Acceso a las TIC de los estudiantes del Centro Universitario del Norte (CUNorte) ante la emergencia del COVID-19.

The health emergency generated by SARS-CoV2 has impacted in different ways the dynamics of higher education since the widespread closure, taking sanitary measures, social distance, and as a result, the suspension of face-to-face activities as a measure to prevent its spread. Information and Communications Technology (ICT) implementation is a challenge that students and professors face due to the orographic characteristics, connectivity, lack of computer equipment, and academic activities development preparation. In that sense, it is necessary to know the students' context about equipment and connectivity to assess their educational abilities; not all students have the best conditions to continue their educative process proving the digital divide that exists. This article references in particular to the Centro Universitario del Norte from Universidad de Guadalajara, where students' problems were analyzed on behalf COVID-19 pandemic in terms of ICT access and availability. The investigation design is descriptive and quantitative; it was found that the lack of access to ICT in Jalisco's North zone and Southern Zacatecas about accessibility and skills occurs in people who are in a low socioeconomic stratum and those who live in rural communities, being native students the most vulnerable.La emergencia sanitaria generada por el SARS-CoV2, ha impactado de diferentes maneras en las dinámicas de la educación superior, desde el cierre generalizado, la toma de medidas sanitarias, el distanciamiento social y como consecuencia la suspensión de actividades presenciales como medida para evitar su propagación. La implementación de las Tecnologías de la Información y la Comunicación (TIC), se constituye un desafío que enfrentan docentes y estudiantes por las características orográficas, de conectividad, falta de equipo de cómputo y preparación para el desarrollo de actividades académicas. En ese sentido es necesario conocer el contexto de los estudiantes con respecto al equipamiento y la conectividad para valorar el estado que guardan sus capacidades educativas, ya que, no todos los estudiantes cuentan con las mejores condiciones para continuar con su proceso educativo evidenciando la brecha digital que existe. Este trabajo hace referencia particularmente al Centro Universitario del Norte de la Universidad de Guadalajara, donde se analizó la problemática de los estudiantes ante la pandemia de COVID-19, relacionada con el acceso y la disponibilidad a las TIC. El diseño de la investigación es de corte cuantitativo descriptivo, se encontró que la falta de acceso a las TIC en la zona Norte de Jalisco y sur de Zacatecas sobre todo en términos de accesibilidad y habilidades ocurre en las personas que se encuentran en un estrato socioeconómico bajo y aquellas que viven en comunidades rurales, siendo los más vulnerables los estudiantes indígenas

Factores individuales que protegen o favorecen el riesgo de suicidio adolescente: estudio cualitativo con grupos focales

The aim of this study was to know the individual factors associated to risk and protection on suicide in adolescents from a high school from Universidad de Guadalajara, Mexico; from a students, teachers and psychotherapist view. Through a qualitative analysis of the information got in focus groups, have found that the main risk factors are depression, inadequate  emotional management and a lack of sense of life; while the protective factors from suicide are problem solving capacity, optimism and self-esteem. The findings are discussed from the support of specialized literature, and recommendations and practical implications are made.El objetivo del presente estudio fue conocer los factores individuales asociados al riesgo y protección ante el suicidio en adolescentes de una preparatoria de la Universidad de Guadalajara, México; desde la visión de estudiantes, profesores y terapeutas. Mediante un análisis cualitativo de la información obtenida a través de los grupos focales, se encontró que los principales factores de riesgo son la depresión, el manejo inadecuado de emociones y la carencia de un sentido de vida; mientras que los factores que protegen del riesgo suicida son, la capacidad de resolución de problemas, el optimismo y la autoestima. Los hallazgos se discuten desde el soporte de la literatura especializada, así mismo se realizan recomendaciones e implicaciones prácticas

S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo

BACKGROUND: Oxidative and nitrosative stress have been involved in gentamicin-induced nephrotoxicity. The purpose of this work was to study the effect of S-allylmercaptocysteine, a garlic derived compound, on gentamicin-induced oxidative and nitrosative stress and nephrotoxicity. In addition, the in vitro reactive oxygen species scavenging properties of S-allylmercaptocysteine were studied. RESULTS: S-allylmercaptocysteine was able to scavenge hydroxyl radicals and singlet oxygen in vitro. In rats treated with gentamicin (70 mg/Kg body weight, subcutaneously, every 12 h, for 4 days), renal oxidative stress was made evident by the increase in protein carbonyl content and 4-hydroxy-2-nonenal, and the nitrosative stress was made evident by the increase in 3-nitrotyrosine. In addition, gentamicin-induced nephrotoxicity was evident by the: (1) decrease in creatinine clearance and in activity of circulating glutathione peroxidase, and (2) increase in urinary excretion of N-acetyl-β-D-glucosaminidase, and (3) necrosis of proximal tubular cells. Gentamicin-induced oxidative and nitrosative stress and nephrotoxicity were attenuated by S-allylmercaptocysteine treatment (100 mg/Kg body weight, intragastrically, 24 h before the first dose of gentamicin and 50 mg/Kg body weight, intragastrically, every 12 h, for 4 days along gentamicin-treatment). CONCLUSION: In conclusion, S-allylmercaptocysteine is able to scavenge hydroxyl radicals and singlet oxygen in vitro and to ameliorate the gentamicin-induced nephrotoxicity and oxidative and nitrosative stress in vivo

Time course study of oxidative and nitrosative stress and antioxidant enzymes in K(2)Cr(2)O(7)-induced nephrotoxicity

BACKGROUND: Potassium dichromate (K(2)Cr(2)O(7))-induced nephrotoxicity is associated with oxidative and nitrosative stress. In this study we investigated the relation between the time course of the oxidative and nitrosative stress with kidney damage and alterations in the following antioxidant enzymes: Cu, Zn superoxide dismutase (Cu, Zn-SOD), Mn-SOD, glutathione peroxidase (GPx), glutathione reductase (GR), and catalase (CAT). METHODS: Nephrotoxicity was induced in rats by a single injection of K(2)Cr(2)O(7). Groups of animals were sacrificed on days 1,2,3,4,6,8,10, and 12. Nephrotoxicity was evaluated by histological studies and by measuring creatinine clearance, serum creatinine, blood urea nitrogen (BUN), and urinary excretion of N-acetyl-β-D-glucosaminidase (NAG) and total protein. Oxidative and nitrosative stress were measured by immunohistochemical localization of protein carbonyls and 3-nitrotyrosine, respectively. Cu, Zn-SOD, Mn-SOD, and CAT were studied by immunohistochemical localization. The activity of total SOD, CAT, GPx, and GR was also measured as well as serum and kidney content of chromium and urinary excretion of NO(2 )(-)/NO(3)(-). Data were compared by two-way analysis of variance followed by a post hoc test. RESULTS: Serum and kidney chromium content increased reaching the highest value on day 1. Nephrotoxicity was made evident by the decrease in creatinine clearance (days 1–4) and by the increase in serum creatinine (days 1–4), BUN (days 1–6), urinary excretion of NAG (days 1–4), and total protein (day 1–6) and by the structural damage to the proximal tubules (days 1–6). Oxidative and nitrosative stress were clearly evident on days 1–8. Urinary excretion of NO(2)(-)/NO(3)(- )decreased on days 2–6. Mn-SOD and Cu, Zn-SOD, estimated by immunohistochemistry, and total SOD activity remained unchanged. Activity of GPx decreased on days 3–12 and those of GR and CAT on days 2–10. Similar findings were observed by immunohistochemistry of CAT. CONCLUSION: These data show the association between oxidative and nitrosative stress with functional and structural renal damage induced by K(2)Cr(2)O(7). Renal antioxidant enzymes were regulated differentially and were not closely associated with oxidative or nitrosative stress or with kidney damage. In addition, the decrease in the urinary excretion of NO(2)(-)/NO(3)(- )was associated with the renal nitrosative stress suggesting that nitric oxide was derived to the formation of reactive nitrogen species involved in protein nitration

Kwapa: Gente del río. Estrategias transmedia de impacto social

El PAP Alter Código, período Primavera 2023, trabajó con los dos proyectos que se han venido trabajando en semestres anteriores: el videojuego A Orillas del río y el documental Déjennos pescar. Ambos proyectos parten de la metodología interdisciplinaria y colaborativa con miembros de la comunidad Cucapá para crear representaciones audiovisuales no estigmatizantes, que detonen el sentido de comunidad y refuercen su acervo cultural. El videojuego A Orillas del río es del género point and click, de vista isométrica, el cual está inspirado en el cuento oral tradicional El zorro y el coyote, que busca ser una herramienta lúdica de aprendizaje para reforzar el aprendizaje de la lengua Cucapá en los niños. Los resultados obtenidos fueron el demo del nivel uno (escenas uno y dos); colorimetría, arcos de personajes principales; programación de minijuegos. Dentro del documental ‘Déjennos pescar’ los resultados fueron un montaje, una clasificación del material grabado con transcripciones de audio, mientras que en la parte de estrategia de impacto se creó un manual de uso de redes sociales con colorimetría, tipografía, estilo de voz, tipo de contenido según la red social, para los futuros integrantes del equipo.ITESO, A.C