53 research outputs found
Insulin resistance, centripetal adipose tissue distribution and dietary intake in obese subjects
Total parenteral nutrition enriched with glutamine and ω-3 fatty acid in adult patients undergoing autologous stem cell transplantation.
Growth pattern and tectonic evolution of a regional low angle normal fault from sequential restoration techniques.
Sex-Differences in the Pattern of Comorbidities, Functional Independence, and Mortality in Elderly Inpatients: Evidence from the RePoSI Register.
BACKGROUND:
The RePoSi study has provided data on comorbidities, polypharmacy, and sex dimorphism in hospitalised elderly patients.
METHODS:
We retrospectively analysed data collected from the 2010, 2012, 2014, and 2016 data sets of the RePoSi register. The aim of this study was to explore the sex-differences and to validate the multivariate model in the entire dataset with an expanded follow-up at 1 year.
RESULTS:
Among 4714 patients, 51% were women and 49% were men. The disease distribution showed that diabetes, coronary artery disease, chronic obstructive pulmonary disease, chronic kidney disease, and malignancy were more frequent in men but that hypertension, anaemia, osteoarthritis, depression, and diverticulitis disease were more common in women. Severity and comorbidity indexes according to the Cumulative Illness Rating Scale (CIRS-s and CIRS-c) were higher in men, while cognitive impairment, mood disorders, and disability in daily life measured by the Barthel Index (BI) were worse in women. In the multivariate analysis, BI, CIRS, and malignancy significantly increased the risk of death in men at the 1-year follow-up, while age was independently associated with mortality in women.
CONCLUSIONS:
Our study highlighted the relevance and the validity of our previous predictive model in the identification of sex dimorphism in hospitalised elderly patients underscoring the need of sex-personalised health-care
Effects of a Combined Nutraceutical on Lipid Pattern, Glucose Metabolism and Inflammatory Parameters in Moderately Hypercholesterolemic Subjects: A Double-blind, Cross-over, Randomized Clinical Trial
Incidence, predictors, and treatment options of critical limb ischaemia after use of collagen plug-based vascular closure devices
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