20 research outputs found
Genetic Causes of Clopidogrel Nonresponsiveness: Which Ones Really Count?
Full text linkPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91111/1/phco.30.3.265.pd
ASYMPTOMATIC FIREFIGHTERS WITH METABOLIC SYNDROME HAVE A HIGH INCIDENCE OF BOTH CORONARY AND CAROTID PREMATURE ATHEROSCLEROSIS-ASSOCIATED WITH INCREASED THROMBOTIC AND INFLAMMATORY MARKERS
Get PDFIN ASYMPTOMATIC FIREFIGHTERS THE BURDEN OF SUBCLINICAL ATHEROSCLEROSIS AS MEASURED BY BOTH CORONARY ARTERY CALCIFICATION AND CAROTID INTIMAL MEDIAL THICKENING IS ASSOCIATED WITH METABOLIC ABNORMALITIES AND BUT NOT WITH STANDARD TRADITIONAL SEROLOGICAL RISK FACTORS
Get PDFGenetic Testing for Early Detection of Individuals at Risk of Coronary Heart Disease and Monitoring Response to Therapy: Challenges and Promises
Get PDFCoronary heart disease (CHD) often presents suddenly with little warning. Traditional risk factors are inadequate to identify the asymptomatic high-risk individuals. Early identification of patients with subclinical coronary artery disease using noninvasive imaging modalities would allow the early adoption of aggressive preventative interventions. Currently, it is impractical to screen the entire population with noninvasive coronary imaging tools. The use of relatively simple and inexpensive genetic markers of increased CHD risk can identify a population subgroup in which benefit of atherosclerotic imaging modalities would be increased despite nominal cost and radiation exposure. Additionally, genetic markers are fixed and need only be measured once in a patient’s lifetime, can help guide therapy selection, and may be of utility in family counseling
ASYMPTOMATIC FIREFIGHTERS WITH METABOLIC SYNDROME HAVE A HIGH INCIDENCE OF BOTH CORONARY AND CAROTID PREMATURE ATHEROSCLEROSIS-ASSOCIATED WITH INCREASED THROMBOTIC AND INFLAMMATORY MARKERS
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