7 research outputs found

    Gene-Modified Tissue-Engineered Skin: The Next Generation of Skin Substitutes

    No full text

    Type 2 immunity and wound healing: evolutionary refinement of adaptive immunity by helminths

    No full text
    Helminth-induced type 2 immune responses, which are characterized by the T helper 2 cell-associated cytokines interleukin-4 (IL-4) and IL-13, mediate host protection through enhanced tissue repair, the control of inflammation and worm expulsion. In this Opinion article, we consider type 2 immunity in the context of helminth-mediated tissue damage. We examine the relationship between the control of helminth infection and the mechanisms of wound repair, and we provide a new understanding of the adaptive type 2 immune response and its contribution to both host tolerance and resistance
    corecore