46 research outputs found
Ai-Empowered Inclusive Strategies for Fishing Villages
With the development of the economy and society, the continuous development and application of artificial intelligence have gradually become an important factor and driving force to promote the transformation and upgrading of all walks of life. Promoting artificial intelligence has inevitably become the best way to empower the governance and services of fishing village communities, which is also the general trend of future development. Artificial intelligence, as an organized force, plays an important role in community governance, but at present, the potential of artificial intelligence to empower community governance in fishing villages has not been fully tapped. Through literature survey, literature review and comparative analysis, this paper investigates and studies the current situation of community governance in artificial intelligence-empowered fishing villages, finds and raises some related problems. Then the survey found the significant role of artificial intelligence on community governance in fishing villages. Finally, according to the current situation of AI-empowered fishing village community governance, some constructive suggestions are put forward about AI-empowered inclusive strategies for fishing villages
Alzheimer Disease is Associated with Isotropic Ocular Enlargement
Recent studies have documented ocular changes in dementia patients,
especially Alzheimer Disease (AD). In this study, we explored the change of eye
size and eye shape in dementia, including AD patients. The eyeball volume and
diameters were estimated via T1-weighted brain magnetic resonance (MR) images
in the OASIS-3 database which included 83 AD, 247 non-AD dementiaand 336
normal-aging participants qualified for this study. After adjustment of age,
sex, race, apolipoprotein E genotypes, anisotropic ratio and intracranial
volume, we observed the eyeball volume of the AD group was significantly larger
than both the normal control (6871mm3 vs 6415mm3, p < 0.001) and the non-AD
dementia group (6871mm3 vs 6391 mm3, p < 0.001), but there was no difference
between the non-AD dementia group and the normal control (6391 mm3 vs 6415mm3,
p = 0.795). Similar results were observed for the axial, transverse and
vertical length. No group differences were observed in the anisotropic ratio,
indicating an isotropic volume increaseconsistent with previous changes induced
by the ocular hypertension (OH), which suggested possible elevation of the
intraocular pressure (IOP) in AD. In consideration of the recent findings in
ocular changes of dementia, our findings emphasize routine eye examinations and
eye cares for AD patients in the clinic
Intratumoral microbiome impacts immune infiltrates in tumor microenvironment and predicts prognosis in esophageal squamous cell carcinoma patients
BackgroundDifferent intratumoral microbiotaexist in different tumors and play a crucial function in carcinogenesis. However, whether they impact clinical outcomes in esophageal squamous cell carcinoma (ESCC) and their mechanism remain unclear.Methods16S rDNA amplicon sequencing was performed on surgically resected samples from 98 ESCC patients to analyze intratumoral microbiome abundance and composition. Multiplex fluorescent immunohistochemistry staining was used to profile the phenotypes of immune infiltrates in the tumor microenvironment (TME).ResultsPatients with higher intratumoral Shannon index had significantly worse surgical outcomes. When patients were divided into short-term survivors and long-term survivors based on the median survival time, both intratumoral alpha-diversity and beta-diversity were found to be significantly inconsistent, and the relative abundance of Lactobacillus and Leptotrichia emerged as the two microorganisms that probably influenced the survival of ESCC patients. Only Lactobacillus in ESCC was validated to significantly worsen patients’ prognoses and to be positively correlated with the Shannon index. Multivariate analysis revealed that the intratumoral Shannon index, the relative abundance of Lactobacillus, and the pathologic tumor–node–metastasis (pTNM) stage were independently associated with patients’ overall survival. Furthermore, the relative abundance of both Lactobacillus and Shannon index was positively correlated with the proportions of PD-L1+ epithelial cells (ECs) and tumor-associated macrophages (TAMs). The Shannon index was negatively correlated with the proportions of natural killer (NK) cells in the TME.ConclusionsA high abundance of intratumoral Lactobacillus and bacterial alpha-diversity was associated with the formation of the immunosuppressive TME and predicted poor long-term survival in ESCC patients
A Longitudinal Analysis about the Effect of Air Pollution on Astigmatism for Children and Young Adults
Purpose: This study aimed to investigate the correlation between air
pollution and astigmatism, considering the detrimental effects of air pollution
on respiratory, cardiovascular, and eye health. Methods: A longitudinal study
was conducted with 127,709 individuals aged 4-27 years from 9 cities in
Guangdong Province, China, spanning from 2019 to 2021. Astigmatism was measured
using cylinder values. Multiple measurements were taken at intervals of at
least 1 year. Various exposure windows were used to assess the lagged impacts
of air pollution on astigmatism. A panel data model with random effects was
constructed to analyze the relationship between pollutant exposure and
astigmatism. Results: The study revealed significant associations between
astigmatism and exposure to carbon monoxide (CO), nitrogen dioxide (NO2), and
particulate matter (PM2.5) over time. A 10 {\mu}g/m3 increase in a 3-year
exposure window of NO2 and PM2.5 was associated with a decrease in cylinder
value of -0.045 diopters and -0.017 diopters, respectively. A 0.1 mg/m3
increase in CO concentration within a 2-year exposure window correlated with a
decrease in cylinder value of -0.009 diopters. No significant relationships
were found between PM10 exposure and astigmatism. Conclusion: This study
concluded that greater exposure to NO2 and PM2.5 over longer periods aggravates
astigmatism. The negative effect of CO on astigmatism peaks in the exposure
window of 2 years prior to examination and diminishes afterward. No significant
association was found between PM10 exposure and astigmatism, suggesting that
gaseous and smaller particulate pollutants have easier access to human eyes,
causing heterogeneous morphological changes to the eyeball
Proton pitch angle distributions in the Martian induced magnetosphere: A survey of Tianwen-1 Mars Ion and Neutral Particle Analyzer observations
The pitch angle distributions of ions and electrons can be affected by various processes; thus, they can serve as an important indicator of the physical mechanisms driving the dynamics of space plasmas. From observations from the Mars Ion and Neutral Particle Analyzer onboard the Tianwen-1 orbiter, we calculated the pitch angle distributions of protons in the Martian induced magnetosphere by using information from the magnetohydrodynamically simulated magnetic field, and we statistically analyzed the spatial occurrence pattern of different types of pitch angle distributions. Even though no symmetrical features were seen in the dataset, we found the dominance of the field-aligned distribution type over the energy range from 188 to 6232 eV. Maps of the occurrence rate showed the preferential presence of a trapped-like distribution at the lower altitudes of the surveyed nightside region. Although our results are more or less restricted by the adopted magnetic field, they indicate the complexity of the near-Mars proton pitch angle distributions and infer the possibility of wave–particle interactions in the Martian induced magnetosphere
Modifying Anti-Compression Property and Water-Soluble Ability of Polyglycolic Acid via Melt Blending with Polyvinyl Alcohol
Biodegradable polymeric materials have become the most attractive research interest in recent years and are gradually widely used in various fields in the case of environmental pollution. In this paper, binary blends, mainly including varying contents of polyglycolic acid (PGA) and poly(vinyl alcohol) (PVA), were prepared via a melt compounding strategy. The ethylene-methyl acrylate-glycidyl methacrylate (EMA-GMA) was employed as the compatibilizer to improve the compatibility between the PGA and PVA and the polyolefin elastomer (POE) was used as toughening agent. The anti-compression property and water-soluble ability of the blends were particularly studied to explore their potential application in an oil/gas exploitation field. Special attentions were paid to the evolution of the water-soluble ability of PGAX with the PVA concentration. Furthermore, isothermal shear measurement and thermogravimetric analysis were performed to evaluate the thermal stability of PGA and PGA blends (PGAX) during melt processing. The results showed that the incompatibility between PGA and PVA largely deteriorated the mechanical property, i.e., anti-compression strength, leading to fragile characteristics under a lower compressive load for the PGAX samples with varied contents of PVA. The presence of PVA and EMA-GMA greatly enhanced the viscoelasticity of the PGA melt, showing an increased storage modulus and viscosity at a low shear frequency; however, the thermal instability of PGAX was intensified owing to the greater ease of thermal degradation of PVA than that of PGA. Meanwhile, the water-soluble ability of PGAX was improved due to the high water dissolution of PVA, which played the role as a sacrificial material. The purpose of this work is to pursue an effective modification for PGA processing and application via melt blending