Applying Web 2.0 in medical-related organizations

This study investigated the application of Web 2.0 to medical-related organizations. Thirty organizations participated in an online survey asking their perceived purposes, benefits and difficulties in using Web 2.0. The selected organizations fell into three categories: university medical libraries, hospitals, and non-profit organizations. Fourteen (46.7%) organizations were currently using Web 2.0, ten (33.3%) planned to use it in the future and six (20%) would not consider using it. A phone interview was further conducted with eight organizations (26.7%) about their opinion on Web 2.0. Results showed that most participants found the application of Web 2.0 beneficial to their organizations. Implications of this study for helping medical-related organizations make decisions regarding the use of Web 2.0 technologies in their organizations are discussed.postprintThe 6th International Conference on Knowledge Management (ICKM 2009), Hong Kong, 3-4 December 2009. In Proceedings of ICKM, 2009, p. 1-1

Severe liver failure due to influenza A infection in a hemodialysis patient

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Germline selection shapes human mitochondrial DNA diversity.

Approximately 2.4% of the human mitochondrial DNA (mtDNA) genome exhibits common homoplasmic genetic variation. We analyzed 12,975 whole-genome sequences to show that 45.1% of individuals from 1526 mother-offspring pairs harbor a mixed population of mtDNA (heteroplasmy), but the propensity for maternal transmission differs across the mitochondrial genome. Over one generation, we observed selection both for and against variants in specific genomic regions; known variants were more likely to be transmitted than previously unknown variants. However, new heteroplasmies were more likely to match the nuclear genetic ancestry as opposed to the ancestry of the mitochondrial genome on which the mutations occurred, validating our findings in 40,325 individuals. Thus, human mtDNA at the population level is shaped by selective forces within the female germ line under nuclear genetic control, which ensures consistency between the two independent genetic lineages.NIHR, Wellcome Trust, MRC, Genomics Englan

Magnitude, temporal trends, and inequalities in the DALYs and YLDs of nutritional deficiency among older adults in the Western Pacific region : findings from the Global Burden of Disease Study 1990–2019

202208 bckwVersion of RecordSelf-fundedPublishe

Psychometric properties of the trail walking test for people with stroke

202307 bcchVersion of RecordRGCPublishe