From Petroleum to Bio-Based Solvents: From Academia to Industry

International audienceThe property and applications of bio-based solvents in place of petroleum-based ones for natural product extractions are discussed in this chapter including vegetable oils, terpenes, 2-methyltetrahydrofuran, bio-ethanol and natural deep eutectic solvents (NADES). Several commonly used prediction techniques such as Hansen solubility parameters (HSP), COnductor-like Screening MOdel for Real Solvents (COSMO-RS) and life-cycle assessment (LCA) are introduced to evaluate theoretical solubility and environmental impacts during all stages of a solvent’s life. Besides, the revisit of polar paradox theory helps us to better understand the solubilization mechanism underpinning the extraction. This chapter is intended to describe not only past and current achievements and challenges, but also to give visions for more sustainable applications in this increasingly important field of chemistry. Finally, it is also intended to draw the way to more rigorous research going beyond empiricism, which is still the usual approach in plant extractions

Downstream green processes for recovery of bioactives from algae

Nowadays, macro- and microalgae are being increasingly used as promising raw materials for the food, cosmetic and pharmaceutical industries, thanks to their biodiversity and its variety on valuable bioactive compounds such as carbohydrates, polyunsaturated lipids, proteins and pigments, among others. Furthermore, more efficient and environmentally friendly processes for bioactives’ recovery are requested not only by the industry but also by the society. This chapter presents an overview on the use of downstream green processes, mainly based on compressed fluids extraction techniques, in order to recover bioactives from algae that can be lately used in several potential applications for the food, pharmaceutical and cosmetic industries, which is the pillar of algae-based biorefinery.Peer reviewe