over a 1-year period.Setting. Inpatients and outpatients in a tertiary referral institution.Subjects. Amoebic liver abscess was diagnosed on clinical, ultrasonographic, and serological features. All patients were treated with metronidazole. The indication for ultrasound guided aspiration of the abscess was failure to improve clinically within 48 - 72 hours.Main outcome measures. Clinical improvement, clinical deterioration and failure of clinical improvement (persistent pain).Results. In total 178 patients (male-to-female ratio 5:1) with 203 abscesses were treated during this period. Of these, 23 patients required percutaneous aspiration and 150 patients were managed without intervention and clinically resolved spontaneously. Abscesses requiring aspiration tended to be larger than those managed without aspiration (10.7 cm v. 8.2 cm) (p = 0.003). There were no complications following aspiration. Mean hospital stay was longer (12.3 days) for patients who underwent aspiration compared with those who did not (6. 7 days) (p = 0.031). Only 5 patients presented with ruptured abscesses, 1 cutaneously and 4 intraperitoneally, with the only death in this latter category.Conclusion. Conservative medical management of amoebic liver abscess is safe. Percutaneous ultrasound-guided aspiration is indicated only in patients who fail to improve clinically after 48 - 72 hours rather than on rigid criteria
A Comparison Of Preoperative Hypoalbuminaemia With The NNIS And SENIC Risk Scores For The Prediction Of Surgical Site Infection In A South African Setting
ArticleIntroduction: Preoperative hypoalbuminaemia is a risk factor for surgical site infection (SSI) in the South African (SA) setting. However,
the predictive accuracy of preoperative hypoalbuminaemia has not been tested against established SSI risk stratification models in
our setting, which could have important implications for SSI prevention strategies. With reference to SSI in SA settings, the study
objective was to compare the overall predictive accuracy of preoperative hypoalbuminaemia with that obtained for the SENIC/NNIS
risk scores.
Method: This was a sub-analysis of a pre-existing laparotomy patient registry (N = 439). Variables collected as part of the registry
included preoperative serum albumin measurements and all parameters of the SENIC/NNIS risk scores. Preoperative hypoalbuminaemia
was defined as preoperative serum albumin of < 30 g/L. The study outcome was SSI up to 30 days postoperatively. Overall predictive
accuracy was determined through a receiver-operator-characteristic (ROC) curve analysis, with results presented as C-statistics (95%
confidence intervals [CI]).
Results: The C-statistics obtained for preoperative hypoalbuminaemia, the SENIC risk score, and the NNIS risk score were 0.677
(CI: 0.609–0.746), 0.652 (CI: 0.582–0.721), and 0.634 (CI: 0.563–0.705).
Conclusion: All three methods display similar predictive accuracy for SSI. However, preoperative hypoalbuminaemia has several
practical advantages over the SENIC/NNIS scores which must be considered
Are Lower Preoperative Serum Sodium Levels Associated With Postoperative Surgical Site Infection? Results From A Propensity Matched Case-Control Study
ArticleBackground: We previously reported a statistical trend toward a harmful association between lower preoperative serum sodium
levels and surgical site infection (SSI) in South African (SA) laparotomy patients. Serum sodium tests are widely available and could
serve as a cost-effective method for preoperatively identifying patients at risk for SSI who might benefit from additional preventative
strategies. We sought to investigate the possible association between lower serum sodium levels and SSI further, in a larger sample of
SA patients undergoing various surgical procedures.
Objective: To determine if lower preoperative serum sodium levels are associated with SSI in SA surgical patients.
Method: This was a propensity matched case-control study involving data from 729 surgical patients who attended a quaternary
SA hospital between 01 January 2012 and 31 July 2016. Cases were defined as patients who developed SSI. Controls were defined as
patients who did not develop SSI. Multivariate logistic regression was used to investigate the association between preoperative serum
sodium levels (in mmol/L) and SSI.
Results: Lower preoperative serum sodium levels were associated with a higher risk of SSI (odds ratio per 1.0 mmol/L decrease in
serum sodium: 1.051, 95% confidence interval: 1.007–1.097; p = 0.026).
Conclusion: Although we report a statistically significant association between lower preoperative serum sodium levels and a higher
risk of SSI, the magnitude of this effect size (odds ratio) is minimal and clinically insignificant. Preoperative serum sodium levels are
unlikely to be useful for SSI risk stratification in our setting
Octupole correlations in the structure of O2 bands in the N=88 nuclei150Sm Gd
Knowledge of the exact microscopic structure of the 01
+ ground state and first excited 02
+ state in 150Sm is
required to understand the branching of double β decay to these states from 150Nd. The detailed spectroscopy of
150Sm and 152Gd has been studied using (α,xn) reactions and the γ -ray arrays AFRODITE and JUROGAM II.
Consistently strong E1 transitions are observed between the excited KĎ€ = 02
+ bands and the lowest negative
parity bands in both nuclei. These results are discussed in terms of the possible permanent octupole deformation
in the first excited KĎ€ = 02
+ band and also in terms of the “tidal wave” model of Frauendorf.Web of Scienc
Incisional Hernia: Experience in a Single Surgical Unit
Background: Incisional hernias are a common problem in general surgery
and they have a varied aetiology. The aim of this study was to document
a single unit experience with the management of incisional hernias at
King Edward VIII Hospital, Durban, South Arica. Patients and Methods:
This was a prospective audit of incisional hernias in a single surgical
unit from January 2001 to May 2004. All patients underwent open repair.
Clinical data and intra-operative findings were documented. Results: A
total number of 77 patients were seen of which 70 were female. Fifty
three (68.8%) and 24 (31.2%) of patients underwent elective and
emergency surgery respectively. A total of 56 patients had previously
undergone gynaecological surgery compared to 21 who had undergone
general surgery. There was a documented history of previous sepsis in 4
(7%) of patients. There was 1 sheath defect in 36 patients, 2 defects
in 9 patients, 3 defects in 10 patients, 4 or more defects in 9 cases.
In 55 patients the original suture could not be identified. Gangrenous
bowel was present in 3 patients. Only 3 (3.9%) of the patients had a
mesh repair. The rest (96.1%) underwent tissue repair. Morbidity rate
was 17% and there were no deaths. Five patients needed management in
the ICU. Hospital stay was 8 + 11 years Conclusion: Most incisional
hernias followed gynaecological surgery. There was no evidence of a
nonabsorbable suture having been used at the original operation in over
half of the patients. We recommend that meticulous technique is
essential in closing the abdominal incision
Blocking of coupling to the 0
The concept that the first excited 0+ states in N = 90 nuclei are not a -vibration but a second vacuum formed by the combination of the quadrupole pairing force and the low density of oblate orbitals near the Fermi surface is supported by the blocking of this collective mode in 154Gd from coupling to the [505]11/2- single-particle quasi-neutron orbital in 155Gd . The coupling of this orbital to the 2+
-vibration in 154Gd is observed since this coupling is not Pauli-blocked