2 research outputs found
Research on BNCT in Poland and in the world
Przy Reaktorze MARIA w Narodowym Centrum Badań Jądrowych
(NCBJ) powstaje stanowisko do badań nad terapią
borowo-neutronową (BNCT). Terapia polega na napromienianiu
nowotworu wiązką neutronów o odpowiednich parametrach po
uprzednim podaniu pacjentowi związku boru, który w wyniku
określonych mechanizmów gromadzi się głównie w komórkach
rakowych. W wyniku reakcji 10B(n,α)7Li emitowane są cząstki
jonizujące powodujące zniszczenie tylko tych komórek, w których
zgromadzony jest bor [1]. Badania kliniczne prowadzone
na świecie potwierdzają skuteczność metody, otwierając nowe
perspektywy dla jej zastosowania w terapii konwencjonalnej.The stand for research on Boron Neutron Capture Therapy
(BNCT) at the MARIA Reactor at the National Centre for
Nuclear Research is being created. The therapy consists of irradiation
of the tumour with a neutron beam with specific parameters
after prior administration of the boron compound to the
patient, which accumulates mainly in cancer cells as a result of
specific mechanisms. As a result of 10B(n,α)7Li reaction, ionising
particles are emitted and destroy only those cells, in which boron
is accumulated. Clinical trials conducted in the world show
relatively high efficiency of BNCT, opening new perspectives for
its use in conventional therapy
MARIA Reactor Irradiation Technology Capabilities towards Advanced Applications
The MARIA research reactor is designed and operated as a multipurpose nuclear installation, combining material testing, neutron beam experiments, and medical and industrial radionuclide production, including molybdenum-99 (99Mo). Recently, after fuel conversion to LEU and rejuvenation of the staff while maintaining their experience, MARIA has been used to respond to the increased interest of the scientific community in advanced nuclear power studies, both fission and fusion. In this work, we would like to introduce MARIA’ s capabilities in the irradiation technology field and how it can serve future nuclear research worldwide