4 research outputs found
Metabolomics-Based Discovery of Diagnostic Biomarkers for Onchocerciasis
- Author
- A Dabney
- A Hoerauf
- A Hoerauf
- A Hoerauf
- A Hoerauf
- AK Smilde
- AP Plaisier
- Ashlee A. K. Nunes
- B Crews
- BA Boatin
- BA Boatin
- CA Smith
- CA Smith
- EW Cupp
- EW Cupp
- FO Richards Jr
- G Dolce
- HM Bovelstad
- HR Taylor
- HR Taylor
- Hélène Carabin
- J Park
- J Saric
- JA Swets
- JE Bradley
- Judith R. Denery
- JV Li
- K Awadzi
- Kim D. Janda
- M Gomez Ravetti
- M Hall
- MA Rodriguez-Perez
- Mark S. Hixon
- MC Walsh
- MG Basanez
- MY Osei-Atweneboana
- N Vinayavekhin
- P Stingl
- R Jornsten
- S Baek
- S Karlsson
- S Ritchie
- S Specht
- TA Lasko
- Tobin J. Dickerson
- TS Churcher
- Y Dadzie
- Y Wang
- Y Wang
- Z Zhang
- Publication venue
- Public Library of Science
- Publication date
- 05/10/2010
- Field of study
Onchocerciasis, caused by the filarial parasite Onchocerca volvulus, afflicts millions of people, causing such debilitating symptoms as blindness and acute dermatitis. There are no accurate, sensitive means of diagnosing O. volvulus infection. Clinical diagnostics are desperately needed in order to achieve the goals of controlling and eliminating onchocerciasis and neglected tropical diseases in general. In this study, a metabolomics approach is introduced for the discovery of small molecule biomarkers that can be used to diagnose O. volvulus infection. Blood samples from O. volvulus infected and uninfected individuals from different geographic regions were compared using liquid chromatography separation and mass spectrometry identification. Thousands of chromatographic mass features were statistically compared to discover 14 mass features that were significantly different between infected and uninfected individuals. Multivariate statistical analysis and machine learning algorithms demonstrated how these biomarkers could be used to differentiate between infected and uninfected individuals and indicate that the diagnostic may even be sensitive enough to assess the viability of worms. This study suggests a future potential of these biomarkers for use in a field-based onchocerciasis diagnostic and how such an approach could be expanded for the development of diagnostics for other neglected tropical diseases
Mitochondrial DNA analysis of eneolithic trypillians from Ukraine reveals neolithic farming genetic roots
- Author
- A Pelisiak
- A Szécsényi-Nagy
- A Torroni
- A V Nedoluzhko
- AG Nikitin
- AG Nikitin
- AG Nikitin
- AG Nikitin
- AG Nikitin
- Alexey G. Nikitin
- AS Sokolov
- C Gamba
- C Posth
- C Santos
- Cristian Capelli
- David Reich
- Domínguez E Fernández
- DW Anthony
- E Fernández
- EJ Lee
- G Brandt
- H Malmström
- H Malmström
- I Mathieson
- ID Potekhina
- ID Potekhina
- Inna Potekhina
- J Dabney
- J Müller
- M Knapp
- M Lacan
- M Lacan
- M Lillie
- M Pala
- Malcolm Lillie
- MY Videiko
- N Rohland
- Nadin Rohland
- P Brotherton
- P Korlević
- P Skoglund
- P Skoglund
- Q Fu
- RM Andrews
- SP Segeda
- Swapan Mallick
- VA Dergachev
- VG Zbenovich
- VV Khvoika
- W Haak
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Uptake, Transport and Emission of Ammonia by the Plants
- Author
- A Bytnerowicz
- A Fangmeier
- A Gebler
- A Geßler
- A Oaks
- AD Glass
- AD Glass
- AJ Termorshuizen
- AW Vermetten
- B Muller
- CA Stutte
- CE Jung
- CM Reynolds
- CO Tamm
- D Baurer
- D Dam
- DA Hegg
- DC Adriano
- DC Whitehead
- DR Lockyear
- DR Lockyear
- DW Cowling
- E Meszaros
- E Witter
- E Witter
- EJ Wilson
- F Dubois
- FR Lauter
- G Bonazzi
- G Hoek
- G Mack
- G Ochs
- GA Dowson
- GL Grundmann
- GL Hutchinson
- GT Heij
- HF Dijk
- HJ Kronzucher
- HM Lam
- HS Srivastava
- J Finnemann
- J Pearson
- J Woodall
- JA Raven
- JB Pate
- JM Clement
- JS Levine
- K Kamachi
- KC Bangar
- KR Reddy
- L Horvath
- L Stibe
- LJ Eerden
- LJ Eerden
- LJ Trueman
- LK Porter
- LW Hove
- LW Hove
- LW Hove
- M Kam
- M Kaupenjohann
- M Kithome
- M Mattsson
- M Mattsson
- M Perez-Soba
- M Perez-Soba
- M Pietila
- MA Rouf
- MB Ali
- MD Cramer
- ML Shuler
- MY Siddiqui
- MY Wang
- N Yamamoto
- NF Gmur
- NM Crawford
- O. Ninnemann
- PA Moore
- PJ Lea
- PW Westerman
- R Bobbink
- R Tanner
- RB Lee
- RB Thompson
- RC Hansen
- RC Leegood
- RM Harrison
- RM Wallsgrove
- RS Siegel
- S Husted
- S Husted
- S Mahimairaja
- S. Schmidt
- SG Sommer
- SG Sommer
- SG Sommer
- SM Dabney
- T Al-Kanani
- TA Dueck
- TS Steenhuis
- V Buchanan-Wollaston
- W Fluckiger
- WA Asman
- WA Asman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2000
- Field of study
Ovarium, Hypophyse, Placenta und Schwangerschaft in ihrer innersekretorischen Beziehung zur Frauenheilkunde
- Author
- A Albertz
- A Arvay v
- A Berblinger
- A Bergamini
- A Biedl
- A Biedl
- A Biedl
- A Biedl
- A Biedl
- A Biedl
- A Biedl
- A Bourne
- A Bourne
- A Bourne
- A Bourne
- A Brindeau
- A Brindeau
- A Brindeau
- A Brindeau
- A Brindeau
- A Brindeau
- A Brindeau
- A Brouha
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Butenandt
- A Capecchi
- A Egoroff
- A Egoroff
- A Fortunato
- A Gaeta di
- A Garcia
- A Girard
- A Girard
- A Girard
- A J ores
- A Jores
- A Jores
- A Jores
- A Jores
- A Jores
- A Kostic
- A Latzka von
- A Leimdörfer
- A Lejwa
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Lipschütz
- A Loeser
- A Loeser
- A Loeser
- A Loeser
- A Loeser
- A Loewe
- A Mahnert
- A Mahnert
- A Mahnert
- A Mandelstamm
- A Mandelstamm
- A Mandelstamm
- A Mandelstamm
- A Mayer
- A Probstner
- A Probstner
- A Probstner
- A Probstner
- A PujohBrüll
- A Schittenhelm
- A Schittenhelm
- A Schulcz
- A Seitz
- A Seitz
- A Seitz
- A Siddall
- A Slonaker
- A Tierny
- A Trendelenburg
- A Westman
- A Westman
- A Westman
- A Westman
- A Westman
- A Westman
- A Westman
- A Westman
- A Weymeersch
- A Weymeersch
- A Weymeersch
- AA Adler
- AA Adler
- AA Hellbaum
- AA Werner
- AA Werner
- Abel
- AC Sidall
- AD Campbell
- AD Campbell
- AE Laszo
- AG Kling
- AI Crainicianu
- AJ McLean
- AJ Ziserman
- AM Agaronow
- Anselmino
- AR Fee
- AR Fee
- AS Parkes
- AS Parkes
- AS Parkes
- AS Parkes
- AS Parkes
- AS Parkes
- AW Netto
- AWM Pompen
- AWM Pompen
- AWM Pompen
- B Aschner
- B Aschner
- B Aschner
- B Bloch
- B Bloch
- B Frattini
- B Hopman
- B Lörincz
- B Mann
- B Ofstad
- B Parvey
- B Putnam
- B Weber
- B Weil
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- B Zondek
- BA Houssay
- BE Brüda
- BJ Stepowski
- BJ Stepowski
- BO Barnes
- BP Wiesner
- C Benda
- C Champy
- C Clauberg
- C Clauberg
- C Clauberg
- C Clauberg
- C Clauberg
- C Clauberg
- C Clauberg
- C Clauberg
- C Clauberg
- C Daniel
- C Fesmo de
- C Froboese
- C Funk
- C Gianella
- C Hamburger
- C Hamburger
- C Hamburger
- C Hamburger
- C Hamburger
- C Hamburger
- C Hamburger
- C Hamburger
- C Hamburger
- C Hartmann
- C Kaufmann
- C Kaufmann
- C Kaufmann
- C Kaufmann
- C Lorca
- C Lorca
- C Mazer
- C Mazer
- C Mazer
- C Moore
- C Muto
- C Muto
- C Muto
- C Rüge
- C Stockard
- Castex
- CD Veler
- CD Veler
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CF Fluhmann
- CG Hartman
- CG Hartman
- CG Hartman
- CG Hartman
- CH Herrick
- Chevrel-Bodin
- CP Richter
- CR Moore
- CR Moore
- CW Bellerby
- CW Turner
- D Edwards
- D Gostimirovicz
- D Gostimirovicz
- D Gostimirovicz
- D Gostimirovió
- D Lewis
- D Raise
- D Riddle
- D Steinach
- DC Robertson
- Delgado
- DJ Macht
- DM Stern
- Dohrn
- E Allen
- E Allen
- E Allen
- E Allen
- E Allen
- E Allen
- E Allen
- E Allen
- E Allen
- E Allen
- E Allen
- E Ammon
- E Borchardt
- E Borchardt
- E Borchardt
- E Brandstrup
- E Dahl-Iversen
- E Dahl-Iversen
- E Dingemanse
- E Dingemanse
- E Dingemanse
- E Dingemanse
- E Dingemanse
- E Dingemanse
- E Dingemanse
- E Engelhardt
- E Engelhart
- E Engle
- E Engle
- E Fauvet
- E Fauvet
- E Fauvet
- E Fels
- E Fels
- E Fels
- E Fels
- E Fels
- E Fels
- E Forto
- E Gilardino
- E Glimm
- E Glimm
- E Glimm
- E Glimm
- E Glimm
- E Imparato
- E Kulka
- E Kulka
- E Laqueur
- E Laqueur
- E Laqueur
- E Laqueur
- E Laqueur
- E Laqueur
- E Margitay-Becht
- E Maurizio
- E Moller-Christensen
- E Novak
- E Novak
- E Parache
- E Philipp
- E Philipp
- E Philipp
- E Philipp
- E Philipp
- E Philipp
- E Philipp
- E Preißecker
- E Raab
- E Schwenk
- E Steinach
- E Steinach
- E Steinach
- E Tóth
- E Vogt
- E Vogt
- E Waldstein
- E Wehefritz
- E Wehefritz
- E Wehefritz
- EA Doisy
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- EJ Evans
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- EL Corey
- EM Anderson
- EM Scarborough
- EP Bugbee
- ET Engle
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- EW Winter
- EW Winter
- EW Winter
- F Bachner
- F Bentivoglio
- F Bühler
- F Carreras
- F Consoli
- F Curtis
- F Eberson
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- F Grueter
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- F Haurowitz
- F Haurowitz
- F Hoffmann
- F Hoffmann
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- F Hoffmann
- F Hoffmann
- F Laquer
- F Ludwig
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- F Schörcher
- F Settergren
- F Siegert
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- F Siegert
- F Siegert
- F Siegert
- F Silberstein
- F Silberstein
- F Spielman
- F Spielman
- F Verzär
- F Voban
- F Vozza
- F Vozza
- F Wadehn
- F Wermbter
- FA Ford
- FAE Crew
- Fauvet
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- G Amati
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- GF Fluhmann
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- Leschke
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- Liebesny
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- Loeser
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- M Boschetti
- M Daje
- M Davis
- M Dohm
- M Dohrn
- M Dohrn
- M Ferro
- M Geyer
- M Geyer
- M Gutman
- M Heckmann
- M Hill
- M Hill
- M Hill
- M Hill
- M Hill
- M Hill
- M Hill
- M Ito
- M Ito
- M Klein
- M Klein
- M Klein
- M Klein
- M Klein
- M Knell
- M Kochmann
- M Krogh
- M Loeper
- M Maino
- M Maino
- M Massazza
- M Murata
- M Murata
- M Pick
- M Pick
- M Reeb
- M Reiss
- M Reiss
- M Reiss
- M Reiss
- M Reiss
- M Reiß
- M Reiß
- M Reiß
- M Reiß
- M Testa
- M Trancu-Rainer
- M Traneu-Rainer
- M Trettenero
- M Trettenero
- M Trettenero
- M Trettenero
- M Vesell
- MA Castalio
- MA Goldberger
- MA Gsell-Busse
- MA Magath
- MA Magath
- Mathei
- Mathei
- Mazer
- MB Handelsman
- MB Handelsman
- MC Shelesnyak
- MC Westerman
- McGee
- ME Davis
- MH Friedman
- MH Friedman
- MH Friedman
- MH Friedman
- MH Friedmann
- MH Friedmann
- MH Friedmann
- MI Smith
- MK McPhail
- MK McPhail
- MK McPhail
- MK McPhail
- ML Leventhal
- ML Shelesnyak
- MM Kunde
- MP Nikolaeff
- MP Nikolaeff
- MR Becker
- MR Becker
- MR White
- MY Dabney
- N Candela
- N Candela
- N Candela
- N Candela
- N Fiessinger
- N Fiessinger
- N Goormghtigh
- N Reeb
- Nizescu
- O Aichel
- O Bokelmann
- O Bokelmann
- O Busse
- O Contreras
- O Corner
- O Fahlbusch
- O Fellner
- O Fellner
- O Fellner
- O Fellner
- O Fellner
- O Fellner
- O Fellner
- O Hirsch
- O Kamm
- O Lewis
- O Mühlbock
- O Riddle
- O Riddle
- O Riddle
- O Riddle
- O Riddle
- O Riddle
- O Riddle
- O Riddle
- P Caffier
- P Damm
- P Damm
- P Engel
- P Ferriguo
- P Ferriguo
- P Fremery de
- P Fremery de
- P Fremery de
- P Fremery de
- P Gley
- P Glud
- P Hauptstein
- P Hauptstein
- P Hauptstein
- P Hauptstein
- P Hauptstein
- P Hauptstein
- P Luziani
- P Machteld
- P Noether
- P Noether
- P Pensa
- P Rochet
- P Schugt
- P Smith
- P Sä
- P Tagliaferro
- P Wirz
- P Wirz
- PA Katzman
- PA Katzman
- Parkes
- PB Bland
- PC Antonio
- PE Borras
- PE Borräs
- PE Morhardt
- PE Morhardt
- PE Morhardt
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PE Smith
- PF Nigst
- PF Schneider
- PF Schneider
- Philipp
- PL Drouet
- PMF Bishop
- Prenant
- R Bompiani
- R Bourg
- R Bourg
- R Bourg
- R Bourg
- R Brühl
- R Brühl
- R Brühl
- R Brühl
- R Courier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Courrier
- R Deanesly
- R Deanesly
- R Goodman Le
- R Hertz
- R Hertz
- R Joachimovits
- R Kurzrok
- R Meyer
- R Meyer
- R Moricard
- R Neumann
- R Schröder
- R Schröder
- R Schröder
- R Schröder
- R Schröder
- R Schröder
- R Schwarcz
- RA Lifvendahl
- RE Illingworth
- Reeb
- Reynolds
- RH Jones
- RI Pencharz
- RK Meyer
- RK Meyer
- RK Meyer
- RK Meyer
- Rowe
- RP Frank
- RS Ferguson
- RT Frank
- RT Frank
- RT Frank
- RT Frank
- RT Frank
- RT Frank
- RT Frank
- RT Frank
- RT Frank
- RT Frank
- S Aschheim
- S Aschheim
- S Aschheim
- S Aschheim
- S Aschheim
- S Aschheim
- S Aschheim
- S Aschheim
- S Aschheim
- S Aschheim
- S Aschheim
- S Asdell
- S Barjaktarevie
- S Calvar
- S Cikowski
- S Felding
- S Glaubach
- S Hayashi
- S Janssen
- S Janssen
- S Janssen
- S Joseph
- S Kawanobe
- S Kober
- S Kober
- S Kober
- S Kober
- S Konsuloff
- S Konsulofft
- S Loewe
- S Loewe
- S Loewe
- S Loewe
- S Loewe
- S Loewe
- S Loewe
- S Loewe
- S Loewe
- S Rosenfeld
- S Saiki
- S Scaglione
- S Scaglione
- S Skowron
- S Stammler
- S stein
- S Szarka
- S Thayer
- S Thayer
- S Trendelenburg
- S Veshnjakov
- S Zocchi
- S Zocchi
- SD Soule
- SD Soule
- SE Jongh de
- SE Jongh de
- SE Jongh de
- SE Jongh de
- SE Jongh de
- SE Jongh de
- SE Jongh de
- SE Jongh de
- SE Jongh de
- SE Jongh de
- SH Geist
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- SL Leonard
- Snoode
- SRM Reynolds
- SRM Reynolds
- SRM Reynolds
- SS Barjaktarovic
- Strieker
- Szarka
- T Bunnag
- T Fellenberg
- T Garcia
- T Kuchaarski
- T Kunischige
- T Leegaard
- T Martins
- T Martins
- T Shirai
- TB Magath
- TC Sherwood
- TF Gallagher
- TF Gallagher
- TK Brown
- TL Squier
- TNA Jeffcoate
- Trautmann
- Trendelenburg
- Trendelenburg
- Treuter
- V Hormone
- V Korenchevsky
- v Mikulicz-Radecki
- Voegtlin
- W Berblinger
- W Berblinger
- W Berblinger
- W Berblinger
- W Bickenbach
- W Büngeler
- W Büttner
- W Filler
- W Fleischmann
- W Grab
- W Grab
- W Grab
- W Grab
- W Hartmann
- W Hoffmann
- W Hohlweg
- W Hohlweg
- W Hohlweg
- W Hohlweg
- W Hohlweg
- W Kennedy
- W Kestranek
- W Lampe
- W Nieuwenkamp
- W Reiprich
- W Reiprich
- W Reiprich
- W Reiprich
- W Rosenthal
- W Scheringer
- W Scheringer
- W Schoeller
- W Schoeller
- W Schoeller
- W Schoeller
- W Schoeller
- W Schoeller
- W Schoeller
- W Schoeller
- W Schoeller
- W Schäper
- W Spitzer
- W Stewart
- W Österreicher
- W Österreicher
- W Österreicher
- WB Bell
- WB Draper
- WB Payne
- WE White
- WE White
- WK Tschaikowsky
- WKT schaikowsky
- WM Allen
- WM Allen
- WM Allen
- WM Allen
- WM Allen
- WM Allen
- WM Allen
- WM Allen
- WM Allen
- WM Firor
- WM Firor
- WO Nelson
- WO Nelson
- WO Nelson
- WP Maddux
- WR Henderson
- WR Lyons
- WR Lyons
- WR Lyons
- Z Wallen-Lawrence
- Z Wallen-Lawrence
- Z Wallen-Lawrence
- Zondek
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1936
- Field of study