Bipolar gold(III) complexes for solution-processable organic light-emitting devices with a small efficiency roll-off

Poster: no. 12A new class of bipolar alkynylgold(III) complexes containing triphenylamine and benzimidazole moieties has been synthesized and fully characterized. The incorporation of methyl groups in the central phenyl unit has been found to rigidify the molecule to reduce non-radiative decay, yielding a high photoluminescence quantum yield of up to 75 % in spin-coated thin films. More importantly, this class of alkynylgold(III) complexes exhibits excellent solubility in various organic solvents and is capable of serving as phosphorescent dopants in the fabrication of solution-processable organic lightemitting devices (OLEDs). Efficient solution-processable OLEDs with high external quantum efficiency (EQE) of up to 10 % and an extremely small efficiency roll-off of less than 1 % at a practical brightness of 1000 cd m–2 have been demonstrated.published_or_final_versio

Vers un processus continu d'extraction de connaissances à partir de textes

National audienceNous posons les bases d'un système continu, itéractif et interactif, d'extraction de connaissances à partir de textes. Le coeur de notre approche repose sur l'analyse formelle de concept. Elle permet de préserver le lien entre les textes et la conceptualisation du domaine, i.e. le treillis construit à partir des objets et des propriétés identifiés dans les textes. Les propriétés formelles du treillis sont exploitées pour suggérer à l'expert différentes stratégies lui permettant de modifier l'état courant de la conceptualisation. Le système calcule alors les modifications à apporter aux annotations textuelles pour qu'à l'itération suivante, le treillis intègre la modification souhaitée

Identifying the active ingredients of training interventions for healthcare professionals to promote and support increased levels of physical activity in adults with heart failure: a systematic review

Heart failure (HF) is characterised by breathlessness and fatigue that impacts negatively on patients’ intentions to prioritise physical activity (PA). Healthcare professionals (HCPs) experience challenges when motivating patients to increase PA. It is essential to develop an understanding of how to support HCPs to deliver PA interventions. We aimed to identify active ingredients of HCP training interventions to enable delivery of PA interventions to HF patients. Nine databases were searched. Data were extracted on study characteristics, active ingredients, outcomes, and fidelity measures. Data were synthesised narratively, and a promise analysis was conducted on intervention features. Ten RCTs, which reported a training intervention for HCPs were included (N = 22 HCPs: N = 1,414 HF patients). Two studies reported the use of theory to develop HCP training. Seven behaviour change techniques (BCTs) were identified across the 10 training interventions. The most ‘promising’ BCTs were ‘instruction on how to perform the behaviour’ and ‘problem solving’. Two studies reported that HCP training interventions had been formally evaluated. Fidelity domains including study design, monitoring and improving the delivery of treatment, intervention delivery, and provider training were infrequently reported. Future research should prioritise theory-informed development and robust evaluation of training interventions for HCPs to enable faithful and quality delivery of patient interventions

Comparison of fluorescence in-situ hybridisation with dual-colour in-situ hybridisation for assessment of HER2 gene amplification of breast cancer in Hong Kong

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Public understanding of COVID-19 antibody testing and test results: A qualitative study conducted in the U.K. early in the pandemic

Background: During the COVID-19 pandemic, antibody testing was proposed by several countries as a surveillance tool to monitor the spread of the virus and potentially to ease restrictions. In the UK, antibody testing originally formed the third pillar of the UK Government's COVID-19 testing programme and was thought to offer hope that those with a positive antibody test result could return to normal life. However, at that time scientists and the public had little understanding of the longevity of COVID-19 antibodies, and whether they provided immunity to reinfection or transmission of the virus. Objective: This paper explores the UK public's understanding of COVID-19 testing, perceived test accuracy, the meaning of a positive test result, willingness to adhere to restrictive measures in response to an antibody test result and how they expect other people to respond. Methods: On-line synchronous focus groups were conducted in April/May 2020 during the first wave of the pandemic and the most stringent period of the COVID-19 restrictive measures. Data were analysed thematically. Results: There was confusion in responses as to whether those with a positive or negative test should return to work and which restrictive measures would apply to them or their household members. Participants raised concerns about the wider public response to positive antibody test results and the adverse behavioural effects. There were worries that antibody tests could create a divided society particularly if those with a positive test result were given greater freedoms or chose to disregard the restrictive measures. Conclusion: Should these tests be offered more widely, information should be developed in consultation with the public to ensure clarity and address uncertainty about test results and subsequent behaviours

Building a Domain Knowledge Model Based on a Concept Lattice Integrating Expert Constraints

International audienceTraditionally, FCA can be used as a tool for eliciting from data a class schema in the form of either a set of attribute implications or a concept lattice. However, such a schema does not necessarily fit the point of view of a domain expert for different reasons, e.g. noise, errors or exceptions in the data. For example, in the domain of animals, an expert may expect that the rule "mammal implies do not lay eggs" holds, while this may not be the case if the platypus is among the objects in the formal context. In this paper, we propose to bridge the possible gap between the representation model based on a concept lattice and the representation model of a domain expert. The knowledge of the expert is encoded as a set of attribute dependencies or constraints which is "aligned" with the set of implications provided by the concept lattice, leading to modifications in the original concept lattice. The method can be generalized for generating lattices satisfying constraints based on attribute dependencies and using extensional projections. This method also allows the experts to keep a trace of the changes occurring in the original lattice and the revised version, and to assess how concepts in practice are related to concepts automatically issued from data

Factors associated with vaccine intention in adults living in England who either did not want or had not yet decided to be vaccinated against COVID-19

Early studies showed that 28–36% of UK adults were unsure or unwilling to be vaccinated against COVID-19. We wanted to identify which socio-demographic, socio-economic, personal health and psychological factors were associated with COVID-19 vaccine intentions (CVI) in adults living in England who did not want, yet to consider, or not sure whether to vaccinate. In October/November 2020, prior to vaccine availability, we surveyed adults stratified by gender, region, and deprivation, with additional purposive sampling of those aged 50 and over and those from an ethnic minority. Two hundred and ten did not want; 407 had yet to consider; and 1,043 were not sure whether to be vaccinated. Factors positively associated with CVI were: favorable vaccine views, trust in institutions associated with vaccine approval, vaccine subjective norms, anticipated regret of not having a vaccine, perceived vaccine benefits, perceived safety knowledge sufficiency, and a history of having an influenza vaccine. Factors negatively associated were: anti-lockdown views, and being a health or social care worker. Whilst showing significant relationships with CVI when analyzed in isolation, neighborhood deprivation and ethnicity did show an independent relationship to intention when all study measures were controlled for. Our findings suggest vaccine promotion focusing on the anticipated regret of not having a vaccine, the benefits of a mass COVID-19 immunization program, and the safety of a vaccine whilst ensuring or engendering trust in those bodies that brand a campaign may be most supportive of COVID-19 vaccine uptake