ASO Visual Abstract: Effect of Preoperative Home-Based Exercise Training on Quality of Life After Lung Cancer Surgery: A Multicenter Randomized Controlled Trial

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Effect of Preoperative Home-Based Exercise Training on Quality of Life After Lung Cancer Surgery: A Multicenter Randomized Controlled Trial

Background. Preoperative exercise training is recommended for improvement of clinical outcomes after lung cancer (LC) surgery. However, its efectiveness in preventing postoperative decline in quality of life (QoL) remains unknown. This study investigated the efect of preoperative home-based exercise training (PHET) on QoL after LC surgery. Methods. Patients awaiting LC resection were randomized to PHET or a control group (CG). The PHET program combined aerobic and resistance exercise, with weekly telephone supervision. Primary outcome was QoL-assessed with the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire C30 (QLQC30) at baseline, before surgery, and 1 month after surgery. The secondary outcomes were hospital length of stay and physical performance. The main analysis included a factorial repeated-measures analysis of variance. Additionally, the proportion of patients experiencing clinical deterioration from baseline to post-surgery was assessed. Results. The study included 41 patients (68.1±9.3 years; 68.3% male) in the intention-to-treat analysis (20 PHET patients, 21 CG patients). A signifcant group × time interaction was observed for global QoL (p =0.004). Betweengroup diferences in global QoL were statistically and clinically signifcant before surgery (mean diference [MD], 13.5 points; 95% confdence interval [CI], 2.4–24.6; p =0.019) and after surgery (MD, 12.4 points; 95% CI, 1.3–23.4; p=0.029), favoring PHET. Clinical deterioration of global QoL was reported by 71.4% of the CG patients compared with 30 % of the PHET patients (p =0.003). Between-group diferences in favor of PHET were found in pain and appetite loss as well as in physical, emotional and role functions after surgery (p <0.05). Compared with CG, PHET was superior in improving preoperative fve-times sit-to-stand and postoperative exercise capacity (p <0.05). No between-group diferences in other secondary outcomes were observed. Conclusion. The study showed that PHET can efectively prevent the decline in QoL after LC surgery.info:eu-repo/semantics/publishedVersio

AVALIAÇÃO DE ADUBOS PROTEGIDOS NA PRODUTIVIDADE DO MILHO

Resumo – O objetivo do trabalho foi avaliar a influência da adubação protegida no plantio com NPK e em cobertura com a utilização de KCl e ureia, em diferentes dosagens. O experimento foi conduzido na Fazenda São José, situada no município de Paracatu, MG. O delineamento experimental foi de blocos ao acaso, sendo compostos por vinte tratamentos (doses de adubos na base e em cobertura) e cinco repetições. A utilização da adubação protegida na cultura do milho incrementou a produtividade milho, com as ressalvas de doses e formas do NPK, ureia e KCl. Palavras-chave: Doses. Polímero.  Produtividade

Silício no crescimento e desenvolvimento de plantas de alface em cultivo fora do solo / Silence on growth and development of lettuce lettuce plants

O objetivo do trabalho foi avaliar os efeitos de concentrações de silício no crescimento e desenvolvimento de duas cultivares de alface em sistema de cultivo fora do solo. O experimento foi conduzido em casa de vegetação, no setor de Fitotecnia da UFSM. Os tratamentos foram compostos por cinco concentrações de silício na solução nutritiva: 0,0; 1,4; 2,8; 4,2 e 5,6 mmol L-1, duas cultivares (Stella e Veneranda) e pulverização foliar de silício aos sete dias antes da colheita. O delineamento experimental foi o inteiramente casualizado, com parcelas subdivididas, em esquema fatorial 5x2x2, com vinte e duas repetições. A maior massa fresca e seca da parte aérea foi observada para a cultivar Veneranda. O aumento da concentração de silício reduziu o crescimento e desenvolvimento das plantas de ambas as cultivares. Conclui-se que nas concentrações testadas não há efeito benéfico do silício na produção da alface em cultivo fora do solo

Direitos Autorais e Propriedade Intelectual na Era da Informação

Porto AlegreA coletânea é resultado de pesquisas de estudantes e professores do Programa de Pós-graduação em Ciência da Informação da Universidade Federal da Bahia. Apresenta um panorama sobre propriedade intelectual e suas ramificações, com ênfase nas questões de plágio e direitos autorais à luz da Ciência da Informação. Discute a produção artístico-cultural e o uso de conteúdos disseminados em plataformas digitais, evidenciando questões inerentes à multiplicação de dados e seu compartilhamento em multimeios. Sob a perspectiva da Ciência Aberta, a obra visa trazer novos olhares sobre os interesses que perpassam os direitos do autor, visando o interesse coletivo de difusão de saberes

Phosphorus Is Associated with Coronary Artery Disease in Patients with Preserved Renal Function

High serum phosphorus levels have been associated with mortality and cardiovascular events in patients with chronic kidney disease and in the general population. In addition, high phosphorus levels have been shown to induce vascular calcification and endothelial dysfunction in vitro. The aim of this study was to evaluate the relation of phosphorus and coronary calcification and atherosclerosis in the setting of normal renal function. This was a cross-sectional study involving 290 patients with suspected coronary artery disease and undergoing elective coronary angiography, with a creatinine clearance >60 ml/min/1.73 m2. Coronary artery obstruction was assessed by the Friesinger score and coronary artery calcification by multislice computed tomography. Serum phosphorus was higher in patients with an Agatston score >10 than in those with an Agatston score ≤10 (3.63±0.55 versus 3.49±0.52 mg/dl; p = 0.02). In the patients with Friesinger scores >4, serum phosphorus was higher (3.6±0.5 versus 3.5±0.6 mg/dl, p = 0.04) and median intact fibroblast growth factor 23 was lower (40.3 pg/ml versus 45.7 pg/ml, p = 0.01). Each 0.1-mg/dl higher serum phosphate was associated with a 7.4% higher odds of having a Friesinger score >4 (p = 0.03) and a 6.1% greater risk of having an Agatston score >10 (p = 0.01). Fibroblast growth factor 23 was a negative predictor of Friesinger score (p = 0.002). In conclusion, phosphorus is positively associated with coronary artery calcification and obstruction in patients with suspected coronary artery disease and preserved renal function

Energy Estimation of Cosmic Rays with the Engineering Radio Array of the Pierre Auger Observatory

The Auger Engineering Radio Array (AERA) is part of the Pierre Auger Observatory and is used to detect the radio emission of cosmic-ray air showers. These observations are compared to the data of the surface detector stations of the Observatory, which provide well-calibrated information on the cosmic-ray energies and arrival directions. The response of the radio stations in the 30 to 80 MHz regime has been thoroughly calibrated to enable the reconstruction of the incoming electric field. For the latter, the energy deposit per area is determined from the radio pulses at each observer position and is interpolated using a two-dimensional function that takes into account signal asymmetries due to interference between the geomagnetic and charge-excess emission components. The spatial integral over the signal distribution gives a direct measurement of the energy transferred from the primary cosmic ray into radio emission in the AERA frequency range. We measure 15.8 MeV of radiation energy for a 1 EeV air shower arriving perpendicularly to the geomagnetic field. This radiation energy -- corrected for geometrical effects -- is used as a cosmic-ray energy estimator. Performing an absolute energy calibration against the surface-detector information, we observe that this radio-energy estimator scales quadratically with the cosmic-ray energy as expected for coherent emission. We find an energy resolution of the radio reconstruction of 22% for the data set and 17% for a high-quality subset containing only events with at least five radio stations with signal.Comment: Replaced with published version. Added journal reference and DO

Measurement of the Radiation Energy in the Radio Signal of Extensive Air Showers as a Universal Estimator of Cosmic-Ray Energy

We measure the energy emitted by extensive air showers in the form of radio emission in the frequency range from 30 to 80 MHz. Exploiting the accurate energy scale of the Pierre Auger Observatory, we obtain a radiation energy of 15.8 \pm 0.7 (stat) \pm 6.7 (sys) MeV for cosmic rays with an energy of 1 EeV arriving perpendicularly to a geomagnetic field of 0.24 G, scaling quadratically with the cosmic-ray energy. A comparison with predictions from state-of-the-art first-principle calculations shows agreement with our measurement. The radiation energy provides direct access to the calorimetric energy in the electromagnetic cascade of extensive air showers. Comparison with our result thus allows the direct calibration of any cosmic-ray radio detector against the well-established energy scale of the Pierre Auger Observatory.Comment: Replaced with published version. Added journal reference and DOI. Supplemental material in the ancillary file