10 research outputs found
Central nervous system virion detection in acute measles: histopathological, ultrastructural and pathogenetic aspects
Full text linkOrigins of vaginal acidity: high d/l lactate ratio is consistent with bacteria being the primary source
No full textComparison of an anti-HSV-2 monoclonal IgG and its IgA switch variant for topical immunoprotection of the mouse vagina
No full textTopically Applied Human Recombinant Monoclonal IgG1Antibody and Its Fab and F(ab′)2Fragments Protect Mice from Vaginal Transmission of HSV-2
Get PDFAbstractA recombinant human anti-herpes simplex virus monoclonal IgG1antibody and the corresponding Fab and F(ab′)2fragments were tested for efficacy in preventing vaginal transmission of HSV-2 infection in a well-established mouse model for genital herpes. IgG1, Fab, and F(ab′)2were approximately equally protective; vaginal delivery of 1–5 ng provided approximately 50% protection, and vaginal delivery of 400 ng completely protected mice from genital herpes infection (P< 0.001). These results suggest that topical applications of human monoclonal antibodies may be useful in developing new methods for preventing sexually transmitted disease
Cerebral endothelial cell infection by measles virus in subacute sclerosing panencephalitis: ultrastructural and in situ hybridization evidence
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Detection of human papillomavirus DNA sequences by in situ DNA-DNA hybridisation in cervical intraepithelial neoplasia and invasive carcinoma: a retrospective study.
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