20 research outputs found
Unusually high‐quality soil seed banks in a Midwestern U.S. oak savanna region: variation with land use history, habitat restoration, and soil properties
Evaluation of the novel non-invasive zero-heat-flux Tcore™ thermometer in cardiac surgical patients
Le génotype epsilon 4 de l’apolipoprotéine est associé à une moindre amélioration de la fonction cognitive cinq ans après chirurgie cardiaque: une étude rétrospective de cohorte
Berberine promotes the development of atherosclerosis and foam cell formation by inducing scavenger receptor A expression in macrophage
Efficacy of functional foods mixture in improving hypercholesterolemia, inflammatory and endothelial dysfunction biomarkers-induced by high cholesterol diet
Can Butterflies Evade Fire? Pupa Location and Heat Tolerance in Fire Prone Habitats of Florida
A Wnt-mediated phenotype switch along the epithelial–mesenchymal axis defines resistance and invasion downstream of ionising radiation in oral squamous cell carcinoma
New data on the stem and leaf anatomy of two conifers from the Lower Cretaceous of the Araripe Basin, northeastern Brazil, and their taxonomic and paleoecological implications
The role of the epithelial-to-mesenchymal transition (EMT) in diseases of the salivary glands
The link between inflammatory microenvironment and cancer emerged in the last years as a decisive factor in the induction of the pathological epithelial-mesenchymal transition (EMT). The EMT induces changes of cell states converting the epithelial cells to mesenchymal cells when this program is fully executed and EMT has emerged as a central driver of tumor malignancy. Cellular pathways activated by chronic inflammation brought about by chronic infections, by immune-mediated diseases, or by dysregulated wound healing at sites of repetitive tissue injury, constitute risk factors or initial cell transformation and for cancer progression. EMT and its intermediate states have recently been identified as crucial inducers of organ fibrosis, inflammation and tumor progression. In this review, we discuss the current state-of-the-art and latest findings regarding the link between EMT, inflammation, fibrosis and cancer, highlighting the most recent data on EMT-dependent tissue fibrosis during chronic inflammatory salivary glands conditions and salivary glands tumors