Methyl (2Z)-2-({N-[2-(hy­droxy­meth­yl)phen­yl]-4-methyl­benzene­sulfonamido}­meth­yl)-3-phenyl­prop-2-enoate

In the title compound, C25H25NO5S, the O atom of the hy­droxy group is disordered over two positions, with occupancies of 0.820 (2) and 0.180 (2). The sulfonyl-bound benzene ring forms dihedral angles of 31.8 (1) and 60.7 (1)°, respectively, with the hy­droxy­methyl­benzene and phenyl rings. The mol­ecular conformation is stabilized by an intra­molecular O—H⋯O hydrogen bond, generating an S(8) ring motif. The crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds and C—H⋯π inter­actions

Methyl (2Z)-2-{[N-(2-formyl­phen­yl)-4-methyl­benzene­sulfonamido]­meth­yl}-3-(naphthalen-1-yl)prop-2-enoate

In the title compound, C29H25NO5S, the sulfonyl-bound benzene ring forms dihedral angles of 42.1 (1) and 48.5 (1)°, respectively, with the formyl-substituted benzene ring and the naphthalene residue. In the crystal, pairs of C—H⋯O inter­actions lead to the formation of R 2 2(10) inversion dimers, which are linked by further C—H⋯O inter­actions into supra­molecular tapes running along [100]. The crystal packing is further stabilized by C—H⋯π inter­actions

(Z)-Methyl 2-bromo­methyl-3-(2-chloro­phen­yl)acrylate

In the title compound, C11H10BrClO2, the dihedral angle between the benzene ring and the plane of the acrylate unit is 62.1 (1)°. The crystal packing is stabilzed by inter­molecular C—H⋯O hydrogen bonds and C—Cl⋯π inter­actions [Cl⋯centroid = 3.829 (1) Å and C—Cl⋯centroid = 165.3 (1)°]

Methyl (Z)-2-{[N-(2-formyl­phen­yl)-4-methyl­benzene­sulfonamido]­meth­yl}-3-phenyl­prop-2-enoate

In the title compound, C25H23NO5S, the sulfonyl-bound benzene ring forms dihedral angles of 37.2 (1) and 67.0 (1)°, respectively, with the formyl­phenyl and phenyl rings. The mol­ecular conformation is stabilized by an intra­molecular C—H⋯π inter­action. In the crystal, mol­ecules are linked by C—H⋯O hydrogen bonds, forming a two-dimensional network in the (110) plane in which R 4 4(38) ring motifs are generated

(Z)-Methyl 2-[(4-bromo-2-formyl­phen­oxy)meth­yl]-3-o-tolyl­acrylate

In the title compound, C19H17BrO4, the dihedral angle between the two benzene rings is 82.1 (1)°. The mol­ecular structure is stabilized by an intra­molecular C—H⋯O hydrogen bond which generates an S(7) ring motif. The crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds and C—H⋯π inter­actions. Inter­molecular C—H⋯O inter­actions are involved in the formation of centrosymmetric R 2 2(16) dimers, which are connected into supra­molecular tapes running along the [100] direction

(E)-Methyl 2-benzyl-3-o-tolyl­acrylate

In the title compound, C18H18O2, the methyl acrylate substituent adopts an extended E conformation with all torsion angles close to 180°. The mean plane of the acrylate unit and the phenyl ring are approximately orthogonal to each other, making a dihedral angle of 81.40 (6)°. The position of the carbonyl group with respect to the olefinic double bond is typically S-trans. The crystal packing is stabilized by inter­molecular C—H⋯π inter­actions

A bibliometric analysis of the 100 top-cited systematic review and meta-analysis in Orthodontics

ABSTRACT Objective: This bibliometric study aimed to analyze the citation metrics, journal and author characteristics, and subject domains of the 100 top-cited Systematic Reviews (SR) and Meta-Analysis (MA) in orthodontics. Material and Methods: An electronic database search was conducted for SR and MA in the Web of Science on 16th July 2023, without language and time restrictions. Of the 802 hits returned, the 100 top-cited orthodontic articles were shortlisted. They were analyzed for citation metrics, journal characteristics (journal, year of publication, impact factor-IF), author and affiliation characteristics (number, primary and corresponding author’s affiliation, and country), study domain, and keywords. Results: These articles were published from 1996 to 2021 in 20 journals, with an impact factor of 1.9 to 10.5, by 351 researchers affiliated with 104 universities. Their citations ranged from 45 to 344, and 34 poised to be classified as classic (≥ 100 citations). The maximum number of articles was published in the American Journal of Orthodontics and Dentofacial Orthopedics (n=38), the European Journal of Orthodontics (n=18), and the Angle Orthodontist (n=8). The authors for individual papers ranged from 1 to 10, with 5 being the most common (n=58). Europe had the highest contribution regarding the number of corresponding authors, institutions, and citations. Bone anchorage and orthodontic tooth movement/Biomechanics were the most frequently researched domains (n=11 each). The most common keyword used was Orthodontics (n=19), followed by Systematic Review (n=16) and Meta-analysis (n=9). Conclusion: In general, the top cited SR and MA were published in high-impact orthodontic journals, were multi-authored, and reflected the collaborative work from different universities

Evaluation of anti-microbial and anti-haemolytic activity of edible basidiomycetes mushroom fungi

Mushrooms are used for a variety of biotechnological applications, particularly for the production of food, enzymes, dietary supplements, pharmaceutical compounds, feed supplements. Basidiomycetes mushroom fungi have been known for their nutritional values they can be considered as functional foods which can provide health benefits beyond the traditional nutrients. Mushroom represents a major and untapped source of potent new pharmaceutical products. A wide range of activities including antitumour, cardiovascular and antimicrobial are reported in mushrooms. In developing countries like India mushroom progress is a boon in the field of food, medicine, and in generating employment. The alternative systems of medicine utilize the curative properties of mushrooms. They are also known to possess promising antioxidative, cardiovascular, hypercholesterolemia, antimicrobial, hepato-protective and anticancer effects. The present study aimed to evaluate antimicrobial and antihaemolytic activities of various extracts of Basidiomycetes mushroom fungi. Different Basidiomycetes mushroom fungi extracts (Hot water, Acetone and Hexane) were tested for antimicrobial and antihaemolytic activities. Among these different extracts of Basidiomycetes mushroom fungi the hexane extract of Pleurotus pulmonarius showed potential antimicrobial and antihaemolytic activity. The results of this study suggest the possibility of using Basidiomycetes mushroom fungi as natural sources for the pharmaceutical industry and could act as safe and cost-effective with potential biological activities. These findings encourage studying these fungal strains further for their potential biological applications

Composition analysis (pick analysis) of waste generated from household : A pilot study in Ujjain city, India

Waste segregation is an essential function in improving waste management. Waste segregation not only facilitates recycling and reduces waste going to landfills, rather it can benefit our environment and human in various ways. A pick analysis of waste composition is used to characterize the household waste stream and thus can analyze the segregation rate among the residents. In addition, it can measure the actual waste sorting behaviour at the household/community level. The objective of the study was to assess feasibility of a large-scale waste composition study, identify methodological and operational challenges, and estimate the resources needed to conduct the main waste composition study in order to obtain and get indicative figures about waste generation, composition, and miss-sorted proportions. The study team went door-to-door to collect waste in colour coded bags. We also collected the socio-demographic data of the households. The collected waste was weighed and segregated to analyze the waste composition. The analysis was done among 45 households, and it was found that the per capita waste generation per day is 0.25 kg (0.24 kg from slum and 0.27 kg from non-slum). Challenges identified in conducting waste composition study were lack of standard waste fraction classifications, difficulty in recruitment of personnel to conduct study due to social taboo around waste, challenge in co-coordinating with Ujjain Municipal Corporation waste collection vehicle for collection of waste. 53 household activities were completed in 5 and half hours with INR 24685 (USD 300.5). Pick analysis could be adopted by the Ujjain Municipal Corporation after cost effective analysis to generate precise estimate of waste generation, resource recovery, efficient resource allocation and will help in future interventions and informed policy decision making to improve segregation.Peer reviewe

Feasibility assessment of crowdsourcing slogans for promoting household waste segregation in India: a cross-sectional study

IntroductionCrowdsourcing is an emerging technique to engage or access a wider set of experts and multiple stakeholders through online platforms, which might effectively be employed in waste management. Therefore, we assessed the feasibility of the crowdsourcing method to provide an alternative approach that can improve household waste segregation using an “online-slogan-contest”.MethodsThe contest was promoted via targeted emails to various governmental and non-governmental organizations and through social media platforms for around 4 weeks (25 days). The entries were received through a Google form. The slogans were assessed by the experts and analyzed using content analysis methods.ResultsTotal 969 entries were received from different geographic regions in India. Of that, 456 were in English and 513 in Hindi. Five themes of waste segregation emerged from the received slogans: (1) Community awareness, responsibility, and support, (2) Significance of household waste segregation, (3) Use of separate dustbins, (4) Health and well-being, and (5) Environment and sustainability.DiscussionCrowdsourcing approaches can be used by local authorities for improving waste management approaches and are recommended as these involve a wider audience within a short time frame. Moreover, this approach is flexible and integrating crowdsourcing approaches strengthens our understanding of existing waste management activities