203 research outputs found
Pool inference attacks on local differential privacy: quantifying the privacy guarantees of apple's count mean sketch in practice
Behavioral data generated by users’ devices, ranging from emoji use to pages visited, are collected at scale to improve apps and services. These data, however, contain fine-grained records and can reveal sensitive information about individual users. Local differential privacy has been used by companies as a solution to collect data from users while preserving privacy. We here first introduce pool inference attacks, where an adversary has access to a user’s obfuscated data, defines pools of objects, and exploits the user’s polarized behavior in multiple data collections to infer the user’s preferred pool. Second, we instantiate this attack against Count Mean Sketch, a local differential privacy mechanism proposed by Apple and deployed in iOS and Mac OS devices, using a Bayesian model. Using Apple’s parameters for the privacy loss ε, we then consider two specific attacks: one in the emojis setting — where an adversary aims at inferring a user’s preferred skin tone for emojis — and one against visited websites — where an adversary wants to learn the political orientation of a user from the news websites they visit. In both cases, we show the attack to be much more effective than a random guess when the adversary collects enough data. We find that users with high polarization and relevant interest are significantly more vulnerable, and we show that our attack is well-calibrated, allowing the adversary to target such vulnerable users. We finally validate our results for the emojis setting using user data from Twitter. Taken together, our results show that pool inference attacks are a concern for data protected by local differential privacy mechanisms with a large ε, emphasizing the need for additional technical safeguards and the need for more research on how to apply local differential privacy for multiple collections
Comparative Analysis of advanced Face Recognition Techniques
ABSTRACT: This project entitled "Comparative analysis of advanced Face Recognition Techniques", it is based on fuzzy c means clustering and associated sub neural network. It deals with the face is a complex multidimensional visual model and developing a computational model for face recognition is difficult. In this paper, it represents a method for face recognition base on similar neural networks. Neural networks (NNs) have been widely used in various fields. However, the computing effectiveness decreases rapidly if the scale of the NN increases. In this paper, a new method of face recognition based on fuzzy clustering and parallel NNs is proposed. The face patterns are divided into several small-scale neural networks based on fuzzy clustering and they are combine to obtain the recognition result. The facial feature vector was compared by PCA and LDA methods. In particular, the proposed method achieved 98.75% recognition accuracy for 240 patterns of 20 registrants and a 99.58% rejection rate for 240 patterns of 20 nonregistrants. Experimental results show that the performance of our new face-recognition method is better than those of the LDA based face recognition system
Interventions with pregnant women, new mothers and other primary caregivers for preventing early childhood caries (Review)
Evaluation of fractions and 5,7-dihydroxy-4',6-dimethoxy-flavone fromClerodendrum phlomidis Linn. F. against Helicoverpa armigera Hub.
CD14 Deficiency Impacts Glucose Homeostasis in Mice through Altered Adrenal Tone
The toll-like receptors comprise one of the most conserved components of the innate immune system, signaling the presence of molecules of microbial origin. It has been proposed that signaling through TLR4, which requires CD14 to recognize bacterial lipopolysaccharide (LPS), may generate low-grade inflammation and thereby affect insulin sensitivity and glucose metabolism. To examine the long-term influence of partial innate immune signaling disruption on glucose homeostasis, we analyzed knockout mice deficient in CD14 backcrossed into the diabetes-prone C57BL6 background at 6 or 12 months of age. CD14-ko mice, fed either normal or high-fat diets, displayed significant glucose intolerance compared to wild type controls. They also displayed elevated norepinephrine urinary excretion and increased adrenal medullary volume, as well as an enhanced norepinephrine secretory response to insulin-induced hypoglycemia. These results point out a previously unappreciated crosstalk between innate immune- and sympathoadrenal- systems, which exerts a major long-term effect on glucose homeostasis
Higher dietary salt intake is associated with microalbuminuria, but not with retinopathy in individuals with type 1 diabetes: the EURODIAB Prospective Complications Study
Lactosaminated mesoporous silica nanoparticles for asialoglycoprotein receptor targeted anticancer drug delivery
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Global, regional, and national burden of other musculoskeletal disorders, 1990-2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021
Background
Musculoskeletal disorders include more than 150 different conditions affecting joints, muscles, bones, ligaments, tendons, and the spine. To capture all health loss from death and disability due to musculoskeletal disorders, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) includes a residual musculoskeletal category for conditions other than osteoarthritis, rheumatoid arthritis, gout, low back pain, and neck pain. This category is called other musculoskeletal disorders and includes, for example, systemic lupus erythematosus and spondylopathies. We provide updated estimates of the prevalence, mortality, and disability attributable to other musculoskeletal disorders and forecasted prevalence to 2050.
Methods
Prevalence of other musculoskeletal disorders was estimated in 204 countries and territories from 1990 to 2020 using data from 68 sources across 23 countries from which subtraction of cases of rheumatoid arthritis, osteoarthritis, low back pain, neck pain, and gout from the total number of cases of musculoskeletal disorders was possible. Data were analysed with Bayesian meta-regression models to estimate prevalence by year, age, sex, and location. Years lived with disability (YLDs) were estimated from prevalence and disability weights. Mortality attributed to other musculoskeletal disorders was estimated using vital registration data. Prevalence was forecast to 2050 by regressing prevalence estimates from 1990 to 2020 with Socio-demographic Index as a predictor, then multiplying by population forecasts.
Findings
Globally, 494 million (95% uncertainty interval 431–564) people had other musculoskeletal disorders in 2020, an increase of 123·4% (116·9–129·3) in total cases from 221 million (192–253) in 1990. Cases of other musculoskeletal disorders are projected to increase by 115% (107–124) from 2020 to 2050, to an estimated 1060 million (95% UI 964–1170) prevalent cases in 2050; most regions were projected to have at least a 50% increase in cases between 2020 and 2050. The global age-standardised prevalence of other musculoskeletal disorders was 47·4% (44·9–49·4) higher in females than in males and increased with age to a peak at 65–69 years in male and female sexes. In 2020, other musculoskeletal disorders was the sixth ranked cause of YLDs globally (42·7 million [29·4–60·0]) and was associated with 83 100 deaths (73 600–91 600).
Interpretation
Other musculoskeletal disorders were responsible for a large number of global YLDs in 2020. Until individual conditions and risk factors are more explicitly quantified, policy responses to this burden remain a challenge. Temporal trends and geographical differences in estimates of non-fatal disease burden should not be overinterpreted as they are based on sparse, low-quality data.
Funding
Bill & Melinda Gates Foundation
Global, regional, and national burden of suicide, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
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