19 research outputs found
Research and application of coal exploration data management method in working face based on GIS
In order to improve the efficiency of dynamic calculation of coal reserves in the mining process of coal working face and enrich the dynamic updated data required in the construction of 3D geological model of working face in intelligent mining, a GIS based coal mining face data management method is proposed through the full analysis and in-depth research on the professional needs, business processes, technical routes and data structure of coal mining face data management. At the data level, the business process of coal exploration data management was optimized, the data structure and storage method of different types of coal exploration data were designed, the coal exploration data sharing and management of mining face based on spatial relational database were realized from using the spatial data organization and management mode. At the presentation level, the interactive management of coal exploration data and graphics was realized based on the domestic geographic information system platform, LongRuanGIS, independently developed from the bottom. At the business level, a drawing algorithm of coal exploration line was proposed to realize the rapid drawing of different coal exploration lines. The data structure, drawing style, drawing method and data management method of coal exploration point were designed to ensure the beautiful mapping of coal exploration data and efficient reuse of data; a method of dynamically updating the geological model of coal mining face by using the data of coal thickness detection was proposed, which enriches the dynamic updating data source of high-precision three-dimensional dynamic geological model of working face. The results of normalization application in many mines show that the management method of coal exploration data based on GIS realizes the unified management and sharing of different types of coal exploration data, realizes the rapid automatic mapping and dynamic updating of coal exploration data and improves the drawing efficiency of coal mine geologists. At the same time, the timely updating of coal exploration data provides convenient and effective data management measures for dynamic calculation of reserves and dynamic updating of high-precision 3D geological model, ensuring the efficient use of coal exploration data in many aspects
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Numerical investigation of GHz repetition rate fundamentally mode-locked all-fiber lasers
GHz repetition rate fundamentally mode-locked lasers have attracted great interest for a variety of scientific and practical applications. A passively mode-locked laser in all-fiber format has the advantages of high stability, maintenance-free operation, super compactness, and reliability. In this paper, we present numerical investigation on passive mode-locking of all-fiber lasers operating at repetition rates of 1-20 GHz. Our calculations show that the reflectivity of the output coupler, the small signal gain of the doped fiber, the total net cavity dispersion, and the modulation depth of the saturable absorber are the key parameters for producing stable fundamentally mode-locked pulses at GHz repetition rates in very short all-fiber linear cavities. The instabilities of GHz repetition rate fundamentally mode-locked all-fiber lasers with different parameters were calculated and analyzed. Compared to a regular MHz repetition rate mode-locked all-fiber laser, the pump power range for the mode-locking of a GHz repetition rate all-fiber laser is much larger due to the several orders of magnitude lower accumulated nonlinearity in the fiber cavity The presented numerical study provides valuable guidance for the design and development of highly stable mode-locked all-fiber lasers operating at GHz repetition rates.National Science Foundation Engineering Research Center for Integrated Access Networks [EEC-0812072]; Technology Research Initiative Fund (TRIF) Photonics Initiative of the University of Arizona; National Natural Science Foundation of China (NSFC) [61575075]Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
Bacteriophage-Resistant Mutants in Yersinia pestis: Identification of Phage Receptors and Attenuation for Mice
Background: Bacteriophages specific for Yersinia pestis are routinely used for plague diagnostics and could be an alternative to antibiotics in case of drug-resistant plague. A major concern of bacteriophage therapy is the emergence of phageresistant mutants. The use of phage cocktails can overcome this problem but only if the phages exploit different receptors. Some phage-resistant mutants lose virulence and therefore should not complicate bacteriophage therapy. Methodology/Principal Findings: The purpose of this work was to identify Y. pestis phage receptors using site-directed mutagenesis and trans-complementation and to determine potential attenuation of phage-resistant mutants for mice. Six receptors for eight phages were found in different parts of the lipopolysaccharide (LPS) inner and outer core. The receptor for R phage was localized beyond the LPS core. Most spontaneous and defined phage-resistant mutants of Y. pestis were attenuated, showing increase in LD 50 and time to death. The loss of different LPS core biosynthesis enzymes resulted in the reduction of Y. pestis virulence and there was a correlation between the degree of core truncation and the impact on virulence. The yrbH and waaA mutants completely lost their virulence. Conclusions/Significance: We identified Y. pestis receptors for eight bacteriophages. Nine phages together use at least seven different Y. pestis receptors that makes some of them promising for formulation of plague therapeutic cocktails. Most phage-resistant Y. pestis mutants become attenuated and thus should not pose a serious problem for bacteriophag
Physics-informed Student’s t mixture regression model applied to predict mixed oil length
Real-time estimation of thelength of mixed oil in a multi-product pipeline is a critical task during batch transportation. In previous studies, various predictive models have been built while they merely depended on a single predictive model to fulfill the regression work, and model performance severely deteriorated with the presence of outliers. The Student’s t mixture regression (SMR) model can identify multimode characteristics and reduce the impact of outliers. However, ignorance of physics knowledge and the simplistic assumption of a linear relationship between variables in the SMR may lead to unsatisfactory performance. In addition, the possible singularity problem can make the SMR fails to work. Motivated by resolving these issues, this paper proposes a physics-informed SMR modeling method by integrating the physics knowledge and the SMR to develop a robust hybrid predictive model for predicting the mixed oil length in a multi-product pipeline. Case studies are carried out on the measured dataset to demonstrate the effectiveness and advantages of the proposed new modeling method compared to the model entirely based on the SMR method and two state-of-the-art predictive models
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Wavelength Tunable Ho3+-Doped ZBLAN Fiber Lasers in the 1.2-mu m Wavelength Region
Wavelength tunability of continuous-wave holmium doped ZrF4-BaF2-LaT3-AlF3-NaF fiber lasers operating in the 1.2-arm wavelength region was investigated with a Littrow configuration. A wavelength tuning range of 1184-1198 nm was obtained from the fiber output port of the laser. The spectral width was measured to be around 0.02 nm over the entire tunable range and a maximum output power of 81.6 mW at 1192 nm was obtained at a pump power of 1.97 W. The wavelength tunable range was found to be limited by the transmission of the fiber-optic wavelength division multiplexer and coupler. A broader wavelength tuning range of 1177-1201 nm was obtained with a simpler fiber laser construction from the zero-order diffraction output of the bulk grating.NSF CIAN [EEC-0812072]; Photonics Initiative of University of Arizona; China Scholarship CouncilThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
A Camera Intrinsic Matrix-Free Calibration Method for Laser Triangulation Sensor
Laser triangulation sensors (LTS) are widely used to acquire depth information in industrial applications. However, the parameters of the components, e.g., the camera, of the off-the-shelf LTS are typically unknown. This makes it difficult to recalibrate the degenerated LTS devices during regular maintenance operations. In this paper, a novel one-dimensional target-based camera intrinsic matrix-free LTS calibration method is proposed. In contrast to conventional methods that calibrate the LTS based on the precise camera intrinsic matrix, we formulate the LTS calibration as an optimization problem taking all parameters of the LTS into account, simultaneously. In this way, many pairs of the camera intrinsic matrix and the equation of the laser plane can be solved and different pairs of parameters are equivalent for displacement measurement. A closed-form solution of the position of the one-dimensional target is proposed to make the parameters of the LTS optimizable. The results of simulations and experiments show that the proposed method can calibrate the LTS without knowing the camera intrinsic matrix. In addition, the proposed approach significantly improves the displacement measurement precision of the LTS after calibration. In conclusion, the proposed method proved that the precise camera intrinsic matrix is not the necessary condition for LTS displacement measurement.Applied Science, Faculty ofNon UBCEngineering, School of (Okanagan)ReviewedFacult
A comparative evaluation of the analytical performances of Capillarys 2 Flex Piercing, Tosoh HLC-723 G8, Premier Hb9210, and Roche Cobas c501 Tina-quant Gen 2 analyzers for HbA1c determination
Introduction: Haemoglobin A1c (HbA1c) is widely used in the management of diabetes. Therefore, the reliability and comparability among different analytical methods for its detection have become very important.
Materials and methods: A comparative evaluation of the analytical performances (precision, linearity, accuracy, method comparison, and interferences including bilirubin, triglyceride, cholesterol, labile HbA1c (LA1c), vitamin C, aspirin, fetal haemoglobin (HbF), and haemoglobin E (Hb E)) were performed on Capillarys 2 Flex Piercing (Capillarys 2FP) (Sebia, France), Tosoh HLC-723 G8 (Tosoh G8) (Tosoh, Japan), Premier Hb9210 (Trinity Biotech, Ireland) and Roche Cobas c501 (Roche c501) (Roche Diagnostics, Germany).
Results: A good precision was shown at both low and high HbA1c levels on all four systems, with all individual CVs below 2% (IFCC units) or 1.5% (NGSP units). Linearity analysis for each analyzer had achieved a good correlation coefficient (R2 > 0.99) over the entire range tested. The analytical bias of the four systems against the IFCC targets was less than ± 6% (NGSP units), indicating a good accuracy. Method comparison showed a great correlation and agreement between methods. Very high levels of triglycerides and cholesterol (? 15.28 and ? 8.72 mmol/L, respectively) led to falsely low HbA1c concentrations on Roche c501. Elevated HbF induced false HbA1c detection on Capillarys 2FP (> 10%), Tosoh G8 (> 30%), Premier Hb9210 (> 15%), and Roche c501 (> 5%). On Tosoh G8, HbE induced an extra peak on chromatogram, and significantly lower results were reported.
Conclusions: The four HbA1c methods commonly used with commercial analyzers showed a good reliability and comparability, although some interference may falsely alter the result